Results 211 to 220 of about 29,634 (242)
Assessing NaV1.7 during tonic firing in pig C-nociceptors. [PDF]
PLoS OneSoares S +4 more
europepmc +1 more source
Ripples in Time and Space Regulate Epileptic Firing in the Hippocampus. [PDF]
Epilepsy CurrStafstrom CE.
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TTX accumulation in pufferfish
Comparative Biochemistry and Physiology Part D: Genomics and Proteomics, 2006Tetrodotoxin (TTX) has been detected in a variety of animals. The finding of TTX in the trumpet shell Charonia sauliae strongly suggested that its origin was its food, a TTX-bearing starfish Astropecten polyacanthus. Since then, the food chain has been consistently implicated as the principal means of TTX intoxication.
Tamao Noguchi +2 more
exaly +3 more sources
Molecular Pharmacology, 2002
Ambroxol has a long history for the treatment of airway diseases because of its beneficial effects on surfactant synthesis and mucus-modifying properties. Some findings, however, point to an additional effect on neuronal signal transduction: ambroxol can suppress reflexes such as the cough or the corneal reflex.
Thomas Weiser
exaly +3 more sources
Ambroxol has a long history for the treatment of airway diseases because of its beneficial effects on surfactant synthesis and mucus-modifying properties. Some findings, however, point to an additional effect on neuronal signal transduction: ambroxol can suppress reflexes such as the cough or the corneal reflex.
Thomas Weiser
exaly +3 more sources
Inactivation of TTX-sensitive and TTX-insensitive sodium channels of rat myoballs
Neuroscience Letters, 1987Myoballs, spherical muscle cell regenerates, have two types of Na+ channels, the adult type with a high sensitivity to the Na+ channel blocker tetrodotoxin (TTX), and the juvenile type with 10 times less TTX sensitivity. The potential dependence of the steady-state inactivation of the Na+ channels (h infinity-curve) was studied in 50 rat myoballs with ...
J P, Ruppersberg, A, Schure, R, Rüdel
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A Mutant of TTX-Resistant Cardiac Sodium Channels with TTX-Sensitive Properties
Science, 1992The cardiac sodium channel α subunit (RHI) is less sensitive to tetrodotoxin (TTX) and saxitoxin (STX) and more sensitive to cadmium than brain and skeletal muscle (μl) isoforms. An RHI mutant, with Tyr substituted for Cys at position 374 (as in μl) confers three properties of TTX-sensitive channels: (i) greater sensitivity to TTX (730-fold); (ii ...
J, Satin +6 more
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Effects of ATP on TTX-sensitive and TTX-resistant sodium currents in rat sensory neurons
Neuroreport, 2001Differential effects of ATP on tetrodotoxin-sensitive (TTX-S) and tetrodotoxin-resistant (TTX-R) sodium currents in rat dorsal root ganglion neurons were studied using the whole-cell variation of path-clamp technique. Currents were evoked by step depolarizations to 0 mV from a holding potential of -80 mV.
J H, Song +4 more
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