Results 61 to 70 of about 127,769 (266)

A Systematic Approach to Identifying Protein-Ligand Binding Profiles on a Proteome Scale [PDF]

, 2008
Identification of protein-ligand interaction networks on a proteome scale is crucial to address a wide range of biological problems such as correlating molecular functions to physiological processes and designing safe and efficient therapeutics.
Lei Xie, Li Xie, Nancy Buchmeier, Philip Bourne   +3 more
core   +2 more sources

New approaches to treating chronic obstructive pulmonary disease with Colla corii asini

Animal Models and Experimental Medicine, EarlyView.
Colla corii asini improves chronic obstructive pulmonary disease (COPD) treatment through anti‐inflammatory, antioxidant, immune‐modulatory, and lung‐nourishing effects, addressing current therapeutic challenges via multitarget mechanisms. Abstract Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death and disability ...
Wenchao Zhang, Siman Sun, Xiaoyu Fan, Jiuming He, Qing Li, Hongtao Jin   +5 more
wiley   +1 more source

Myocarditis following rAd26 and rAd5 vector‐based COVID‐19 vaccine: case report

ESC Heart Failure, 2022
SARS‐CoV‐2 vaccines provide a safe solution with a major impact on reducing the spread of the virus and mild side effects. Research has shown rare cases of myocarditis after mRNA vaccines. This study presents a 29‐year‐old male with chest pain after 48 h
Farah Naghashzadeh, Shadi Shafaghi, Atosa Dorudinia, Seyed Alireza Naji, Majid Marjani, Ahmad Amin, Arezoo Mohamadifar, Sima Noorali, Babak Sharif Kashani   +8 more
doaj   +1 more source

Case‐Based Immunology: B Cells and Systemic Sclerosis Interstitial Lung Disease

Arthritis &Rheumatology, EarlyView.
Interstitial lung disease (ILD) is an important complication of systemic sclerosis (SSc), with high mortality and morbidity. Recent clinical studies in SSc‐ILD have led to US Food and Drug Administration–approved therapies in SSc‐ILD. Importantly, evidence from these studies has been extrapolated to guide management of ILDs of other systemic autoimmune
Nina Goldman, Voon Ong, Christopher P. Denton   +2 more
wiley   +1 more source

A case report on smear-Positive pulmonary tuberculosis with neurofibromatosis type-1

Journal of the Scientific Society, 2023
Neurofibromatosis (NF) is a group of disorders that is caused by a genetic mutation which is dominantly inherited neurogenetic disorder. They are of three types: NF1, NF2, and schwannomatosis. Out of these three, NF1 is the most common.
Khushboo Chavda, Smit Mistry, Cyril Sajan   +2 more
doaj   +1 more source

The state of the cardiovascular system in patients with pulmonary tuberculosis [PDF]

Kazan medical journal, 1984
Over the past two decades, the interest of clinicians in the state of the cardiovascular system in patients with pulmonary tuberculosis has significantly increased, which is associated both with the use of advanced technology, which allows a more in-depth study of hemodynamics, and with the pathomorphosis of tuberculosis.
F. T. Krasnoperov, A. A. Vizel
openaire   +1 more source

Biomass Fuel Use and Cardiac Function in Nepali Women. [PDF]

, 2020
BackgroundExposure to household air pollution (HAP) from cooking with biomass fuel affects billions of people. We hypothesized that HAP from woodsmoke, compared to other household fuels, was associated with adverse cardiovascular outcomes, of which there
Alurkar, Vijay, Balmes, John R, Bates, Michael N, Benziger, Catherine, Hooper, Laura, Kafle, Ramchandra, Kaufman, Joel D, Pope, Karl, Sijali, Tula R, Tiwana, Jasleen   +9 more
core   +2 more sources

HIV infection is associated with elevated biomarkers of immune activation in Ugandan adults with pneumonia. [PDF]

, 2019
IntroductionPneumonia is an important cause of morbidity and mortality in persons living with human immunodeficiency virus (HIV) infection. How immune activation differs among HIV-infected and HIV-uninfected adults with pneumonia is unknown.MethodsThe ...
Byanyima, Patrick, Chang, Emily G, Crothers, Kristina, Davis, J Lucian, Huang, Laurence, Hunt, Peter W, Kaswabuli, Sylvia, Lalitha, Rejani, Lederman, Michael M, Lin, Jue, Moisi, Daniela, Moore, Julia, Musisi, Emmanuel, Sanyu, Ingvar, Sessolo, Abdulwahab, Wang, Richard J, Worodria, William   +16 more
core   +2 more sources

A cooperative release of mitochondrial DNA from platelets and neutrophils drives an interferon signature in systemic sclerosis

Arthritis &Rheumatology, Accepted Article.
Objective Mitochondria are organelles with a hypomethylated circular genome. Mitochondrial DNA (mtDNA) in the systemic circulation has been implicated in inflammation. This study investigates the role of circulating DNA in systemic sclerosis (SSc) and the cellular mechanisms governing its release.
Stavros Giaglis, André N. Tiaden, Simone Häner‐Massimi, Diego Kyburz, Cedric André, Anton Glück, Enrico Ferrero, Stuart Hawtin, Tobias Junt, Ulrich A. Walker   +9 more
wiley   +1 more source

GRADE equity guidelines 4: guidance on how to assess and address health equity within the evidence to decision process [PDF]

, 2017
Objective: The aim of this paper is to provide detailed guidance on how to incorporate health equity within the GRADE (Grading Recommendations Assessment and Development Evidence) evidence to decision process.
Akl, Elie A, Alonso-Coello, Pablo, Briel, Matthias, Eslava-Schmalbach, Javier H, Guyatt, Gordon, Katikireddi, Vittal, Lang, Eddy, Magrini, Nicola, Matovinovic, Elizabeth, Moja, Lorenzo, Morton, Rachael, Pottie, Kevin, Schunemann, Holger, Shea, Beverly, Singh, Jasvinder, Snellman, Alexandra, Stanev, Roger, Thabane, Lehana, Tugwell, Peter, Welch, Vivian   +19 more
core   +1 more source