Results 51 to 60 of about 1,086,070 (250)

Enhanced strategies for cuproptosis‐like death in bacterial infection treatment

open access: yesBMEMat, EarlyView.
This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang   +7 more
wiley   +1 more source

Multidrug resistant pulmonary tuberculosis treatment regimens and patient outcomes: an individual patient data meta-analysis of 9,153 patients. [PDF]

open access: yes, 2012
Treatment of multidrug resistant tuberculosis (MDR-TB) is lengthy, toxic, expensive, and has generally poor outcomes. We undertook an individual patient data meta-analysis to assess the impact on outcomes of the type, number, and duration of drugs used ...
Neel Gandhi (139419)   +450 more
core   +2 more sources

Gut microbiota-driven immunomodulation in tuberculosis: targeting dysbiosis to overcome drug resistance

open access: yesFrontiers in Immunology
Tuberculosis (TB) remains a major global health threat, hampered by the escalating prevalence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains.
Qi Nie   +35 more
doaj   +1 more source

Health system factors influencing management of multidrug-resistant tuberculosis in four European Union countries - learning from country experiences

open access: yesBMC Public Health, 2017
Background In the European Union and European Economic Area only 38% of multidrug-resistant tuberculosis patients notified in 2011 completed treatment successfully at 24 months’ evaluation.
Gerard de Vries   +10 more
doaj   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

open access: yesBMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng   +4 more
wiley   +1 more source

Linezolid-containing regimens for the treatment of drug-resistant tuberculosis in South African children.

open access: yes, 2012
BACKGROUND: Treatment options for drug-resistant tuberculosis (DR-TB) are limited. Linezolid has been successfully used to treat DR-TB in adults, but there are few case reports of its use in children for TB.
Rose, PC   +4 more
core   +1 more source

New drugs and vaccines for drug-resistant Mycobacterium tuberculosis infections [PDF]

open access: yes, 2008
Tuberculosis remains the most common cause of death due to a single infective organism. Despite the availability of a vaccine and chemotherapeutic options, the global disease burden remains relatively unaffected.
Willcox, Benjamin   +12 more
core   +1 more source

Linezolid-induced black hairy tongue in a patient with multidrug-resistant tuberculosis: A case report

open access: yesScience Progress, 2021
The revised World Health Organization guidelines on multidrug-resistant tuberculosis include linezolid in the core drugs group. Consequently, the use of linezolid for patients with multidrug-resistant tuberculosis is increasing.
Jaemin Lee   +4 more
doaj   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

open access: yesBMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim   +9 more
wiley   +1 more source

Early and efficient detection of Mycobacterium tuberculosis in sputum by microscopic observation of broth cultures. [PDF]

open access: yes, 2013
Early, efficient and inexpensive methods for the detection of pulmonary tuberculosis are urgently needed for effective patient management as well as to interrupt transmission. These methods to detect M. tuberculosis in a timely and affordable way are not
Benson R Kidenya   +30 more
core   +2 more sources

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