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Enhanced strategies for cuproptosis‐like death in bacterial infection treatment
BMEMat, EarlyView.This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract
Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.Wenqi Wang, Bolong Xu, Ruiyuan Zhu, Hengshuo Gui, Tian Xia, Shaokai Liu, Huiyu Liu, Xianwen Wang +7 morewiley +1 more sourceMultidrug resistant pulmonary tuberculosis treatment regimens and patient outcomes: an individual patient data meta-analysis of 9,153 patients. [PDF]
, 2012 Treatment of multidrug resistant tuberculosis (MDR-TB) is lengthy, toxic, expensive, and has generally poor outcomes. We undertook an individual patient data meta-analysis to assess the impact on outcomes of the type, number, and duration of drugs used ...Neel Gandhi (139419), Joey Lancaster (139471), Robert van Altena (139571), Ponce-de-Leon, A, Van der Werf Tjip S., Timothy H. Holtz (139443), Shim, TS, Falzon, Dennis, Sarah Royce, Flanagan, K, Mario H Vargas, Lia D'Ambrosio, Viiklepp, Pirett, Jae-Joon Yim (139591), Marcos Burgos (139374), Viiklepp Pirett, Burgos, M, Tae Sun Shim, Matthew J Strand, Hollm Delgado MG,, Ghandi, Neel, Chi Chiu Leung, Matthew J. Strand (139566), Ahuja, Shama D., Dung Nguyen Huy, Banerjee, Rita, Gandhi, N, Riekstina Vija, Yim, J-J, Maria I D Quelapio, Dennis Falzon, Jarlsberg, Leah G., Martie Van der Walt (139575), Jamie N. Bayona (139365), Chen-Yuan Chiang (139384), Rita Banerjee (139360), Iseman, Michael D., van Altena, Robert, Burgos, Marcos V., D'Ambrosio, Lia, Bayona, J N, Madhukar Pai (55924), Mishustin, SP, Centis, Rosella, Benedetti Andrea, Keshavjee, S, Kim, Hr, David Ashkin (139358), Chan Eward D., O'Riordan Philly, Li Jiehui, Hollm-Delgado, María G., Sotgiu, Giovanni, Lancaster, J, Hollm-Delgado Maria G., Eward D. Chan (139381), Van Der Walt, Martie L., D'Ambrosio Lia, Palmero Domingo, Vija Riekstina (139532), Iseman, MD, Vargas, M H, Jose Peña (5648725), Enarson, Donald, Nguyen Huy Dung, [No Value], Flanagan Katherine, Thelma E Tupasi, Strand, MJ, Eward D Chan, Jiehui Li (139490), Janice Westenhouse, Becerra, MC, Lia D'Ambrosio (139387), Maria G. Hollm-Delgado (139435), Westenhouse, J, Bauer, Melissa E B, Pirett Viiklepp (139581), Sotgiu Giovanni, Shim, Taesun, Leah G. Jarlsberg (139453), Shin, Sonya S., Kwonjune J. Seung (139542), Cox, H, Won-Jung Koh, Pirett Viiklepp, Chiang, Chen-Yuan, Sonya S. Shin (139554), Schaaf, H. Simon, Sifuentes-Osornio José, Flood, J, Royce Sarah, Ahuja, Shama Desai, Quelapio, Maria Imelda D, Migliori, Giovanni B., O'Riordan, Philly, Shiraishi Yuji, Katherine Flanagan (139400), Garcia-Garcia, ML, Andrea Benedetti (139371), Leimane, Vaira, Shama D. Ahuja (139357), Domingo Palmero (139512), Garcia-Garcia Maria L., Shin, SS, Masa Narita (139507), Melissa Bauer (139361), Park, S-k, Pérez Guzmán, C, Keshavjee Salmaan, Chiang, C-Y, Dung, Nh, Thelma E. Tupasi (139569), Joey Lancaster, Philly O'Riordan (139509), Melissa Bauer, Masa Narita, Collaborative Group for Meta-Analysis of Individual Patient Data in MDR-TB, Kwonjune J Seung, Holtz, TH, Sifuentes Osornio, J, Lancaster Joey, Shah Lena, Leah G Jarlsberg, Kim, H-R, Nguyen Huy Dung, Strand, Matthew J., Quelapio, Maria I. D., Werf, Tjip S. van der, Migliori Giovanni B., Nguyen, HD, Nguyen Huy Dung (139392), Lange, Christopher L., Royce, Sarah E., Granich, RM, D'Ambrosio, Lia, Koh, Wonjung, Yuji Shiraishi, O'Riordan, P, Yew, W W, Migliori, Giovanni Battista, Ponce-de-Leon, Alfredo, Avendano Monika, Schaaf H. Simon, Viiklepp, P, Iseman Michael D., Mishustin, S P, Narita Masa, Vaira Leimane, Jerome Robert (139535), Migliori, G B, Lancaster, Joey, Jarlsberg, L G, Van der Walt, M, Maria L. Garcia-Garcia (139412), Christophe Lange (139475), Reuben M. Granich (139426), Peña, J, Bauer, Melissa, Ahuja Shama D., Robert van Altena, Pasvol, Geoffrey, Lena Shah, Sarah Royce (122433), Gandhi Neel, Robert Jerome, Jarlsberg, LG, Giovanni B. Migliori (139497), Van der Werf TS,, Ashkin David, Van der Walt Martie, Flanagan, Katie L., Schaaf, Hendrik Simon, Quelapio, M I D, Won-Jung Koh (139466), Payam Tabarsi (95540), Westenhouse Janice, Vija Riekstina, Cox, Helen S., Dick Menzies (66118), Schaaf, H S, Leimane Vaira, Ponce-de-Leon Alfredo, Banerjee Rita, Lange, Christophe, Dennis Falzon (122428), Tupasi Thelma E., Quelapio, MID, Benedetti, Andrea, Giovanni Sotgiu (16787), Bayona Jamie N., Tabarsi, Payam, Narita, Masa, Garcia Garcia ML,, Helen Cox (66086), Ahuja, S D, DeRiemer, K, Yim, Jae-Joon, Peña, Jose, Chan, Eward D., Seung, KJ, Flanagan, Katherine, Mercedes C Becerra, Flood, Jennifer M., Sifuentes-Osornio, J, Mitnick, Carole Diane, Peña Sánchez de Rivera, José María, Wiel C. M. de Lange (139479), de Lange Wiel C. M., Alfredo Ponce-de-Leon, Yim, Jaejoon, Robert, Jerome, Mitnick, Carole, Shin Sonya S., Shiraishi, Yuji, Robert, Jérôme J., Leung, CC, Van der Walt, Martie, Sifuentes-Osornio, José, De Lange, Wiel C M, Philly O'Riordan, Seung, K J, Michael D Iseman, Tae Sun Shim (91684), Yew Wing Wai, Andrea Benedetti, Shin, S S, Ponce-de-León, Alfredo Alfredo, Michael D. Iseman (139449), David Ashkin, Carole D. Mitnick (94953), Seung Kwonjune J., Kim, Hyeryoun, Leung, C C, Seung-kyu Park (139515), Hollm-Delgado, Maria Graciela, Carole D Mitnick, Becerra Mercedes C., Holtz, Timothy H., H. Simon Schaaf (139539), Becerra, Mercedes C., Chiang Chen-Yuan, Hollm-Delgado, MG, Tabarsi, P, Donald Enarson (139395), Sergey P Mishustin, Rosella Centis, Peña Jose, Pérez-Guzmán Carlos, Tupasi, TE, Benedetti, A, Palmero, D, Tabarsi Payam, Mitnick, Carole D., Kim Hye-Ryoun, Falzon Dennis, Pai Madhukar, Jamie N Bayona, Geoffrey Pasvol (139518), Yew, Wing Wai, Shim, T S, H Simon Schaaf, DeRiemer, Kathryn, Vargas, Mario H., Dung, N H, Bayona, Jamie N., Koh, Wj, Pasvol, G, Rosella Centis (139378), Maria G Hollm-Delgado, Katherine Flanagan, DeRiemer, Kathy, Mercedes C. Becerra (139368), Jose Peña, Lange, C, Garcia-Garcia, Maria L., Mishustin, Sergey P., Janice Westenhouse (139584), Centis Rosella, Pérez-Guzmán, Carlos, Van der Werf, TS, Quelapio Maria I. D., José Sifuentes-Osornio (139563), Jarlsberg Leah G., Mitnick, C D, Park, Seungkyu, Chan, ED, Strand, M J, Hollm-Delgado, M G, Sonya S Shin, Pai, Madhukar, Holtz, T H, Shin, Sonya, Palmero, Domingo, Granich Reuben M., Shah, Lena, Palmero, Domingo Juan, Leimane, V, Burgos Marcos, Tjip S. Van der Werf (5648728), Riekstina, Vija, Gandhi, Neel, Madhukar Pai, Li, J, Domingo Palmero, Shama D Ahuja, Payam Tabarsi, Becerra, Mercedes, Sergey P. Mishustin (139502), Koh Won-Jung, Bayona, JN, Christophe Lange, Timothy H Holtz, Leung, Chichiu, Li, Jiehui, Vargas, MH, Wing Wai Yew, Mitnick, CD, Neel Gandhi, Mitnick Carole D., Benedetti, Andrea L., Burgos, Marcos, Carlos Pérez-Guzmán (139523), Becerra, M C, Sotgiu, G, Iseman, M D, van Altena, R, Monika Avendano, Granich, R M, Shim, Tae Sun, Leung Chi Chiu, Pasvol Geoffrey, Ponce de Leon, A, Lange Christophe, Seung-kyu Park, D'Ambrosio, L, Royce, Sarah, Maria L Garcia-Garcia, Menzies, D, Cox Helen, Park, Seung-kyu, Koh, Won-Jung, Maria I. D. Quelapio (139526), Kim, Hye-Ryoun, Mario H. Vargas (139578), Yuji Shiraishi (139560), Vaira Leimane (139482), Shim Tae Sun, Chan, Edward D., Chen-Yuan Chiang, Enarson, D, Geoffrey Pasvol, Avendano, Monika, Salmaan Keshavjee (139457), Pérez-Guzmán, C, Westenhouse, Janice L., Martie Van der Walt, Monika Avendano (139359), Cox, Helen, Wiel C M de Lange, Seung, Kwonjune J., Chi Chiu Leung (139485), de Lange, W C M, Van der Werf, T S, García García, María L., Rita Banerjee, Dung, Nguyen Huy, Jae-Joon Yim, Jennifer Flood (139406), Bauer Melissa, Flood Jennifer, Banerjee, R, Ahuja, SD, Kathy DeRiemer, Seung, Kwonjune, García-García, Lourdes, Hye-Ryoun Kim (139461), José Sifuentes-Osornio, Migliori, GB, Van der Werf, Tjip S., Mishustin Sergey P., Cox, Helen Suzanne, Avendano, M, Gandhi, Neel R., Lena Shah (139547), Granich, Reuben M., Dick Menzies, Strand Matthew J., Helen Cox, Tjip S Van der Werf, Chiang, Chenyuan, Royce, S, Marcos Burgos, Lange, Christoph, Alfredo Ponce-de-Leon (139529), Dung, Nguyenhuy, Yew, WW, Lange, Wiel C. M. de, Park Seung-kyu, Yim Jae-Joon, Narita, M, Reuben M Granich, Tupasi, T E, Vargas Mario H., Falzon, D, Hye-Ryoun Kim, Jennifer Flood, Shiraishi, Y, Jiehui Li, Centis, R, Enarson, Donald A., Giovanni B Migliori, Koh, W-J, Menzies, Dick, de Lange WC,, de lange, WCM, de Lange, Wiel C. M., Jerome Robert, Quelapio, Mi, Narita, Masahiro, Riekstina, V, DeRiemer Kathy, Keshavjee, Salmaan, O'Riordan, Philly, Chan, E D, Shah, L, Enarson Donald, Yim, Jj, Westenhouse, Janice, Carlos Pérez-Guzmán, Menzies Dick, Garcia-Garcia, M L, Bauer, M, Leung, Chi Chiu, van Altena Robert, Pai, M, Altena, Robert van, Donald Enarson, Park, Sk, Wing Wai Yew (139587), Salmaan Keshavjee, Robert, J, Chiang, Cy, Banerjee, Rita D., Giovanni Sotgiu, Ashkin, D, Kathy DeRiemer (139390), Holtz Timothy H., Schaaf, HS, Flood, Jennifer, Tupasi, Thelma E., Ashkin, David +450 morecore +2 more sourcesGut microbiota-driven immunomodulation in tuberculosis: targeting dysbiosis to overcome drug resistance
Frontiers in ImmunologyTuberculosis (TB) remains a major global health threat, hampered by the escalating prevalence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains.Qi Nie, Qi Nie, Xujuan Hu, Xujuan Hu, Yingjie Zhang, Yingjie Zhang, Ling Pan, Ling Pan, Xiaoqing Zhang, Xiaoqing Zhang, Yong Zhou, Yong Zhou, Tingting Fu, Tingting Fu, Lijuan Zheng, Lijuan Zheng, Fan Xiao, Fan Xiao, Yuan Liu, Yuan Liu, Si Du, Si Du, Jieguang Liu, Jieguang Liu, Leyiyi Liu, Leyiyi Liu, Xianglian Xiong, Xianglian Xiong, Yuanjun Wu, Yuanjun Wu, Dan Fan, Dan Fan, Lixuan Tao, Fuli Ren, Fuli Ren, Fuli Ren +35 moredoaj +1 more sourceHealth system factors influencing management of multidrug-resistant tuberculosis in four European Union countries - learning from country experiences
BMC Public Health, 2017 Background In the European Union and European Economic Area only 38% of multidrug-resistant tuberculosis patients notified in 2011 completed treatment successfully at 24 months’ evaluation.Gerard de Vries, Svetla Tsolova, Laura F. Anderson, Agnes C. Gebhard, Einar Heldal, Vahur Hollo, Laura Sánchez-Cambronero Cejudo, Daniela Schmid, Bert Schreuder, Tonka Varleva, Marieke J. van der Werf +10 moredoaj +1 more sourceMetal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis
BMEMat, EarlyView.LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang +4 morewiley +1 more sourceLinezolid-containing regimens for the treatment of drug-resistant tuberculosis in South African children.
, 2012 BACKGROUND: Treatment options for drug-resistant tuberculosis (DR-TB) are limited. Linezolid has been successfully used to treat DR-TB in adults, but there are few case reports of its use in children for TB.Rose, PC, Hallbauer, UM, Hesseling, AC, Schaaf, HS, Seddon, JA +4 morecore +1 more sourceNew drugs and vaccines for drug-resistant Mycobacterium tuberculosis infections [PDF]
, 2008 Tuberculosis remains the most common cause of death due to a single infective organism. Despite the availability of a vaccine and chemotherapeutic options, the global disease burden remains relatively unaffected.Willcox, Benjamin, Gurdyal S Besra, Bhatt, Apoorva; id_orcid, Dover, LG, Apoorva Bhatt, Dover, Lynn, Besra, Gurdyal; id_orcid, Besra, Gurdyal, Bhatt, Apoorva, Lynn G Dover, Bhowruth, Veemal, Veemal Bhowruth, Benjamin E Willcox +12 morecore +1 more sourceBridging the translational gap in clinical nanomedicine: From rational design to clinical reality
BMEMat, EarlyView.Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li +9 morewiley +1 more sourceEarly and efficient detection of Mycobacterium tuberculosis in sputum by microscopic observation of broth cultures. [PDF]
, 2013 Early, efficient and inexpensive methods for the detection of pulmonary tuberculosis are urgently needed for effective patient management as well as to interrupt transmission. These methods to detect M. tuberculosis in a timely and affordable way are not Benson R Kidenya, Fitzgerald, Daniel W., Kidenya, Benson R, Serena P Koenig, Kabangila Rodrick, Peck Robert N., Mshana, Stephen E., Mshana Stephen E., Rodrick Kabangila, Warren D Johnson, Peck, Robert N., Koenig Serena P., Fitzgerald, Daniel W, Kidenya Benson R., Webster, Lauren E., Lauren E Webster, Webster Lauren E., Daniel W Fitzgerald, Kidenya, Benson R., Koenig, Serena P, Mshana, Stephen E, Robert N Peck, Webster, Lauren E, Stephen E Mshana, Peck, Robert N, Johnson, Warren D, Fitzgerald Daniel W., Kabangila, Rodrick, Johnson, Warren D., Koenig, Serena, Johnson Warren D. +30 morecore +2 more sources