Results 81 to 90 of about 1,086,070 (250)

Pharmacotherapy for multidrug resistant tuberculosis.

Journal of pharmacology & pharmacotherapeutics, 2012
The current global concern in the treatment of tuberculosis (TB) is the emergence of resistance to the two most potent drugs namely, isoniazid and rifampicin. Emergence of multidrug resistance tuberculosis (MDR-TB) is now a health problem faced by most of the developing countries as well as developed countries across the globe.
Chhabra, Naveen, Aseri, M. L., Dixit, Ramakant, Gaur, S.   +3 more
openaire   +2 more sources

The Paediatric BCG Vaccine Century: From Historical Success to Future Innovations

Acta Paediatrica, EarlyView.
ABSTRACT Aim The tuberculosis (TB) vaccine, Bacille‐Calmette‐Guérin (BCG), protects infants against severe forms of primary TB. Yet, it does not protect against pulmonary reactivation TB in adults. Methods A literature review was conducted between 1st January and 28th February 2025 using PubMed, Google Scholar and reports of the World Health ...
Stefan H. E. Kaufmann
wiley   +1 more source

Evaluation of tuberculosis diagnostics: establishing an evidence base around the public health impact. [PDF]

, 2011
The limitations of existing tuberculosis diagnostic tools are significantly hampering tuberculosis control efforts, most noticeably in areas with high prevalence of human immunodeficiency virus (HIV) infection and antituberculosis drug resistance ...
Newell, Marie-Louise, Graham S. Cooke, Marie-Louise Newell, Cooke, Graham S, Peter Godfrey-Faussett, Richard J. Lessells, Lessells, Richard J, Godfrey-Faussett, Peter   +7 more
core   +1 more source

Patterns of Drug Resistance, Drug Resistance Conferring Mutations and Genomic DNA Methylation Revealed in Mycobacterium tuberculosis From South Africa

Tropical Medicine &International Health, EarlyView.
ABSTRACT Tuberculosis remains a major public health threat globally, with drug‐resistant strains undermining treatment efficacy. We analyzed 126 Mycobacterium tuberculosis (M. tuberculosis) isolates with diverse drug resistance spectra and selected 35 for whole genome sequencing (WGS) using Illumina NextSeq, SMRT PacBio Onso and SMRT PacBio Revio ...
Unarine Matodzi, Awelani Mutshembele, Eric Mensah, Dillon Muzondiwa, Ndivhuho A. Makhado, Oleg N. Reva   +5 more
wiley   +1 more source

Being safe, feeling safe, and stigmatizing attitude among primary health care staff in providing multidrug-resistant tuberculosis care in Bantul District, Yogyakarta Province, Indonesia

Human Resources for Health, 2019
Introduction Patient-centered care approach in multidrug-resistant tuberculosis care requires health worker safety that covers both being safe and feeling safe to conduct the services. Stigma has been argued as a barrier to patient-centered care. However,
Ari Probandari, Hary Sanjoto, Melani Ratih Mahanani, Luthfi Azizatunnisa, Sampir Widayati   +4 more
doaj   +1 more source

Axial Connectivity of the Lung Microbiome: A Review of Interorgan Crosstalk

Comprehensive Physiology, Volume 16, Issue 5, October 2026.
The human microbiome mediates immune homeostasis and metabolic signaling across organs. Beyond the gut‐lung axis, crosstalk between the lung and other organ systems is less recognized. This review assesses the axial connectivity of the lung microbiome across the gut, brain, skin, heart, kidney, and liver.
Mathangi Palanivel, Jayanth Kumar Narayana, Sanjay H. Chotirmall   +2 more
wiley   +1 more source

RESULTS OF CHEMOTHERAPY IN PATIENTS WITH MULTIDRUG-RESISTANT TUBERCULOSIS IN THE REGIONS OF THE RUSSIAN FEDERATION

Туберкулез и болезни лёгких, 2014
The paper analyzes the results of treatment in 5,396 patients with multidrug-resistant tuberculosis who were treated in the regions of the Russian Federation under the Global Fund Round 4 project based on the recommended World Health Organization ...
V. V. Testov, S. A. Sterlikov, I. A. Vasilyeva, V. V. Erokhin, T. Ch. Kesaeva   +4 more
doaj  

Effect of Green‐Synthesized Silver Nanoparticles From Nepeta pogonosperma and Astrodaucus persicus on the Reduction of Bap Gene Expression in Strong Biofilm‐Producing Acinetobacter baumannii Clinical Isolates

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Green‐synthesized silver nanoparticles from Nepeta pogonosperma and Astrodaucus persicus significantly inhibit biofilm formation and downregulate bap gene expression in multidrug‐resistant clinical isolates of Acinetobacter baumannii. This eco‐friendly approach offers a promising strategy to combat antimicrobial resistance.
Maedeh Kakavan, Mehrdad Gholami, Mohammad Ahanjan, Mohammad Ali Ebrahimzadeh, Abolfazl Hossein Nataj, Tahoora Mousavi, Hamid Reza Goli   +6 more
wiley   +1 more source

Issues of Tuberculosis Drug-Resistance in Kharkiv Region and in Ukraine

Infusion & Chemotherapy, 2019
Background. Multidrug-resistant tuberculosis and extensively drug-resistant tuberculosis remain severe epidemic problems in the world. That’s why the purpose of our study was to investigate the dynamics of the incidence of multidrug-resistant and ...
O.S. Shevchenko, O.O. Pohorielova
doaj   +1 more source

Molecular Diagnostics for WHO Priority Bacterial Pathogens: A Bibliometric Mapping of Diagnostic Platforms, Resistance Markers, and Antimicrobial Resistance Research Trends

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
This bibliometric mapping of 1746 publications (2000–2025) charts molecular diagnostics for WHO priority bacterial pathogens across platforms, targets, and resistance markers. Conventional PCR/NAAT and whole‐genome sequencing emerge as complementary core platforms, and the field evolves from targeted pathogen detection into an AMR‐centered ...
Selahattin Ünlü
wiley   +1 more source