Results 41 to 50 of about 22,323 (211)

Skin tissue expression and serum level of thymic stromal lymphopoietin in patients with psoriasis vulgaris

Dermatology Reports, 2019
Thymic stromal lymphopoietin (TSLP) is known to be associated with allergic diseases. It is also suggested that TSLP has a role in autoimmune diseases such as psoriasis; however, the associated pathways remain unknown.
Oki Suwarsa, Hartati Purbo Dharmadji, Endang Sutedja, Lengga Herlina, Putri Reno Sori, Reti Hindritiani, Reiva Farah Dwiyana, Hendra Gunawan   +7 more
doaj   +1 more source

Expression of Thymic Stromal Lymphopoietin in Immune-Related Dermatoses

Mediators of Inflammation, 2022
Thymic stromal lymphopoietin (TSLP), long known to be involved in Th2 response, is also implicated in multiple inflammatory dermatoses and cancers. The purpose of this study was to improve our understanding of the expression of TSLP in the skin of those ...
Si-Zhe Li, Xin-Xing Jin, Yin Shan, Hong-Zhong Jin, Ya-Gang Zuo   +4 more
doaj   +1 more source

Type 2 Innate Lymphoid Cells in Allergic Disease. [PDF]

, 2013
Type II innate lymphoid cells (ILC2) are a novel population of lineage-negative cells that produce high levels of Th2 cytokines IL-5 and IL-13. ILC2 are found in human respiratory and gastrointestinal tissue as well as in skin.
Doherty, Taylor A, Lund, Sean, Walford, Hannah H   +2 more
core   +2 more sources

A Comparative Study on Serum Levels of “Thymic Stromal Lymphopoietin” Between Patients with Psoriasis Vulgaris and Healthy Individuals: A Case-Control Study

Indian Dermatology Online Journal
Background: Thymic stromal lymphopoietin (TSLP) is a cytokine initially implicated to be associated with allergic disorders inducing Th2 response. Emerging studies have shown that TSLP is also involved in autoimmune diseases.
Siri Sri Kollabathula, Konakanchi Venkatachalam, Kethireddi Susmitha Divya, Patnala Guruprasad, Pallapati Anila Sunandini Nayar   +4 more
doaj   +1 more source

Anti-TSLP antibodies: Targeting a master regulator of type 2 immune responses

Allergology International, 2020
TSLP is an epithelial cell-derived cytokine synthesized in response to various stimuli, including protease allergens and microorganisms like viruses and bacteria. Biological functions of TSLP require heterodimer formation between the TSLP receptor (TSLPR)
Saeko Nakajima, Hiroki Kabata, Kenji Kabashima, Koichiro Asano   +3 more
doaj   +1 more source

TSLP regulates mitochondrial ROS-induced mitophagy via histone modification in human monocytes

Cell & Bioscience, 2022
Background Thymic stromal lymphopoietin (TSLP) is a Th2-like cytokine involved in asthma pathogenesis. Excessive reactive oxygen species (ROS) production can lead to airway inflammation, hyperresponsiveness and remodeling.
Yi-Ching Lin, Yu-Chih Lin, Mei-Lan Tsai, Wei-Ting Liao, Chih-Hsing Hung   +4 more
doaj   +1 more source

Abnormal thymic stromal lymphopoietin expression in the duodenal mucosa of patients with coeliac disease [PDF]

, 2015
OBJECTIVE: The short isoform of thymic stromal lymphopoietin (TSLP), a cytokine constitutively expressed by epithelial cells, is crucial in preserving immune tolerance in the gut.
Alastair Forbes, Alessandra Pasini, Alessandro Vanoli, Andoh, Antonio Di Sabatino, Biancheri, Bjerkan, Caruso, Christmann, Ciccocioppo, Ciccocioppo, Cinzia Papadia, Comeau, Corazza, Cristina Ubezio, Datta, Daum, Di Sabatino, Di Sabatino, Di Sabatino, Di Sabatino, Eleanor Wood, Fornasa, Gino R Corazza, Giulia Fornasa, He, Iliev, Iliev, Iliev, Kashyap, Katerina Tsilingiri, Liu, Maria Rescigno, Monteleone, Monteleone, Nagarkar, Otte, Paolo Biancheri, Paolo Giuffrida, Pender, Pender, Rescigno, Rimoldi, Roan, Rubio-Tapia, Spadoni, Sylvia L F Pender, Takai, Thomas, Thomas T MacDonald, Usategui, Vaira, Zhou, Ziegler   +53 more
core   +1 more source

Mucosal immune responses following intestinal nematode infection. [PDF]

, 2014
In most natural environments, the large majority of mammals harbour parasitic helminths that often live as adults within the intestine for prolonged periods (1-2 years).
Else KJ, Garcia FT, McSharry C, Nakajima H, Oku Y, Pawlowski Z, Petit‐Frere C, Robinson K, Tilney LG, Urban JF, WHO, WHO   +11 more
core   +4 more sources

Chitin-Induced Airway Epithelial Cell Innate Immune Responses Are Inhibited by Carvacrol/Thymol. [PDF]

, 2016
Chitin is produced in large amounts by fungi, insects, and other organisms and has been implicated in the pathogenesis of asthma. Airway epithelial cells are in direct contact with environmental particles and serve as the first line of defense against ...
Erle, David J, Khosravi, Ali Reza
core   +3 more sources

Cellular and Molecular Mechanisms of TSLP Function in Human Allergic Disorders - TSLP Programs the “Th2 code” in Dendritic Cells

Allergology International, 2012
Thymic stromal lymphopoietin (TSLP) has been recently implicated as a key molecule for initiating allergic inflammation at the epithelial cell-dendritic cell (DC) interface.
Tomoki Ito, Yong-Jun Liu, Kazuhiko Arima
doaj   +1 more source