Results 111 to 120 of about 80,369 (215)

Computational Study on Potentially Active Antibacterial Compounds in Secondary Metabolites of Extremophilic Microorganisms

open access: yesChemistryOpen, Volume 15, Issue 4, April 2026.
This study employed density functional theory (DFT) and conceptual DFT (CDFT) to calculate the structures and properties of potential antibacterial compounds derived from 16‐membered lactone ring‐containing secondary metabolites of extremophiles, as well as midecamycin.
Dilong Li   +6 more
wiley   +1 more source

Social aspects multi-drug resistant tuberculosis

open access: yesБюллетень сибирской медицины, 2012
The comparative analysis of features of clinical symptoms, spectrum and the importance of burdening medico-social factors of a tuberculosis of lungs with primary MDR М.
O. V. Filinyuk   +6 more
doaj   +1 more source

Thin-layer agar for detection of resistance to rifampicin, ofloxacin and kanamycin in Mycobacterium tuberculosis isolates [PDF]

open access: yes, 2009
BACKGROUND: In low-income countries there is a great need for economical methods for testing the susceptibility of Mycobacterium tuberculosis to antibiotics. OBJECTIVE: To evaluate the thin-layer agar (TLA) for rapid detection of resistance to rifampicin
Almeida, P   +7 more
core   +1 more source

Comprehensive Analysis of Structure Activity Relationships in Quinoxaline Derivatives Covering Antimicrobial Applications

open access: yesChemistrySelect, Volume 11, Issue 14, 13 April 2026.
ABSTRACT Antimicrobial resistance (AMR) has emerged as one of the most critical global health challenges, undermining the clinical efficacy of existing antibiotics and threatening modern therapeutic strategies. The ongoing misuse and overuse of antimicrobial agents have accelerated the evolution of resistant bacterial strains and parasites ...
Subham Kumar Vishwakarma   +2 more
wiley   +1 more source

Bacterial Extracellular Vesicles in Biomedical Research and Clinical Translation

open access: yesMicrobial Biotechnology, Volume 19, Issue 4, April 2026.
Bacterial membrane vesicle biomedical applications. ABSTRACT Bacterial Extracellular Vesicles (bEVs) are lipid (single‐ or double‐bilayer) nanostructures secreted by virtually all bacteria that play fundamental roles in intercellular communication and have emerged as powerful, multifunctional tools in biomedicine. Their intrinsic ability to encapsulate
Alejandro Arce‐Rodríguez   +2 more
wiley   +1 more source

From Lake Victoria to the Tap: Antibiotic Resistance and Pathogenic Contamination of Kisumu City Water Supply and Wastewater Network

open access: yesTropical Medicine &International Health, Volume 31, Issue 4, Page 547-559, April 2026.
ABSTRACT Waterborne diseases and antimicrobial resistance (AMR) pose mounting public health threats across sub‐Saharan Africa, particularly in rapidly urbanising regions dependent on untreated or poorly treated surface waters. This study applied shotgun metagenomic sequencing to characterise microbial communities, virulence factors and antibiotic ...
Oleg N. Reva   +8 more
wiley   +1 more source

Determinants of multidrug-resistant tuberculosis among adults undergoing treatment for tuberculosis in Tigray Region, Ethiopia: a case–control study

open access: yesBMJ Open Respiratory Research
Background Multidrug-resistant tuberculosis is a type of tuberculosis that is resistant to at least the first-line antituberculosis drugs namely, rifampicin and isoniazid. However, most of these studies were limited only to a single hospital.
Kidane Zereabruk   +6 more
doaj   +1 more source

Linezolid-containing regimens for the treatment of drug-resistant tuberculosis in South African children.

open access: yes, 2012
BACKGROUND: Treatment options for drug-resistant tuberculosis (DR-TB) are limited. Linezolid has been successfully used to treat DR-TB in adults, but there are few case reports of its use in children for TB.
Hallbauer, UM   +4 more
core   +1 more source

Multidrug-resistant tuberculosis.

open access: yesAdvances in internal medicine, 1995
In 1993, the World Health Organization declared tuberculosis a global emergency. Tuberculosis is the leading cause of death attributable to a single infectious pathogen. One-third of the world's population are at risk of developing the disease. In countries confronted with the human immunodeficiency virus (HIV) epidemic, the overlap of these two ...
S K, Lee   +3 more
openaire   +3 more sources

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