Results 101 to 110 of about 1,086,070 (250)

Targeting homologous recombination repair to potentiate fluoroquinolone efficacy in Mycobacterium abscessus

mLife, EarlyView.
Shuai Wang, Md Shah Alam, Buhari Yusuf, Jingran Zhang, Ziwen Lu, Xiaofan Zhang, H. M. Adnan Hameed, Mst. Sumaia Khatun, Chunyu Li, Lijie Li, Aleksey A. Vatlin, Aweke M. Belachew, Xirong Tian, Yamin Gao, Cuiting Fang, Rogers P. Zhang, Jun Li, Xinyue Wang, Liqiang Feng, Li Wan, Tianyu Zhang   +20 more
wiley   +1 more source

A New Sustainable Approach to Antibiotic Resistance: Development of bis‐Quaternary Ammonium Salts From 2,4,6‐Trichloro‐1,3,5‐Triazine

ChemMedChem, Volume 21, Issue 17, 14 September 2026.
Antibiotics improved human life, but bacterial resistance makes surfaces and packaging disinfection critical. Quaternary ammonium salts (QAS) represent a possible alternative. In this work, new bis‐cationic QAS from 2,4,6‐trichloro‐1,3,5‐triazine (bis‐TQAS) were synthesized, showing excellent inhibition against Klebsiella pneumoniae, Escherichia coli ...
Rachele Rampazzo, Arianna De Luca, Manuela Facchin, Patrizio Raffa, Andrea Gattolin, Valentina Beghetto   +5 more
wiley   +1 more source

Tuberculosis in antiretroviral treatment services in resource-limited settings: addressing the challenges of screening and diagnosis. [PDF]

, 2011
The high burden of tuberculosis (TB) among patients accessing antiretroviral treatment (ART) services in resource-limited settings is a major cause of morbidity and mortality and is associated with nosocomial transmission risk.
Lawn, Stephen D, Robin Wood, Wood, Robin, Stephen D. Lawn   +3 more
core   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, Volume 38, Issue 51, 11 September 2026.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Survival of Civilian and Prisoner Drug-Sensitive, Multi- and Extensive Drug- Resistant Tuberculosis Cohorts Prospectively Followed in Russia [PDF]

, 2011
This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Rutterford, CM, Shakhmistova Anastasiya, Nadezhda Malomanova, Malomanova Nadezhda, Nikolayevskyy, V, Malomanova, N, Ignatyeva, O, Rutterford Clare M., Mironova Svetlana, Yulia Chinkova, Mironova, S, Anastasiya Shakhmistova, Vladyslav Nikolayevskyy, Francis A. Drobniewski, Balabanova Yanina, Irina Kontsevaya, Drobniewski, FA, Chinkova, Y, Kontsevaya, I, Olga Ignatyeva, Clare M Rutterford, Chinkova Yulia, Francis A Drobniewski, Balabanova, Y, Shakhmistova, A, Fedorin, I, Yanina Balabanova, Ignatyeva Olga, Nikolayevskyy Vladyslav, Ivan Fedorin, Fedorin Ivan, Svetlana Mironova, Drobniewski Francis A., Clare M. Rutterford, Kontsevaya Irina   +34 more
core   +2 more sources

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

Advanced Science, Volume 13, Issue 50, 7 September 2026.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai, Hongming Huang, Xudong Hang, Shanwei Hu, Qian Tong, Jingchen Xu, Jia Jia, Hongkai Bi   +7 more
wiley   +1 more source

Acute glomerulonephritis in a child with multidrug-resistant tuberculosis and multibacillary leprosy

, 2011
A 10-year-old boy from Papua New Guinea with multidrug-resistant tuberculosis and multibacillary leprosy developed acute glomerulonephritis while being treated as an inpatient at Thursday Island Hospital in the Torres Strait, Queensland.
Jones, Samuel P., Furlong, Timothy J., Parish, Shaun T., Kippin, Alexander N., McIver, Lachlan J.   +4 more
core   +1 more source

Primary multidrug resistant tuberculosis

Lung India, 2007
A 37-year old man presented at our institution with back pain, low-grade fever and weight-loss. X-ray of chest (postero-anterior view) showed multiple opacities with erosion of right 2nd and left 6th ribs.
Sarkar Supriya, Maity G, Mukhopadhyay K, Acharyya Biplab, Ghoshal A   +4 more
doaj  

Exploring health care providers’ engagement in prevention and management of multidrug resistant Tuberculosis and its factors in Hadiya Zone health care facilities: qualitative study

BMC Health Services Research
Background Engagement of healthcare providers is one of the World Health Organization strategies devised for prevention and provision of patient centered care for multidrug resistant tuberculosis.
Bereket Aberham Lajore, Yitagesu Habtu Aweke, Samuel Yohannes Ayanto, Menen Ayele   +3 more
doaj   +1 more source

Conformational Snapshots of CydDC in a Native Lipid Bilayer Coupling Heme Transport to Antibiotic Resistance

Advanced Science, Volume 13, Issue 50, 7 September 2026.
Phylogenetic and biochemical analyses of the heme transporter CydDC reveal its functional conservation throughout bacterial evolution and demonstrate its unique asymmetric allosteric mechanism. Furthermore, impairment of CydDC function directly affects bacterial antibiotic resistance and likely compromises antibiotic efficacy through drug efflux.
Lili Yang, Changbin Zhang, Mengyuan Lyu, Yongbo Luo, Jierou Zhang, Yujiao Chen, Lintao Luo, Wen Qiao, Xiangyangpeng Li, Yu Zhou, Zhongling Wei, Yuling Xiao, Qian Niu, Juan Zhou, Guanglin He, Binwu Ying, Zhaoming Su, Hao Chen, Xiaodi Tang, Haohao Dong   +19 more
wiley   +1 more source