Results 111 to 120 of about 917,791 (305)

Enhanced strategies for cuproptosis‐like death in bacterial infection treatment

BMEMat, EarlyView.
This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang, Bolong Xu, Ruiyuan Zhu, Hengshuo Gui, Tian Xia, Shaokai Liu, Huiyu Liu, Xianwen Wang   +7 more
wiley   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

BMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang   +4 more
wiley   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Optimal tuberculosis case-finding methodologies for field trials of new tuberculosis vaccines in young children [PDF]

, 2013
Includes bibliographical references.There is paucity of evidence to guide case-finding strategies in field trials of new tuberculosis vaccines conducted in young children.
Moyo, Sizulu
core   +1 more source

Differential mast cell numbers and characteristics in human tuberculosis pulmonary lesions. [PDF]

Sci Rep, 2021
Garcia-Rodriguez KM, Bini EI, Gamboa-Domínguez A, Espitia-Pinzón CI, Huerta-Yepez S, Bulfone-Paus S, Hernández-Pando R.   +6 more
europepmc   +1 more source

Ethnic variation in inflammatory profile in tuberculosis [PDF]

, 2013
Distinct phylogenetic lineages of Mycobacterium tuberculosis (MTB) cause disease in patients of particular genetic ancestry, and elicit different patterns of cytokine and chemokine secretion when cultured with human macrophages in vitro.
Bothamley, GH, Baker Lucy V., Nikolayevskyy, V, Barker, Richard D., Adrian R. Martineau (136644), Heather J Milburn, Drobniewski, Francis A., Nuamah, RA, Martineau, AR, Timms Peter M., Francis A. Drobniewski (349928), Coussens, Anna K., Griffiths, CJ, Vladyslav Nikolayevskyy, Drobniewski, FA, Bhaw-Rosun, L, Rosamond A. Nuamah (430904), Kamrul Islam (430894), Coussens Anna K., Francis A Drobniewski, Milburn, HJ, Davidson Robert N., Nuamah Rosamond A., Alleyna P Claxton, Charles A Mein, Yasmeen Hanifa, Yasmeen Hanifa (430893), Drobniewski Francis A., Elkington, Paul T., Graham H. Bothamley (430896), Claxton Alleyna P., Graham H Bothamley, Elkington Paul T., Peter M. Timms (430895), Anna K. Coussens (430892), Davidson, Robert N., Vladyslav Nikolayevskyy (349919), Bhaw-Rosun Leena, Milburn, Heather, Martineau, Adrian R., Paul T. Elkington (364501), Packe, Geoffrey E., Mein, Charles A., Young, Douglas B., Geoffrey E Packe, Martineau Adrian R., Islam, Kamrul, Packe, GE, Mathina Darmalingam, Anna K Coussens, Robert N Davidson, Mathina Darmalingam (430899), Timms, Peter M., Rosamond A Nuamah, Hanifa, Yasmeen, Elkington, PT, Lucy V. Baker (430901), Nikolayevskyy, Vladyslav, Bothamley, Graham H., Richard D. Barker (430902), Milburn, Heather J., Leena Bhaw-Rosun (430903), Robert J Wilkinson, Baker, Lucy V., Darmalingam, M, Wilkinson, Robert J., Christopher J Griffiths, Bothamley Graham H., Robert J. Wilkinson (130050), Hanifa Yasmeen, Claxton, Alleyna P., Kamrul Islam, Darmalingam Mathina, Barker, RD, Peter M Timms, Wilkinson Robert J., Griffiths Christopher J., Islam Kamrul, Nuamah, Rosamond A., Hanifa, Y, Packe Geoffrey E., Barker Richard D., Claxton, AP, Alleyna P. Claxton (430897), Robert N. Davidson (364270), Coussens, AK, Timms, PM, Paul T Elkington, Christopher J. Griffiths (430905), Leena Bhaw-Rosun, Davidson, RN, Milburn Heather J., Griffiths, Christopher J., Lucy V Baker, Geoffrey E. Packe (430898), Richard D Barker, Darmalingam, Mathina, Nikolayevskyy Vladyslav, Heather J. Milburn (430900), Mein, CA, Charles A. Mein (46734), Baker, LV, Wilkinson, RJ, Adrian R Martineau, Mein Charles A., Bhaw-Rosun, Leena, Islam, K   +106 more
core   +1 more source

Long‐Acting Therapeutics in Pediatric Health: Bridging Innovation and Access

Clinical Pharmacology &Therapeutics, EarlyView.
Children have distinct therapeutic needs arising from age‐dependent physiology, disease epidemiology, formulation requirements, dosing considerations, and safety vulnerabilities. Despite substantial reductions in childhood mortality over the past three decades, nearly 5 million children under five died in 2023, with infectious diseases continuing to ...
Prajith Venkatasubramanian, Moherndran Archary, Daniel B. Hawcutt, Rachel Daley, Edmund Capparelli, Adeniyi Olagunju   +5 more
wiley   +1 more source

Genetic association and expression studies indicate a role of toll-like receptor 8 in pulmonary tuberculosis. [PDF]

, 2008
Despite high rates of exposure, only 5-10% of people infected with Mycobacterium tuberculosis will develop active tuberculosis (TB) disease, suggesting a significant role for genetic variation in the human immune response to this infection.
Crevel, R. van, Carine Bonnard, Hazel E E Wong, Sahiratmadja Edhyana, Wong, Hazel EE, Ottenhoff, THM, Nejentsev, S., van de Vosse, Esther, Bonnard, C, Ottenhoff, T.H., Martin L Hibberd, Jeffrey S Szeszko, Ottenhoff Tom H. M., Reinout van Crevel, Balabanova, Yanina, van Crevel Reinout, Nejentsev Sergey, Seielstad, M., Ottenhoff, Tom HM, Tom H M Ottenhoff, van Crevel, Reinout, Sahiratmadja, Edhyana, Wong, H.E., Yanina Balabanova, Szeszko Jeffrey S., Hari Dass, Ranjeeta, Alisjahbana Bachti, Szeszko, Jeffrey S, Edhyana Sahiratmadja, Bonnard, Carine, Bachti Alisjahbana, Szeszko, J.S., Francis Drobniewski, Davila, Sonia, Alisjahbana, B., Hibberd, M.L., Hari Dass, R., Balabanova, Y., Alisjahbana, Bachti, van de Vosse, E, Alisjahbana, B, Bonnard Carine, Hari Dass Ranjeeta, Sonia Davila, Ranjeeta Hari Dass, Nejentsev, S, Szeszko, JS, Nejentsev, Sergey, Davila, S, Sergey Nejentsev, Seielstad Mark, Dass, Ranjeeta Hari, van Crevel, R, Bonnard, C., Dass, RH, Hibberd Martin L., Balabanova Yanina, van de Vosse Esther, Vosse, E. van de, Mark Seielstad, Seielstad, M, Hibberd, ML, Balabanova, Y, Davila, S., Drobniewski, F, Sahiratmadja, E., Davila Sonia, Drobniewski, Francis, Seielstad, Mark, Drobniewski, F., Wong, HEE, Hibberd, Martin L, Sahiratmadja, E, Esther van de Vosse, Wong Hazel E. E., Drobniewski Francis   +75 more
core   +3 more sources

A case report: Diagnosis and treatment of idiopathic hypertrophic pachymeningitis

Ibrain, Volume 11, Issue 1, Page 112-116, Spring 2025.
We reported a case of idiopathic hypertrophic dura meningitis diagnosed in our hospital. The patient repeatedly suffered from headaches, followed by blurred vision in the right eye. During this period, multiple sclerosis was considered for diagnosis, and it improved after hormone treatment.
Zhong Luo, Piao Cao, Jing‐Qing Xu, Rong Yan, Jian Wang, Tao Liang, Ya Chen, Zu‐Cai Xu   +7 more
wiley   +1 more source

Nanopore-targeted sequencing: A new and effective technique for the diagnosis of non-tuberculous mycobacteria pulmonary disease

International Journal of Medical Microbiology
Non-tuberculous mycobacteria pulmonary disease (NTM-PD) has become a significant public health issue threatening human health in recent years. Traditional mycobacterial culture is complex, time-consuming, and unable to identify NTM at the species level ...
Li-ping Cheng, Li Wang, Yun-fei Wang, Jin-hui Yang, Jie Cao, Xiao-na Shen, Zhi-bin Liu, Wei Wei, Wei Sha, Qin Sun   +9 more
doaj   +1 more source