Results 121 to 130 of about 975,760 (305)

Real World Use of the IL‐36 Receptor Antagonist Spesolimab: A Systematic Review and Analysis

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Spesolimab, an interleukin‐36 receptor antagonist, is approved for the treatment and prevention of generalised pustular psoriasis (GPP) flares. Its use has increasingly been reported in real‐world settings for both GPP and other inflammatory dermatoses.
Sophia A. Mense, Nicole Bavaro, Aashna Farishta, Jiaqi Chen, Raj Chovatiya   +4 more
wiley   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Disease Burden, Temporal Trends, and Key Influencing Factors of Lower Respiratory Infections in Asia, 1990–2023: Based on GBD 2023

Med Research, EarlyView.
In 2023, marked regional heterogeneity was observed across Asia: South Asia carried the highest incidence and prevalence, Central Asia had the highest DALY rate, Southeast Asia bore the highest mortality and East Asia and High‐income Asia‐Pacific generally had lower rates.
Lingxia Zhang, Yufeng Li, Enjun Dong, Mingming Zhang, Yuan Tian, Shuang Zhou, Ruizi Ni, Yajing An, Xiaojuan Qin, Bingrui Gao, Qi Shen, Weiguo Sun, Yanhua Liu, Wenping Gong   +13 more
wiley   +1 more source

Developing a framework for identifying risk factors and estimating direct economic disease burden attributable to healthcare-associated infections: a case study of a Chinese Tuberculosis hospital

Global Health Research and Policy
Healthcare-associated infections (HAIs) represent a major global health burden, which necessitate effective frameworks to identify potential risk factors and estimate the corresponding direct economic disease burden.
Nili Ren, Xinliang Liu, Yi Luo, Guofei Li, Ying Huang, Desheng Ji, Cheng Peng, Jing Sun, Hao Li   +8 more
doaj   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

Boronic Acid Inhibitors of β‐Lactamases: A Promising Strategy Against Antimicrobial Resistance

Medicinal Research Reviews, EarlyView.
ABSTRACT The rise of antimicrobial resistance (AMR) poses a critical threat to global health, mostly due to the proliferation of β‐lactamases, a class of enzymes responsible for the inactivation of β‐lactam antibiotics. Among the most promising strategies to restore β‐lactam efficacy is the use of β‐lactamase inhibitors (BLIs), with boronic acid ...
Nicolò Santi, Federico Corsini, Robert A. Bonomo, Emilia Caselli, Fabio Prati   +4 more
wiley   +1 more source

Factors Associated with Delay in Diagnosis of Tuberculosis in Ardabil Province [PDF]

Background and objectives: Transmission of tuberculosis occurs usually by aerosols, Produced with patient’s cough. So early diagnosis and proper treatment of patients as a disease reservoir, has a special importance.
معینی جزنی, آرزو, مؤیدنیا, ناصر, قبادی مراللو, حسن, پورفرضی, فرهاد, کمال نیا, فرنگیس, پورمحمد جان, ناهید, مهرپور, روشنک, علاف اصغری, امین, غریبانی, مجید محمد, جمالی, اسماعیل, صادقی, اکرم, خلیق, نغمه, آقابالايی, محرم, اناری, حسن, حضرتی, صادق, صالح زاده, فرهاد, بهبودی, صائمه, براک, منوچهر, قاسمی, احمد, رفیعی, مهدی, حبیب زاده, شهرام, میرزا آقازاده, محمد, خانجانیان, گیتا   +22 more
core  

Artificial Intelligence‐Driven Natural Product Drug Discovery: From Computational Genome Mining to Clinical Translation

Medicinal Research Reviews, EarlyView.
ABSTRACT Natural products (NPs) have historically yielded numerous therapeutic agents, yet their integration into modern drug discovery has been constrained by chemical complexity, low abundance, laborious dereplication, and limited target annotation.
Antonio Lavecchia
wiley   +1 more source

Trends and risk factors of care-seeking delay among students with pulmonary tuberculosis in Wuhan, China, 2012–2025

Frontiers in Public Health
BackgroundCare-seeking delay among students with tuberculosis (TB) poses a significant barrier to school-based TB prevention and control. Such delay facilitates the transmission of Mycobacterium tuberculosis in high-density populations and frequently ...
Zhengbin Zhang, Wei Zhang, Gang Wu, Jianjie Wang, Aiping Yu, Jun Chen, Zhouqin Lu, Guiyang Wang, Tiantian Wang, Xiaojun Wang, Jing Hu, Yuehua Li   +11 more
doaj   +1 more source

Membranous Nephropathy and Pulmonary Tuberculosis: An Uncommon Combination: Case Report [PDF]

It is imperative to evaluate for secondary causes of membranous glomerulonephritis, from infections such as hepatitis B and C, viruses and parasites, autoimmune diseases like systemic lupus erythematosus, and other neoplasms. Tuberculosis associated with
Sanggita Checker, Puneet Bhuwania, Aniket Mule   +2 more
core   +1 more source