Results 31 to 40 of about 441 (127)
The Role of Viruses in Cellular Transformation and Cancer. [PDF]
Cancer Rep (Hoboken)ABSTRACT Background Viral infections are established contributors to oncogenesis, leading to significant public health challenges. This systematic review aims to synthesize current knowledge on the mechanisms of viral cellular transformation and their association with various cancers.
Damian D.
europepmc +2 more sources
JC and Human polyomavirus 9 after kidney transplantation: an exploratory serological cohort study [PDF]
, 2021 Introduction: Human polyomaviruses (HPyVs) cause disease in immunocompromised patients. BK polyomavirus (BKPyV) for instance persistently infects the kidneys. In kidney transplant recipients, (KTRs) BKPyV can cause allograft nephropathy.
Kamminga, Sergio +11 more
core +1 more source
Intercellular Transmission of Naked Viruses through Extracellular Vesicles: Focus on Polyomaviruses
Viruses, 2020 Extracellular vesicles have recently emerged as a novel mode of viral transmission exploited by naked viruses to exit host cells through a nonlytic pathway.
Francois Helle +4 more
doaj +1 more source
Genetic Diversity of the Noncoding Control Region of the Novel Human Polyomaviruses
Viruses, 2020 The genomes of polyomaviruses are characterized by their tripartite organization with an early region, a late region and a noncoding control region (NCCR).
Ugo Moens +2 more
doaj +1 more source
Human polyomaviruses and cancer: an overview
Clinics, 2018 The name of the family Polyomaviridae, derives from the early observation that cells infected with murine polyomavirus induced multiple (poly) tumors (omas) in immunocompromised mice. Subsequent studies showed that many members of this family exhibit the
José Carlos Mann Prado +5 more
doaj +1 more source
Prevalence of DNA of fourteen human polyomaviruses determined in blood donors
Transfusion, Volume 59, Issue 12, Page 3689-3697, December 2019., 2019 Abstract BACKGROUND Human polyomaviruses (HPyVs), like herpesviruses, cause persistent infection in a large part of the population. In immunocompromised and elderly patients, PyVs cause severe diseases such as nephropathy (BK polyomavirus [BKPyV]), progressive multifocal leukoencephalopathy (JC polyomavirus [JCPyV]), and skin cancer (Merkel cell ...
Sergio Kamminga +4 more
wiley +1 more source
TSPyV binds to sialic acid containing glycolipids.
, 2015 Cell binding analysis of thio-labelled Alexa Fluor 488 TSPyV VP1 pentamers to HEK293 cells treated with inhibitors interfering with the synthesis of glycosphingolipids, N. and O-linked glycoproteins.
Bärbel S. Blaum (114952) +6 more
core +1 more source
Multiplex detection in tonsillar tissue of all known human polyomaviruses
BMC Infectious Diseases, 2017 Background In the past few years, eleven new human viruses have joined the two previously known members JCPyV and BKPyV of the Polyomaviridae family, by virtue of molecular methods.
Mohammadreza Sadeghi +7 more
doaj +1 more source
Journal of the European Academy of Dermatology and Venereology, 2015 AbstractBackgroundThe discovery, from 2007, of eight new human polyomaviruses (HPyVs) has revived interest in the Polyomaviridae family and their association with human diseases and cancer. In particular, HPyV6 and HPyV7 were discovered in skin swabs of healthy donors and TSPyV was discovered in a heart transplant recipient affected by virus‐associated
FAVA, PAOLO +8 more
openaire +3 more sources
Comparing Effects of BK Virus Agnoprotein and Herpes Simplex‐1 ICP47 on MHC‐I and MHC‐II Expression
Journal of Immunology Research, Volume 2013, Issue 1, 2013., 2013 Background. Among human polyomaviruses, only BK virus (BKV) and JC virus (JCV) encode an agnoprotein upstream of VP1 on the viral late transcript. BKV agnoprotein is abundantly expressed late in the viral life cycle, but specific cellular and humoral immune responses are low or absent.
Michela Cioni +4 more
wiley +1 more source