Results 111 to 120 of about 1,086,070 (250)

Improved diagnosis of pleural tuberculosis using the microscopic- observation drug-susceptibility technique.

, 2008
Tests for pleural tuberculosis are insensitive and expensive. We compared nonproprietary microscopic-observation drug-susceptibility (MODS) culture with Löwenstein-Jensen culture for evaluation of pleural specimens.
Tovar, Marco, Escombe, A Rod, Santillan, Carlos, Moore, David AJ, Siedner, Mark J, Evans, Carlton A, Valencia, Teresa, Caviedes, Luz, Gilman, Robert H, Jave, Oswaldo   +9 more
core   +1 more source

Targeting a Myeloid–Regulatory B Cell Network Reverses Immune Paralysis in Periprosthetic Joint Infections

Advanced Science, Volume 13, Issue 51, 14 September 2026.
Periprosthetic joint infection establishes a sophisticated immunosuppressive network between CXCR4+ PMN‐MDSCs and Bregs, inducing profound CD8+ T cell paralysis. Alendronate effectively disrupts this CXCR4+ PMN‐MDSC–Breg axis by targeting STAT3, thereby restoring local immune surveillance.
Jintao Wu, Shutao Zhang, Yumin Lin, Juyang Jiao, Zhiwei Fu, Qimin Hong, Ziyi Zhao, Xinhua Qu, Fei Su, Bing Yue   +9 more
wiley   +1 more source

Primary multidrug-resistant tuberculosis and its control implications in the State of Amazonas, Brazil: report of 3 cases

Revista da Sociedade Brasileira de Medicina Tropical, 2012
The occurrence of tuberculosis with first-line multidrug resistance leads to the use of alternative medications, often at higher costs, longer treatment periods, and greater clinical complexity.
Marlucia Silva Garrido, Anette Chrusciak Talhari, Irineide Assumpção Antunes, Joycenea da Silva Matsuda, Etelvina das Graças Zaranza, Flor Ernestina Martinez-Espinosa, Samira Bührer-Sékula   +6 more
doaj   +1 more source

MT‐RNR1 genotype testing for preventing aminoglycoside‐mediated ototoxicity: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, Volume 92, Issue 9, Page 3002-3011, September 2026.
Aminoglycosides are broad‐spectrum antibiotics used in the management of severe infections. Aminoglycosides are associated with nephrotoxicity and ototoxicity. Although dosing strategies such as once‐daily administration and therapeutic drug monitoring have reduced the incidence of nephrotoxicity, ototoxicity remains unpredictable and may occur at ...
John H. McDermott, Sian Hilton, Cinzia Dello Russo, Nicola Booth, Simon Drysdale, Philip Howard, Stephen Hughes, Mallinath Chakraborty, Helen McDevitt, Charlotte Alston, Maya Desai, Mike Beadsworth, Adam Reynolds, Serim Min, Katherine Payne, Munir Pirmohamed, William G. Newman   +16 more
wiley   +1 more source

PhyTB: Phylogenetic tree visualisation and sample positioning for M. tuberculosis. [PDF]

, 2015
BACKGROUND: Phylogenetic-based classification of M. tuberculosis and other bacterial genomes is a core analysis for studying evolutionary hypotheses, disease outbreaks and transmission events.
Pain, Arnab, Mohareb, Fady R, Taane G Clark, Campino, Susana, Nick Furnham, Clark, Taane G., Benavente, Ernest D., McNerney, Ruth, Glynn, Judith R., Ruth McNerney, Glynn, Judith R, Furnham, Nick, Fady R Mohareb, Benavente, Ernest D, Susana Campino, Francesc Coll, Judith R Glynn, Mohareb, Fady R., Ernest D Benavente, Arnab Pain, Coll, Francesc, Clark, Taane G   +21 more
core   +2 more sources

Limited Scope of Shorter Drug Regimen for MDR TB Caused by High Resistance to Fluoroquinolone

Emerging Infectious Diseases, 2019
Resistance to second-line tuberculosis drugs for patients with multidrug-resistant tuberculosis has emerged globally and is a potential risk factor for unfavorable outcomes of shorter duration drug regimens.
Pravin K. Singh, Amita Jain
doaj   +1 more source

Recent Advances in Microwave and Ultrasound Assisted Synthesis of Quinoline Derivatives as Anticancer Agents

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Green microwave‐ and ultrasound‐assisted synthesis enables the rapid, sustainable preparation of quinoline‐based anticancer agents with improved reaction efficiency, higher yields, and enhanced biological activity. ABSTRACT Quinoline derivatives represent a privileged class of heterocyclic compounds with remarkable structural diversity and broad ...
Rohit Pal, Gurubasavaraja Swamy Purawarga Matada, Ghanshyam Teli, Manjushree B V, Vipin K. Pandey, Shourya Pratap   +5 more
wiley   +1 more source

M. tuberculosis genotypic diversity and drug susceptibility pattern in HIV-infected and non-HIV-infected patients in northern Tanzania. [PDF]

, 2007
Contains fulltext : 53004.pdf (Publisher’s version ) (Open Access)BACKGROUND: Tuberculosis (TB) is a major health problem and HIV is the major cause of the increase in TB.
Boeree, M.J., Sola Christophe, Martin Boeree, Kibiki, Gibson S, Mulder, Bert, van Soolingen Dick, Jessica L de Beer, de Beer Jessica L, Bert Mulder, Dolmans, Wil M V, Mulder, B., Boeree Martin, Christophe Sola, van der Zanden, Adri G M, Dolmans Wil MV, Beer, J.L. de, Dolmans, W.M.V., Kibiki, G.S., Dick van Soolingen, Mulder Bert, Boeree, Martin, de Beer, Jessica L, Soolingen, D. van, Sam, N., Kibiki Gibson S, van der Zanden Adri GM, Noel Sam, van Soolingen, Dick, Sam Noel, Sola, Christophe, Adri GM van der Zanden, Gibson S Kibiki, Zanden, A.G. van der, Sola, C., Wil MV Dolmans, Sam, Noel   +35 more
core   +2 more sources

Social aspects multi-drug resistant tuberculosis

Бюллетень сибирской медицины, 2012
The comparative analysis of features of clinical symptoms, spectrum and the importance of burdening medico-social factors of a tuberculosis of lungs with primary MDR М.
O. V. Filinyuk, O. I. Urazova, Ye. V. Nekrasov, L. N. Buinova, O. V. Kolokolova, I. G. Felker, O. Yu. Khristenko   +6 more
doaj   +1 more source

A Thiosemicarbazone Schiff Base and Its Titanium(IV) Complexes: Spectral Analysis, DFT Studies, and Biological Evaluation

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
DFT computations are used to analyze the electronic structure, stability, and reactivity profiles of a new Schiff base ligand and its Ti(IV) complexes and are characterized by elemental analysis, IR, 1H NMR, 13C NMR, and mass spectrometry and screened for antimicrobial activities against E. coli, S. aureus, ESBL, MRSA, Mtb, A.
Priyanka Ghanghas, Anshul Yadav, Astha Kamboj, Anita Choudhary, Manjinder Kour, Dinesh Kumar, Kavita Poonia   +6 more
wiley   +1 more source