Results 21 to 30 of about 245,422 (162)

Gut Epithelium of the Highly Toxic Ribbon Worm Cephalothrix cf. simula (Palaeonemertea, Nemertea) Contains Tetrodotoxin-Positive Bacterial Endosymbionts [PDF]

Toxins
Tetrodotoxin (TTX), widely known as pufferfish venom, is a low-molecular-weight guanidinium neurotoxin. It can accumulate to extremely high concentrations in certain animals, including pufferfish, blue-ringed octopuses, flatworms, and nemerteans. However,
Timur Yu. Magarlamov, Grigorii V. Malykin   +1 more
doaj   +2 more sources

Tetrodotoxin, an Extremely Potent Marine Neurotoxin: Distribution, Toxicity, Origin and Therapeutical Uses

Marine Drugs, 2015
Tetrodotoxin (TTX) is a potent neurotoxin responsible for many human intoxications and fatalities each year. The origin of TTX is unknown, but in the pufferfish, it seems to be produced by endosymbiotic bacteria that often seem to be passed down the ...
Jorge Lago, Laura P. Rodríguez, Lucía Blanco, Juan Manuel Vieites, Ana G. Cabado   +4 more
doaj   +2 more sources

The Chemistry and Biology of the Tetrodotoxin Natural Product Family. [PDF]

Angew Chem Int Ed Engl
Tetrodotoxin is best known as the poison of the pufferfish, which is a delicacy in Japanese cuisine. Its toxicity arises from the selective blockage of NaV channels, which is depicted for the NaV1.7 pore, highlighting the DEKA motif, which permeates sodium ions.
Nißl B, Mülbaier M, Grisoni F, Trauner D, Bermúdez M, Dialer C, Konrad DB.   +6 more
europepmc   +2 more sources

Short-Chain Fatty-Acid-Producing Bacteria: Key Components of the Human Gut Microbiota

Nutrients, 2023
Short-chain fatty acids (SCFAs) play a key role in health and disease, as they regulate gut homeostasis and their deficiency is involved in the pathogenesis of several disorders, including inflammatory bowel diseases, colorectal cancer, and ...
Manuel Bernabeu, Marco Cintoni, Serena Porcari   +2 more
exaly   +2 more sources

Hungry for Knowledge: Octopamine Signaling Regulates Hunger-Enhanced Olfactory Learning. [PDF]

Adv Sci (Weinh)
Researchers demonstrate that hunger state facilitates both aversive and appetitive olfactory learning. Two distinct octopamine signaling pathways are involved in aversive or appetitive memory formation in the hunger state. And, hunger state also facilitates the formation of both types of memories via an evolutionarily conserved norepinephrine (the ...
Zhao H, Shi G, Qin R, Sun Y, Guo W, Shi R, Peng M, Yang J, Zhao J, Liu Q, Xiao J, Zhang K, Liu Q, Yang W, Liu H.   +14 more
europepmc   +2 more sources

Isolation and Toxigenic Characteristics of a Tetrodotoxin Producing Bacteria

Turkish Journal of Fisheries and Aquatic Sciences, 2021
Tetrodotoxin (TTX) is a kind of neurotoxin with great scientific research and medicinal value. Studies have confirmed that microorganism is one of the important sources of TTX.
Yongjun Yuan, F. Guan, Chen Yu, Zhuo Chen, Jie Zhang   +4 more
semanticscholar   +1 more source

Intracellular immunohistochemical detection of tetrodotoxin in Pleurobranchaea maculata (Gastropoda) and Stylochoplana sp. (Turbellaria) [PDF]

, 2015
Tetrodotoxin (TTX), is a potent neurotoxin targeting sodium channels that has been identified in multiple marine and terrestrial organisms. It was recently detected in the Opisthobranch Pleurobranchaea maculata and a Platyhelminthes Stylochoplana sp ...
Cary, Stephen Craig, Salvitti, Lauren R., Susanna A. Wood, Lauren Salvitti, Winsor, Leigh, Cary, S. Craig, Susanna Wood, Wood, Susanna A., Leigh Winsor, Stephen Cary, Lauren R. Salvitti, Stephen Craig Cary   +11 more
core   +1 more source

New Invasive Nemertean Species (Cephalothrix Simula) in England with High Levels of Tetrodotoxin and a Microbiome Linked to Toxin Metabolism

Marine Drugs, 2018
The marine nemertean Cephalothrix simula originates from the Pacific Ocean but in recent years has been discovered in northern Europe. The species has been associated with high levels of the marine neurotoxin Tetrodotoxin, traditionally associated with ...
Andrew D. Turner, David Fenwick, Andy Powell, Monika Dhanji-Rapkova, Charlotte Ford, Robert G. Hatfield, Andres Santos, Jaime Martinez-Urtaza, Tim P. Bean, Craig Baker-Austin, Paul Stebbing   +10 more
doaj   +1 more source

High colonization rates of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli [PDF]

, 2014
BACKGROUND International travel contributes to the worldwide spread of multidrug resistant Gram-negative bacteria. Rates of travel-related faecal colonization with extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae vary for different ...
Battegay, Manuel, Widmer, Andreas F., Andreas Neumayr, Frei, Reno, Neumayr, Andreas, Hatz, Christoph, Jaeger, Veronika K., Veronika K Jaeger, Johannes Blum, Sabine Haller, Andreas F Widmer, Susan DeCrom, Blum, Johannes, Reno Frei, Furrer, Hansjakob, Endimiani, Andrea, Hansjakob Furrer, DeCrom, Susan, Jaeger, Veronika K, Haller, Sabine, Manuel Battegay, Andrea Endimiani, Esther Kuenzli, Widmer, Andreas F, Christoph Hatz, Kuenzli, Esther   +25 more
core   +1 more source

No evidence for a culturable bacterial tetrodotoxin producer in Pleurobranchaea maculata (Gastropoda: Pleurobranchidae) and Stylochoplana sp. (Platyhelminthes: Polycladida)

, 2015
Tetrodotoxin (TTX) is a potent neurotoxin found in the tissues of many taxonomically diverse organisms. Its origin has been the topic of much debate, with suggestions including endogenous production, acquisition through diet, and symbiotic bacterial ...
Salvitti, Lauren R., Susanna A. Wood, Paul McNabb, Lauren Salvitti, McNabb, Paul, Cary, S. Craig, Susanna Wood, Wood, Susanna A., Stephen Cary, Lauren R. Salvitti, Stephen Craig Cary   +10 more
core   +1 more source