Results 41 to 50 of about 245,422 (162)

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

Advanced Science, Volume 13, Issue 36, 29 June 2026.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi, Pierre Parutto, Yuyi Zhang, Tasuku Konno, Cecile Crapart, Raquel Pereira, John P. Franklin, Mosab Ali Awadelkareem, Daniel C Maddison, Michael J. Devine, Edgar R. Gomes, Joseph Chambers, Elena Koslover, Edward Avezov   +13 more
wiley   +1 more source

Spontaneous Non‐Catalyzed Molecular Reactions and Interactions in the Human Body: Biomedical Implications

Advanced Science, Volume 13, Issue 36, 29 June 2026.
ABSTRACT The human body functions as a natural reactor for a vast network of chemical and biological reactions and physical interactions among small molecules, proteins, cells, and numerous other components. These reactions/interactions are essential for maintaining normal physiological functions.
Yuhao Cai, Chao Zhao
wiley   +1 more source

rRNA gene restriction patterns as a characterization tool for Lactobacillus sake strains producing ropy slime

, 1996
http://www.elsevier.nl/locate/01681605The rRNA gene restriction patterns (ribotypes) of 69 ropy slime producing Lactobacillus sake strains isolated mainly from vacuum-packaged meat products of ten meat plants were determined.
Björkroth, Johanna, Hannu Korkeala, Korkeala, Hannu, Johanna Björkroth   +3 more
core   +1 more source

Identification and Optimization Study of Lipase Producing Bacteria Isolated from Municipal Waste and Bio-deteriorated Waste

, 2022
Bio-deteriorated waste is the leftover organic matter of unwanted raw food which if not handled properly or left for natural degradation can cause health issues. Microorganisms have the ability to biodegrade waste by secreting enzymes.
Arvindkumar Dungrechiya, Harshitkumar J. Savalia   +1 more
core   +2 more sources

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, Volume 600, Issue 10, Page 1491-1518, May 2026.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

A mixed community of actinomycetes produce multiple antibiotics for the fungus farming ant Acromyrmex octospinosus [PDF]

, 2010
BACKGROUND: Attine ants live in an intensely studied tripartite mutualism with the fungus Leucoagaricus gongylophorus, which provides food to the ants, and with antibiotic-producing actinomycete bacteria.
Bibb, Mervyn J., Sabine Grüschow, Heavens, Darren, Goss, Rebecca J. M., Yu, Douglas W., Drou Nizar, Barke Jörg, Darren Heavens, Barke, Jörg, Grüschow, Sabine, Hutchings Matthew I, Mervyn J Bibb, Drou, Nizar, Hutchings, Matthew I., Jörg Barke, Matthew I Hutchings, Ryan F Seipke, Nizar Drou, Grüschow Sabine, Goss Rebecca JM, Douglas W Yu, Yu Douglas W, Seipke, Ryan F., Barke, Joerg, Rebecca JM Goss, Seipke Ryan F, Heavens Darren, Grueschow, Sabine, Yu, Douglas, Bibb Mervyn J   +29 more
core   +1 more source

SEMI‐1, A Novel Neuronal Selenium‐Binding Protein 1 Homolog Without Methanethiol Oxidase Activity, Modulates Stress Resistance, Lifespan, and Thermotaxis in C. elegans

BioFactors, Volume 52, Issue 3, May/June 2026.
SEMI‐1 is a selenium‐binding protein in C. elegans that, different from its paralog, SEMO‐1, and its human ortholog, SELENBP1, has no enzymatic activity as a methanethiol oxidase. It is expressed in AFD and BAG neurons only and affects nematode thermotaxis, stress resistance, and lifespan.
Weiye Gong, Karl Köhnlein, Josephine Priebs, Lara Biegel, Nadine Urban, Verena Alexia Ohse, David Guerrero‐Gómez, Priscila Yumi Tanaka Shibao, Janine Kirstein, Anna Patricia Kipp, Holger Steinbrenner, Antonio Miranda‐Vizuete, Martin Srayko, Lars‐Oliver Klotz   +13 more
wiley   +1 more source

Nonclassical MHC‐I Molecules: Emerging Therapeutic Targets in Next‐Generation Immunotherapy

MedComm, Volume 7, Issue 5, May 2026.
Immunotherapies dependent on classical MHC‐I molecules face significant challenges, including extreme polymorphism and frequent downregulation in pathological conditions. This review discusses how nonclassical MHC‐I molecules (HLA‐E, HLA‐F, HLA‐G, CD1, MR1) may potentially circumvent these limitations through restricted genetic diversity, stable ...
Wanlin He, Andrew J. McMichael
wiley   +1 more source

Isolation and Characterization of Antibiotic-producing Endophytic Bacteria from Citrus aurantifolia Swingle

, 2018
Research on the isolation and characterization of antibiotics-producing endophytic bacteria from Citrus aurantifolia leaves has been done. The isolation process was carried out by spreading spread plate isolation technique, screening of antibiotic ...
Mifthahul Jannah, Asiska Permata Dewi, Yufri Aldi, Syukria Ikhsan Zam, Anthoni Agustien, Akmal Djamaan, Rika Sari Lalfari   +6 more
core   +1 more source

Prevalence of multiresistant gram-negative organisms in a tertiary hospital in Mwanza, Tanzania. [PDF]

, 2009
\ud Antimicrobial resistance is fast becoming a global concern with rapid increases in multidrug-resistant Gram negative organisms. The prevalence of extended spectrum beta-lactamase (ESBL)-producing clinical isolates increases the burden on implementing
Kamugisha, Erasmus, Chakraborty Trinad, Mirambo Mariam, Mshana, S.E., Mirambo, M., Stephen E Mshana, Mariam Mirambo, Kamugisha Erasmus, Erasmus Kamugisha, Mshana Stephen E, Lyamuya Eligius F, Mirambo, Mariam, Lyamuya, Eligius F, Eligius F Lyamuya, Chakraborty, T., Chakraborty, Trinad, Lyamuya, E.F., Mshana, Stephen E, Kamugisha, E., Trinad Chakraborty   +19 more
core   +1 more source