Results 41 to 50 of about 441 (127)

TSPyV VP1 specifically binds to terminal Neu5Ac.

, 2015
(A) Crystal structure of the unassembled TSPyV VP1 pentamer in complex with the GM1 glycan. The TSPyV VP1 pentamer is shown in cartoon representation with one monomer depicted in purple. Glycan residues are shown in stick representations and glycan atoms
Bärbel S. Blaum (114952), Mariet C. W. Feltkamp (244842), Luisa J. Ströh (469044), Walter J. Atwood (469045), Aisling S. Dugan (603948), Gretchen V. Gee (786526), Thilo Stehle (114963)   +6 more
core   +1 more source

Structural Basis and Evolution of Glycan Receptor Specificities within the Polyomavirus Family

mBio, 2020
Asymptomatic infections with polyomaviruses in humans are common, but these small viruses can cause severe diseases in immunocompromised hosts. New Jersey polyomavirus (NJPyV) was identified via a muscle biopsy in an organ transplant recipient with ...
Luisa J. Ströh, Nils H. Rustmeier, Bärbel S. Blaum, Josephine Botsch, Philip Rößler, Florian Wedekink, W. Ian Lipkin, Nischay Mishra, Thilo Stehle   +8 more
doaj   +1 more source

Review on the Relationship between Human Polyomaviruses‐Associated Tumors and Host Immune System

Journal of Immunology Research, Volume 2012, Issue 1, 2012., 2012
The polyomaviruses are small DNA viruses that can establish latency in the human host. The name polyomavirus is derived from the Greek roots poly‐, which means “many,” and ‐oma, which means “tumours.” These viruses were originally isolated in mouse (mPyV) and in monkey (SV40).
Serena Delbue, Manola Comar, Pasquale Ferrante, Ludovica Segat   +3 more
wiley   +1 more source

Human Polyomaviruses in Skin Diseases

Pathology Research International, Volume 2011, Issue 1, 2011., 2011
Polyomaviruses are a family of small, nonenveloped viruses with a circular double‐stranded DNA genome of ~5,000 base pairs protected by an icosahedral protein structure. So far, members of this family have been identified in birds and mammals. Until 2006, BK virus (BKV), JC virus (JCV), and simian virus 40 (SV40) were the only polyomaviruses known to ...
Ugo Moens, Maria Ludvigsen, Marijke Van Ghelue, Gerardo Ferrara   +3 more
wiley   +1 more source

Detection of antibodies to MCPyV, PtvPyV1, PtvPyV2, TSPyV and OraPyV1 polyomaviruses in 16 great apes.

, 2014
Detection of antibodies to MCPyV, PtvPyV1, PtvPyV2, TSPyV and OraPyV1 polyomaviruses in 16 great apes.
Jérôme T. J. Nicol (561901), Pierre Coursaget (561903), Mauro Tognon (311647), Etienne Liais (561902), Antoine Touzé (323722), Romain Potier (385822), Elisa Mazzoni (407132)   +6 more
core   +1 more source

Trichodysplasia Spinulosa Polyomavirus in Respiratory Tract of Immunocompromised Child

Emerging Infectious Diseases, 2018
Trichodysplasia spinulosa polyomavirus causes trichodysplasia spinulosa, a skin infection, in immunocompromised persons, but the virus is rarely detected in respiratory samples. Using PCR, we detected persistent virus in respiratory and skin samples from
Arwa A. Bagasi, Tasneem Khandaker, Gemma Clark, Terry Akagha, Jonathan K. Ball, William L. Irving, C. Patrick McClure   +6 more
doaj   +1 more source

Unique location of the TSPyV Neu5Ac binding site.

, 2015
The location of the Neu5Ac binding site on TSPyV VP1 is shifted compared to binding sites of polyomaviruses SV40, BKPyV, JCPyV, MCPy, LPyV, HPyV9 and MPyV, which all engage sialylated glycans by employing a Neu5Ac binding site in a conserved location on ...
Bärbel S. Blaum (114952), Mariet C. W. Feltkamp (244842), Luisa J. Ströh (469044), Walter J. Atwood (469045), Aisling S. Dugan (603948), Gretchen V. Gee (786526), Thilo Stehle (114963)   +6 more
core   +1 more source

Primary Polyomavirus Infection, Not Reactivation, as the Cause of Trichodysplasia Spinulosa in Immunocompromised Patients [PDF]

, 2017
Classic human polyomaviruses (JC and BK viruses) become pathogenic when reactivating from latency. For the rare skin disease trichodysplasia spinulosa, we show that manifestations of the causative polyomavirus (TSPyV) occur during primary infection of ...
van der Zon, Arnulfo J., Vries, K. de, van Kampen, Jeroen J A, Meijden, E. van der, Hedman, K., Rácz, Emöke, Hedman, Klaus, de Vries, Karin, Diercks, G.F., de Weerd, Annelies E., van der Blij-Brouwer, Caroline S, Raez, Emoke, van der Meijden, E, Diercks, GF, Diercks, Gilles F, Kroes, Aloys C M, de Weerd, Annelies E, Nijland, M, van der Blij-de Brouwer, Caroline S., van Kampen, Jeroen J. A., Zon, A.J. van der, Horváth, Barbara; id_orcid, Raez, E., Feltkamp, Mariet C. W., Horvath, B., de Weerd, Annelies, Diercks, Gilles F; id_orcid, Kroes, Aloys C. M., Horváth, Barbara, Riezebos-Brilman, Annelies, van der Blij-de Brouwer, CS, Clahsen - van Groningen, Marian; id_orcid, Diercks, Gilles F., van der Meijden, Els, van der Zon, Arnulfo J, van der Zon, AJ, Nijland, Marcel; id_orcid, Horvath, B, Rácz, Emöke; id_orcid, Feltkamp, MCW, Blij-de Brouwer, C.S. van der, Riezebos-Brilman, A., Clahsen-van Groningen, Marian C, Feltkamp, M.C.W., Vries, K, Clahsen - van Groningen, Marian, Weerd, A.E. de, Nijland, M., Hedman, K, Kroes, A.C.M., Kampen, J.J.A. van, Riezebos-Brilman, A, Kroes, ACM, Clahsen-van Groningen, Marian C., Feltkamp, Mariet C W, Nijland, Marcel, van Kampen, Jeroen, Clahsen-van Groningen, M.C.   +57 more
core   +1 more source

Colocalization of TSPyV LT-antigen, Ki-67 and phosphorylated pRB.

, 2014
TSPyV LT-antigen (red) (A1) with Ki-67 (green) (A2) and merge (yellow) (A3) in a vertical section of hair follicle of TS10 is shown in the upper row. A higher magnification of TSPyV LT-antigen (B1) with Ki-67 (green) (B2) and merge (yellow) (B3) in a ...
Mariet C. W. Feltkamp (244842), Elena Pope (640809), Arlene S. Rosenberg (640808), Philip Fleckman (152280), Taylor Benoit (640810), Siamaque Kazem (640807), Richard C. Wang (252512), Els van der Meijden (244837)   +7 more
core   +1 more source

Cell cycle regulation markers and TSPyV LT-antigen expression.

, 2014
Sections of healthy epidermis (A1–A4), healthy hair follicle (B1–B4), TS epidermis (C1–C4) and TS follicle (D1–D4) are stained for p16ink4a (first panel), p21waf (second panel), pRB (third panel) and TSPyV (fourth panel).
Mariet C. W. Feltkamp (244842), Elena Pope (640809), Arlene S. Rosenberg (640808), Philip Fleckman (152280), Taylor Benoit (640810), Siamaque Kazem (640807), Richard C. Wang (252512), Els van der Meijden (244837)   +7 more
core   +1 more source