Results 121 to 130 of about 1,086,070 (250)

Multidrug-Resistant Tuberculosis [PDF]

New England Journal of Medicine, 2012
Mel, Spigelman, Carolyn, Compton, Jan, Gheuens   +2 more
openaire   +4 more sources

Tuberculosis Misdiagnosed as Bronchogenic Carcinoma: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT The patient, a 77‐year‐old male smoker, presented to the Emergency Department with dyspnea, cough, fever, night sweats, and 12 kg weight loss, initially suggesting COPD or lung cancer. Chest CT revealed a right upper lobe mass, pleural effusion, and lymphadenopathy, prompting suspicion of malignancy.
Pejman Hosseinzadeh, Sara Samadi, Shirin Taraz Jamshidi, Sayed Mortaza Fayez, Mahnaz Mozdourian   +4 more
wiley   +1 more source

Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden

ChemFoodChem, Volume 2, Issue 3, September 2026.
ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley   +1 more source

Hematological Profiles of Pulmonary Tuberculosis and Multi‐Drug‐Resistant Tuberculosis Patients at Debre Tabor Comprehensive Specialized Hospital, North‐Central Ethiopia: A Comparative Cross‐Sectional Study

Health Science Reports
Background and Aims Tuberculosis is a major infectious disease that affects hematological profiles. However, limited data assess changes in hematological profiles among patients with pulmonary and multidrug‐resistant tuberculosis.
Ayenew Berhan, Bekele Sharew, Andargachew Almaw, Shewaneh Damtie, Biruk Legese, Mulat Erkihun, Ayenew Assefa, Birhanemaskal Malkamu, Getu Abeje, Birhanu Getie, Yenealem Solomon   +10 more
doaj   +1 more source

Determinants of multidrug-resistant tuberculosis among adults undergoing treatment for tuberculosis in Tigray Region, Ethiopia: a case–control study

BMJ Open Respiratory Research
Background Multidrug-resistant tuberculosis is a type of tuberculosis that is resistant to at least the first-line antituberculosis drugs namely, rifampicin and isoniazid. However, most of these studies were limited only to a single hospital.
Kidane Zereabruk, Tensay Kahsay, Hiyab Teklemichael, Woldu Aberhe, Abrha Hailay, Guesh Mebrahtom, Gebrewahd Bezabh   +6 more
doaj   +1 more source

Stereodivergent Synthesis of C5‐α‐Substituted Linezolid Derivatives From D‐Mannitol and Structure–Antibacterial Activity Evaluation

Chirality, Volume 38, Issue 9, September 2026.
A stereodivergent route from D‐mannitol enables access to enantiopure C5‐α‐substituted linezolid analogues with full configurational control. Biological evaluation reveals that α‐substitution abolishes antibacterial activity irrespective of stereochemistry, establishing a strict steric limitation at C5 and highlighting the dominant role of substituent ...
José A. Gálvez, Laura Sanz‐Asensio, Ramón Badorrey, Jesús Gonzalo‐Asensio   +3 more
wiley   +1 more source

Tuberculosis in Sudan: A Comprehensive Narrative Review of Epidemiological Trends, Diagnosis, Drug Resistance, Challenges, and Data Gaps

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims This narrative review aims to provide a comprehensive overview of tuberculosis (TB) in Sudan, focusing on prevalence, drug resistance patterns, and associated challenges while identifying knowledge gaps in scientific research and data needed for effective management.
Mohammad Azhar Kamal, Hisham N. Altayb, Shima M. Abdulgader, Ehssan Moglad   +3 more
wiley   +1 more source

Management of Refractory and Difficult‐To‐Treat Inflammatory Bowel Disease: An Expert Opinion Review

JCC Plus, Volume 1, Issue 5, September 2026.
This expert opinion offers a practical framework for refractory and difficult‐to‐treat IBD: confirm inflammation objectively, distinguish pharmacologic from structural and functional disease, and then escalate. Across ten clinical questions, the evidence is often limited to case series, and the resulting statements are identified as expert opinion ...
Filiz Akyuz, Oguz Kagan Bakkaloglu, Nalan Gulsen Unal, Ismail Hakki Kalkan, Mehmet Arhan, Ibrahim Hatemi, Taylan Kav, Murat Toruner, Hale Akpinar, Ahmet Tezel, Aykut Ferhat Celik   +10 more
wiley   +1 more source

A new roadmap for childhood tuberculosis

The Lancet Global Health, 2014
Colleen D Acosta, Valiantsin Rusovich, Anthony D Harries, Sevim Ahmedov, Martin van den Boom, Masoud Dara   +5 more
doaj   +1 more source

Semi‐Mechanistic Joint Population Pharmacokinetic Modeling of the Novel Antituberculosis Drug Sorfequiline and Its Metabolite M3 in Healthy Volunteers

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 9, September 2026.
ABSTRACTSorfequiline is a novel diarylquinoline in development for treatment of tuberculosis. In vitro data suggest metabolism via CYP3A4, carrying the potential for presystemic metabolism and drug–drug interactions. Its major metabolite, M3, is pharmacologically active.
Jose M. Calderin, Jerry Nedelman, David H. Salinger, Thanakorn Vongjarudech, Paolo Denti, Elin M. Svensson   +5 more
wiley   +1 more source