Results 101 to 110 of about 29,634 (242)
Marine toxins - saxitoxin (STX) and tetrodotoxin (TTX)
, 2015 Saxitoxin (STX) and tetrodotoxin (TTX) are two of the most poisonous marine biotoxins known. They have a very interesting history, both used as a means for suicide and murder STX has been announced publicly by the world`s governments as a chemical weapon,
Georgieva, Marieta +1 more
core +1 more source
Trafficking and potentiation of Nav1.7 and Nav1.8 channels are mediated by IQGAP1
The Journal of Physiology, EarlyView.Abstract figure legend IQGAP1 binds to the voltage‐gated Nav1.7 and Nav1.8 channels and TRPA1 channels in sensory neurons. Inflammatory mediators (IM), including PGE2 and TNFα, released during nerve injury and inflammation activate intracellular signalling messengers such as PKA, p38 MAPK and Cdc42 through their respective receptors.
Xuming Zhang +2 more
wiley +1 more source
Automated Patch Clamp for the Detection of Tetrodotoxin in Pufferfish Samples
Marine DrugsTetrodotoxin (TTX) is a marine toxin responsible for many intoxications around the world. Its presence in some pufferfish species and, as recently reported, in shellfish, poses a serious health concern. Although TTX is not routinely monitored, there is a
Mònica Campàs +5 more
doaj +1 more source
Five Advances in the Last 50 Years That Have Impacted Endocrine Surgery
World Journal of Surgery, EarlyView.
Matilda Anneback +5 more
wiley +1 more source
Early Developmental Neuronal Activity Impacts Oligodendrocyte Differentiation Through AMPA Receptors
Glia, Volume 74, Issue 8, August 2026.In early brain development, neuronal activity reduces OPC differentiation. Decreased neuronal activity changes oligodendrocyte gene expression, including upregulating glutamate receptor genes. AMPA signaling regulates the final stages of OPC differentiation.
Tessa E. Allen +4 more
wiley +1 more source
Lack of multiplicative scaling after in vivo TTX-treatment.
, 2013 (A–C) Plots of miniature events, ranked by amplitude, from TTX-treated versus control cells are shown; inserts: cumulative distribution plots of control amplitudes and scaled TTX events (for scaling details see text; scaling factors: juvenile mEPSCs = 1 ...
Kevin D. Graber (77509) +3 more
core +1 more source
Synthesis of ttx intermediates
, 2009 [EN] The present invention relates to the synthesis of intermediates that can be used in TTX synthesis and to the preparation thereof.
Noheda Marín, Pedro +3 more
openaire +2 more sources
Astrocytic mGluR5 Regulation of Synaptic Transmission is Activity‐Dependent in Adult Rats
Glia, Volume 74, Issue 8, August 2026.In adulthood, astrocytic mGluR5 increases synaptic efficacy through presynaptic A2ARs. This occurs when a small number of synapses are activated simultaneously. This pathway is abolished when numerous synapses are recruited. ABSTRACT Data accumulated over the last two decades have demonstrated that astrocytes play key roles in the regulation of ...
Sarah Mountadem +18 more
wiley +1 more source
TTX-induced disuse of mammalian skeletal muscle
, 1989 Previous reports of the effects of tetrodotoxin (TTX)-induced muscular disuse have demonstrated alterations in muscle force, speed, and fatiguability that might suggest changes in the quality of contractile proteins.
Panenic, Robert
core
Effect of tetrodotoxin (TTX) on action potential generation.
, 2012 Application of TTX led to a slowing in spontaneous action potential generation in hiPSC-CMs (A) but did not stop AP generation whereas TTX completely abolished AP generation in hESC-CMs at 10 µM concentration (B). Overlay of representative traces display
Xiaowu Sheng (131836) +6 more
core +1 more source