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Multidrug-Resistant Tuberculosis
New England Journal of Medicine, 1992Excerpt As recently as 10 years ago, tuberculosis was rapidly disappearing from the United States.
Kenrad E. Nelson +5 more
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Multidrug-resistant tuberculosis
Infectious Disease Clinics of North America, 2002Multidrug-resistant TB is a growing public health problem. Although control of the multidrug-resistant TB epidemic has been achieved in New York City, strains of multidrug-resistant TB are found in nearly every state. Much of the world faces a growing problem with no immediate solution.
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Multidrug resistance in Mycobacterium tuberculosis
International Journal of Antimicrobial Agents, 1997All but one of the four major mechanisms of resistance to antimicrobial agents-inactivation of the drug, altered cell wall permeability or drug efflux, drug titration due to target overproduction, and alteration of the target by mutation-appear to be employed by Mycobacterium tuberculosis in its resistance to components of short course chemotherapy ...
Heym, B, Cole, S T
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Linezolid for multidrug-resistant tuberculosis
The Lancet Infectious Diseases, 2013In their Comment in The Lancet Infectious Diseases, Kwok-Chiu Chang and colleagues concluded that expansion of access to linezolid for complicated cases of drug-resistant tuberculosis risks the loss of a potentially useful drug and could promote the emergence and spread of drug-resistant tuberculosis in the community.
Nathan Ford +4 more
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Treatment of Multidrug-Resistant Tuberculosis
New England Journal of Medicine, 1993The frequency of infections with M. tuberculosis resistant to antituberculous drugs is increasing in the United States and globally. This increase is a major threat to tuberculosis treatment and control programs. To prevent this situation from worsening, initial treatment programs that entail directly observed therapy supported by effective inducements
Alastair J.J. Wood, Michael D. Iseman
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Multidrug resistant cervical tuberculosis
American Journal of Otolaryngology, 1999Tuberculosis (TB) remains a global health problem, with an annual incidence of 8 to 10 million cases and the death of 3 million people year1y.l Despite the continuous decline of TB in the United States since the 185Os, an increase in new TB cases was observed in 1985.
Aijaz Alvi +3 more
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Confronting Multidrug-Resistant Tuberculosis
New England Journal of Medicine, 2012Microbial resistance to antituberculosis drugs has existed since the dawn of the antibiotic era.1 Multidrug-resistant (MDR) tuberculosis, defined by resistance to isoniazid and rifampin, requires treatment for up to 2 years with expensive second-line drugs that have poor side-effect profiles; success rates rarely exceed 65 to 75%.
Eric L. Nuermberger, Richard E. Chaisson
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Multidrug resistant tuberculosis
Pathology, 2011Multidrug resistant tuberculosis (MDRTB) and extensively resistant TB (XDRTB) are an increasing problem worldwide, especially in resource-poor nations. MDRTB is associated with vastly increased therapeutic costs and increased treatment failure rates.
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Multidrug-Resistant Tuberculosis Spondylitis
Acta Clinica Belgica, 2000We report a case of multidrug-resistant spinal tuberculosis complicated by epiduritis and paraspinal abscess in a 68-year-old black woman. Multidrug-resistant tuberculous spondylitis is still rare in Belgium. Two others cases were reported from 1992 to 1997.
Cherifi, Soraya +2 more
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Enfermedades Infecciosas y Microbiología Clínica, 2008
The emergence and spread of Mycobacterium tuberculosis strains resistant to multiple drugs represent a threat for global tuberculosis control. The World Health Organization (WHO) estimates that almost 500,000 cases of M. tuberculosis resistant to isoniazid and rifampicin (multidrug-resistant, or MDR-TB), at least, emerged in 2006.
Fernando Alcaide, Miguel Santin
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The emergence and spread of Mycobacterium tuberculosis strains resistant to multiple drugs represent a threat for global tuberculosis control. The World Health Organization (WHO) estimates that almost 500,000 cases of M. tuberculosis resistant to isoniazid and rifampicin (multidrug-resistant, or MDR-TB), at least, emerged in 2006.
Fernando Alcaide, Miguel Santin
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