Results 71 to 80 of about 1,086,070 (250)

Primary Antimicrobial Resistance Among Mycobacterium Tuberculosis Isolates from HIV Seropositive and HIV Seronegative Patients in Dar es Salaam Tanzania. [PDF]

, 2008
The United Republic of Tanzania is one of the 22 high M. tuberculosis burden countries. Data collected between 2002 and 2007 indicate that the global prevalence of drug-resistant M. tuberculosis including MDR vary greatly.
Saathoff, Elmar, Mugusi, F., Saathoff, E., Moshiro Candida, Bosch, R., Urassa, W., Urassa, Willy, Mugusi Ferdinand, Fawzi Wafaie, Villamor, E., Mugusi, Ferdinand, Moshiro, C., Fawzi, W., Bosch, Ronald, Saathoff Elmar, Bosch Ronald, Msamanga Gernard, Msamanga, Gernard, Moshiro, Candida, Villamor Eduardo, Villamor, Eduardo, Fawzi, Wafaie, Urassa Willy   +22 more
core   +1 more source

Treatment of multidrug-resistant tuberculosis in a remote, conflict-affected area of the Democratic Republic of Congo. [PDF]

, 2012
The Democratic Republic of Congo is a high-burden country for multidrug-resistant tuberculosis. Médecins Sans Frontières has supported the Ministry of Health in the conflict-affected region of Shabunda since 1997.
Shah, T, Maneno, M, Masumbuko, E W, Ngoy, N M, Shanks, L, Bartlett, S, Thi, S S   +6 more
core   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

Factors associated with isoniazid resistant tuberculosis among human immunodeficiency virus positive patients in Swaziland: a case-control study

BMC Infectious Diseases, 2019
Background Isoniazid resistant tuberculosis is the most prevalent type of resistance in Swaziland and over two-thirds of the isoniazid resistant tuberculosis patients are tuberculosis and human immunodeficiency virus co-infected.
Nonhlanhla Christinah Dlamini, Dar-Der Ji, Li-Yin Chien   +2 more
doaj   +1 more source

Factors affecting outcome of longer regimen multidrug-resistant tuberculosis treatment in West Java Indonesia: A retrospective cohort study.

PLoS ONE, 2021
BackgroundMultidrug-resistant tuberculosis had high treatment failure and mortality. Success rate of treatment currently 56% at global level, 48% in Indonesia and 36% in West Java province, the most populated province and surround Jakarta, the capitol of
Arto Yuwono Soeroto, Chica Pratiwi, Prayudi Santoso, Bony Wiem Lestari   +3 more
doaj   +1 more source

Transmission of multidrug-resistant tuberculosis

The Pediatric Infectious Disease Journal, 2000
To compare the Mycobacterium tuberculosis isolates of adult index cases with multidrug-resistant (MDR) tuberculosis to the isolates obtained from their child contacts.A 4-year prospective study in the Western Cape Province of South Africa. We evaluated 149 child contacts of 80 adult MDR pulmonary tuberculosis cases.
Schaaf H.S., Van Rie A., Gie R.P., Beyers N., Victor T.C., Van Helden P.D., Donald P.R.   +6 more
openaire   +4 more sources

Boronic Acid Inhibitors of β‐Lactamases: A Promising Strategy Against Antimicrobial Resistance

Medicinal Research Reviews, EarlyView.
ABSTRACT The rise of antimicrobial resistance (AMR) poses a critical threat to global health, mostly due to the proliferation of β‐lactamases, a class of enzymes responsible for the inactivation of β‐lactam antibiotics. Among the most promising strategies to restore β‐lactam efficacy is the use of β‐lactamase inhibitors (BLIs), with boronic acid ...
Nicolò Santi, Federico Corsini, Robert A. Bonomo, Emilia Caselli, Fabio Prati   +4 more
wiley   +1 more source

Sequence analyses of just four genes to detect extensively drug-resistant Mycobacterium tuberculosis strains in multidrug-resistant tuberculosis patients undergoing treatment [PDF]

, 2009
The rapid detection of Mycobacterium tuberculosis isolates resistant to second-line drugs is crucial for the institution of appropriate treatment regimens as early as possible.
Braker, K, Zarkua, N, Niemann, S, Feuerriegel, S, Cox, H S, Rüsch-Gerdes, S, Karimovich, H A   +6 more
core   +1 more source

Treatment outcomes for children with multidrug-resistant tuberculosis: a systematic review and meta-analysis [PDF]

, 2012
BACKGROUND: Paediatric multidrug-resistant (MDR) tuberculosis is a public health challenge of growing concern, accounting for an estimated 15% of all global cases of MDR tuberculosis. Clinical management is especially challenging, and recommendations are
Ettehad, Dena, Schaaf H.S., Schaaf, H S, Ettehad, D, Ford, N, Ford, Nathan, Seddon, J A, Cooke, Graham S, Ettehad D., Ford N., Schaaf, H Simon, Seddon, James A, Cooke G.S., Cooke, G S, Seddon J.A.   +14 more
core   +1 more source

Multidrug-resistant and heteroresistant Mycobacterium tuberculosis and associated gene mutations in Ethiopia

International Journal of Infectious Diseases, 2015
Background: The prevalence of multidrug-resistant tuberculosis (TB) among new and retreatment cases in 2011 in Ethiopia was 2.7% and 17.9%, respectively.
Daniel Mekonnen, Aschalew Admassu, Wondemagegn Mulu, Aranzazu Amor, Agustín Benito, Woynshet Gelaye, Fantahun Biadglegne, Bayeh Abera   +7 more
doaj   +1 more source