Results 61 to 70 of about 39,720 (193)

Assessment of Cattle Owners’ Knowledge, Attitudes and Practices Regarding Bovine Tuberculosis in the Eastern Cape Province, South Africa

Public Health Challenges, Volume 5, Issue 3, September 2026.
Bovine tuberculosis remains a major livestock and zoonotic threat in South Africa. This study assessed knowledge, attitudes and practices among communal cattle farmers in the Eastern Cape. Findings revealed low awareness, poor preventive practices, minimal testing and resistance to control measures, underscoring the need for targeted education ...
Effort Maguta, Anita Michel, Ishmael Festus Jaja   +2 more
wiley   +1 more source

Pharmacotherapy for multidrug resistant tuberculosis.

Journal of pharmacology & pharmacotherapeutics, 2012
The current global concern in the treatment of tuberculosis (TB) is the emergence of resistance to the two most potent drugs namely, isoniazid and rifampicin. Emergence of multidrug resistance tuberculosis (MDR-TB) is now a health problem faced by most of the developing countries as well as developed countries across the globe.
Chhabra, Naveen, Aseri, M. L., Dixit, Ramakant, Gaur, S.   +3 more
openaire   +2 more sources

Clinical Features and Treatment Outcomes of Patients with Drug-Resistant and Drug-Sensitive Tuberculosis: A Historical Cohort Study in Porto Alegre, Brazil.

PLoS ONE, 2016
PurposeTo evaluate the clinical features and treatment outcomes of patients with pulmonary tuberculosis, stratified by level of drug resistance.MethodsThis was a historical cohort study based on data from the II National Anti-Tuberculosis Drug Resistance
Vania Celina Dezoti Micheletti, Afrânio Lineu Kritski, José Ueleres Braga   +2 more
doaj   +1 more source

Underexplored Ligand‐Binding Features of FabI From Staphylococcus aureus and Escherichia coli: A Comparative Pharmacophoric Modeling and Surface Mapping Approach

ChemMedChem, Volume 21, Issue 15, 14 August 2026.
Antimicrobial resistance highlights the urgent need for novel FabI inhibitors. Using an integrated computational approach combining ConPhar pharmacophore modeling, FTMap surface mapping, and PLIP interaction profiling across experimental structures and structures from MD simulations, we identified a conserved binding core (Y156/Y157, A95) and ...
Pedro Tenório T. F. Leite, Lucas H. S. Ocarino, Gabriel C. Veríssimo, Philipe O. Fernandes, Dara Fernanda Pereira, Fernanda Kelly M. e Oliveira, Alberto Marbán‐González, José L. Medina‐Franco, Mateus Sá M. Serafim, Thales Kronenberger, Vinícius G. Maltarollo   +10 more
wiley   +1 more source

Factors associated with multidrug-resistant tuberculosis

IMC Journal of Medical Science, 2009
This case control study was conducted in selected centers of Dhaka City from March to July 2008 to determine the association of multidrug-resistant tuberculosis with the attributes related to treatment and socio-economic condition of tuberculosis ...
Md Nurul Amin, Md Anisur Rahman, Meerjady Sabrina Flora, Md Abul Kalam Azad   +3 more
doaj  

Impact of COVID-19 on diagnosis of tuberculosis, multidrug-resistant tuberculosis, and on mortality in 11 countries in Europe, Northern America, and Australia. A Global Tuberculosis Network study. [PDF]

Int J Infect Dis, 2023
Nalunjogi J, Mucching-Toscano S, Sibomana JP, Centis R, D'Ambrosio L, Alffenaar JW, Denholm J, Blanc FX, Borisov S, Danila E, Duarte R, García-García JM, Goletti D, Ong CWM, Rendon A, Thomas TA, Tiberi S, van den Boom M, Sotgiu G, Migliori GB, Global Tuberculosis Network.   +20 more
europepmc   +1 more source

Clinical guideline highlights for the hospitalist: Updates on the treatment of drug‐susceptible and drug‐resistant tuberculosis

Journal of Hospital Medicine, EarlyView.
Allison Stickles, Anna Poston‐Blahnik, Elizabeth Schlaudecker, Moises Huaman   +3 more
wiley   +1 more source

Adverse events in bedaquiline‐ and pretomanid‐based regimens for drug‐resistant tuberculosis from trial, implementation and pharmacovigilance studies

British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2607-2623, August 2026.
Abstract The availability of safety data, particularly concerning adverse events (AEs) associated with the new shorter regimen for drug‐resistant tuberculosis (TB) containing a bedaquiline–pretomanid‐based regimen, is still limited. This systematic review aims to provide a comprehensive and updated analysis of AEs related to this new regimen by ...
Nisa Maria, Annisa Lazuardi Larasati, Indri Yuliani Hamdani, Jin‐Gun Cho, Jan‐Willem C. Alffenaar   +4 more
wiley   +1 more source

Combination of Oral Doxycycline and Rifampin for Pan‐Drug Resistant Klebsiella pneumoniae Infection: A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Pan‐drug resistant Klebsiella pneumoniae is a major therapeutic challenge, particularly when standard last‐line agents are unavailable or contraindicated. We report a 45‐year‐old man with multifocal osteomyelitis and persistent purulent wound discharge despite broad‐spectrum antibiotics, repeated debridement, and two sequential amputations ...
Ali Akbar Heydari, Sepideh Elyasi, Farshad Abedi   +2 more
wiley   +1 more source

Multidrug and extensively drug-resistant tuberculosis from a general practice perspective

Infection and Drug Resistance, 2010
BM Yashodhara1, Choo Beng Huat1, Lakshmi Nagappa Naik1, Shashikiran Umakanth2, Manjunatha Hande2, Joseph M Pappachan31Department of Medicine, Melaka Manipal Medical College, Melaka, India; 2Department of Medicine, Kasturaba Medical College, Manipal ...
BM Yashodhara, Choo Beng Huat, Lakshmi Nagappa Naik, et al   +3 more
doaj