Results 101 to 110 of about 1,747,294 (351)

A cooperative release of mitochondrial DNA from platelets and neutrophils drives an interferon signature in systemic sclerosis

Arthritis &Rheumatology, Accepted Article.
Objective Mitochondria are organelles with a hypomethylated circular genome. Mitochondrial DNA (mtDNA) in the systemic circulation has been implicated in inflammation. This study investigates the role of circulating DNA in systemic sclerosis (SSc) and the cellular mechanisms governing its release.
Stavros Giaglis, André N. Tiaden, Simone Häner‐Massimi, Diego Kyburz, Cedric André, Anton Glück, Enrico Ferrero, Stuart Hawtin, Tobias Junt, Ulrich A. Walker   +9 more
wiley   +1 more source

Pharmacokinetic Bioequivalence and Safety Assessment of Two Venlafaxine Hydrochloride Extended-Release Capsules in Healthy Chinese Subjects Under Fed Conditions: A Randomized, Open-Label, Single-Dose, Crossover Study

Drugs in R&D
Background and Objective Venlafaxine hydrochloride extended-release (ER) capsules are commonly used to treat depression and anxiety disorders. Evaluation of the bioequivalence of generic formulations with reference products is essential to ensure ...
Yingxia He, Jie Wang, Fang Yao, Pan Lu, Yafang Xie, Xiuwen Li, Qiangwei Liu, Yang Liu, Dan Cao, Jun Liang, Dan Tian, Guan Liu   +11 more
doaj   +1 more source

Critical role of molecular test in early diagnosis of gastric tuberculosis: a rare case report and review of literature

BMC Infectious Diseases, 2019
Backgroud Early diagnosis of gastric tuberculosis is often challenging because the disease is very rare and its clinical manifestation is nonspecific and misleading. To raise the awareness and emphasize early diagnosis of gastric tuberculosis, we present
Jun Ma, Hongyun Yin, Huikang Xie
doaj   +1 more source

Bronchoscopic evaluation and final diagnosis in patients with chronic non productive cough with normal Chest X ray [PDF]

, 2010
When a proper detailed history, clinical examination, chest X ray and sputum analysis does not yield a definite diagnosis for the cause of chronic cough, bronchoscopy is indicated.
Anupama, N, Mithra, PP, Pradeep, NP, Vishnu, SM   +3 more
core   +1 more source

Comparative Study of GeneXpert with ZN Stain and Culture in Samples of Suspected Pulmonary Tuberculosis.

Journal of clinical and diagnostic research : JCDR, 2016
INTRODUCTION Tuberculosis remains one of the deadliest communicable diseases. There are number of tests available for the diagnosis of tuberculosis but conventional microscopy has low sensitivity and culture although gold standard, but takes longer time ...
M. Agrawal, A. Bajaj, Vinaya Bhatia, S. Dutt   +3 more
semanticscholar   +1 more source

Population pharmacokinetics of levofloxacin in breastmilk in patients with rifampicin‐resistant tuberculosis

British Journal of Clinical Pharmacology, EarlyView.
Levofloxacin is a widely used antibiotic included in rifampicin‐resistant tuberculosis (RR‐TB) treatment. Data describing levofloxacin concentrations in breastmilk and infant exposure are limited. We analysed data from two South African studies of breastfeeding women receiving levofloxacin (750–1000 mg daily) for RR‐TB.
Sharon Sawe, Lufina Tsirizani, Buyisile Mkhize, Lubbe Wiesner, Gary Maartens, Francesca Conradie, Richard Court, Marian Loveday, Catriona Waitt, Paolo Denti   +9 more
wiley   +1 more source

Tuberculosis treatment in a refugee and migrant population: 20 years of experience on the Thai-Burmese border. [PDF]

, 2010
Although tuberculosis (TB) is a curable disease, it remains a major global health problem and an important cause of morbidity and mortality among vulnerable populations, including refugees and ...
Bonnet, M, Camelique, O, Guerin, P J, Hewison, C, Hsa Thaw, K, Minetti, A, Pinoges, L, Swaddiwudhipong, W, Thi, S   +8 more
core   +1 more source

Tuberculosis in Dr Granville's mummy: a molecular re-examination of the earliest known Egyptian mummy to be scientifically examined and given a medical diagnosis [PDF]

, 2010
‘Dr Granville's mummy’ was described to the Royal Society of London in 1825 and was the first ancient Egyptian mummy to be subjected to a scientific autopsy.
Abu Al-Soud W., Boom R., David E. Minnikin, Forbes B. A., Granville A. B., Gurdyal S. Besra, Harer W. B., Helen D. Donoghue, Hellyer T. J., John H. Taylor, Mark Spigelman, Minnikin D. E., Oona Y.-C. Lee, Tapp E., Taylor G. M., Taylor G. M.   +15 more
core   +2 more sources

Xpert® Mtb/Rif assay for pulmonary tuberculosis and rifampicin resistance in adults

Cochrane Database of Systematic Reviews, 2013
Background Accurate and rapid detection of tuberculosis (TB) and drug resistance are critical for improving patient care and decreasing the spread of TB.
K. Steingart, Hojoon Sohn, Ian Schiller, Lorie A. Kloda, C. Boehme, M. Pai, N. Dendukuri   +6 more
semanticscholar   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source