Results 101 to 110 of about 59,427 (290)

Estimating the Factor VIII‐Equivalent Activity of Emicizumab Using Global Assays of Haemostasis

Haemophilia, EarlyView.
ABSTRACT Background Emicizumab is a bispecific monoclonal antibody mimicking factor (F) VIII activity and an effective therapy for prophylaxis in people with haemophilia A (PWHA). The FVIII‐equivalent activity (FVIIIeq) of emicizumab remains unknown. Objectives To estimate FVIIIeq of emicizumab using global assays of haemostasis.
Daniel Kraemmer, Cihan Ay, Judit Rejtő, Georg Heinze, Peter Quehenberger, Ingrid Pabinger, Oliver Königsbrügge   +6 more
wiley   +1 more source

Co‐Occurrence of HIV‐Susceptibility and ‐Protective HLA Alleles Is a Possible Contributor to the Development of Primary HIV‐Associated Thrombocytopenia (PHAT): A Cross‐Sectional Study

International Journal of Immunogenetics, EarlyView.
ABSTRACT Primary HIV‐associated thrombocytopenia (PHAT) is an isolated thrombocytopenia in HIV‐positive individuals in the absence of secondary causes. The presence of certain Human Leukocyte Antigens (HLA) has been linked to individuals’ immune response to HIV and the development of immune‐mediated thrombocytopenic disorders.
Walter J Janse van Rensburg, Anne‐Cecilia van Marle, Lomari Geertsema   +2 more
wiley   +1 more source

Circulating immune complexes in thrombotic thrombocytopenic purpura (TTP) [letter] [PDF]

, 1978
Antonio Celada, LH Perrin
openalex   +1 more source

ADAMTS13 in the New Era of TTP

International Journal of Molecular Sciences
Thrombotic thrombocytopenic purpura (TTP) is a life-threatening, often immune-mediated disease that affects 2–13 persons per million per year. Hemolytic anemia, thrombocytopenia, and end-organ damage due to the formation of microthrombi are characteristic of TTP.
Anna Papakonstantinou, Panagiotis Kalmoukos, Aikaterini Mpalaska, Evaggelia-Evdoxia Koravou, Eleni Gavriilaki   +4 more
openaire   +2 more sources

Common Hematologic Emergencies—Acute Promyelocytic Leukemia and Microangiopathic Hemolytic Anemias—A Pivotal Role of Clinical Laboratory

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Hematologic emergencies are urgent health conditions which result in significant mortality and morbidity unless timely therapeutic measures are taken. Therapeutic success depends on their timely and accurate recognition by hematology laboratory services.
Ganna Shestakova, Nicolas Ulrich Edgar, Anton V. Rets   +2 more
wiley   +1 more source

Vitamin B12 deficiency in thrombotic thrombocytopenic purpura-like cases

European Journal of Case Reports in Internal Medicine
Background: Thrombotic microangiopathies (TMA) are characterized by a triad of microangiopathic hemolytic anemia, thrombocytopenia, and organ damage which occur in the setting of endothelial damage and platelet activation.
Inemesit Akpan, Ghida Akhdar, Kaelan Dawson, Amanda Hathaway   +3 more
doaj   +1 more source

Comparison of 10 TTP and Tmax Estimation Techniques for MR Perfusion-Diffusion Mismatch Quantification in Acute Stroke

American Journal of Neuroradiology, 2013
BACKGROUND AND PURPOSE: The mismatch between lesions identified in perfusion- and diffusion-weighted MR imaging is typically used to identify tissue at risk of infarction in acute stroke.
N. D. Forkert, P. Kaesemann, A. Treszl, S. Siemonsen, B. Cheng, H. Handels, J. Fiehler, G. Thomalla   +7 more
semanticscholar   +1 more source

Acute Plasmodium yoelii 17XNL Infection During BCG Vaccination Limits T Cell Responses and Mycobacterial Growth Inhibition

Immunology, EarlyView.
Tuberculosis and malaria overlap in many sub‐Saharan African countries where BCG vaccination is routinely administered. The aim of this study was to determine whether the timing of BCG vaccination in relation to a malaria infection has implications for BCG vaccine efficacy.
Emily Tangie, Nawamin Pinpathomrat, Rachel Tanner, Nai‐Jen Hsu, Alexandra J. Spencer, Muazzam Jacobs, Helen Mcshane, Roanne Keeton   +7 more
wiley   +1 more source

GOP or TTP?

, 2023
The Texas ...
openaire   +2 more sources

Approximation algorithms for TTP(2)

Mathematical Methods of Operations Research, 2012
We consider the traveling tournament problem, which is a well-known benchmark problem in tournament timetabling. It consists of designing a schedule for a sports league of n teams such that the total traveling costs of the teams are minimized. The most important variant of the traveling tournament problem imposes restrictions on the number of ...
Thielen, Clemens, Westphal, Stephan
openaire   +3 more sources