Results 101 to 110 of about 917,791 (305)

Integrated Clinical and Proteomic Profiling of CD19 Chimeric Antigen Receptor T Cell Therapy in Progressive Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective To characterize the clinical, immunologic, and proteomic changes associated with CD19 chimeric antigen receptor T cell therapy in patients with progressive systemic sclerosis (SSc). Methods Patients with progressive SSc received CD19 chimeric antigen receptor (CAR)‐T cell therapy and were observed longitudinally for safety, clinical efficacy,
Chenhan Jia, Wanyi Lin, Zhangyi Zhao, Fenglin Wu, Chaoyu Gu, Yuankai Sun, Zhe Ding, Chang Wei, Xinyu Li, Cuiwei Xie, Peng Xia, Zhen Xia, Xuesong Liu, Shaoying Yang, Chunyan Zhang, Hanlin Yin, Liangjing Lu   +16 more
wiley   +1 more source

Characteristics of peripheral Vγ2Vδ2 T cells in interferon-γ release assay negative pulmonary tuberculosis patients

BMC Infectious Diseases, 2018
Background It is not fully explained why some active tuberculosis patients show negative interferon-γ release assays (IGRAs). In this study, we tried to explore associations of IGRAs with the characteristics of peripheral Vγ2Vδ2 T cells and their ...
Liping Yan, Hongbo Shen, Heping Xiao
doaj   +1 more source

Deucravacitinib in Active Psoriatic Arthritis: Efficacy and Safety up to 52 Weeks From the Randomized, Double‐Blind, Phase 3 POETYK PsA‐2 Trial

Arthritis &Rheumatology, Accepted Article.
Objective To assess the efficacy and safety of deucravacitinib, an oral, selective tyrosine kinase 2 inhibitor, in patients with psoriatic arthritis (PsA) who were naive to biologic disease‐modifying antirheumatic drugs or received tumor necrosis factor inhibitors. Methods In the 52‐week (W), double‐blind, placebo‐controlled, phase 3 POETYK PsA‐2 study
Philip J. Mease, Vinod Chandran, April W. Armstrong, Ricardo Blanco, Alexis Ogdie, Evan L. Siegel, Alice B. Gottlieb, Xiaofeng Zeng, Diamant Thaçi, Mitsumasa Kishimoto, Hendrik Schulze‐Koops, Alan Kivitz, Eva Dokoupilová, Akimichi Morita, Eric M. Ruderman, Michael Plewinski, Kejia Wang, Caroline Sardinas, Eleni Vritzali, John Vaile, Atul Deodhar   +20 more
wiley   +1 more source

Pleural Metastatic Melanoma with Refractory Hemorrhagic Effusion: A Case Report

Cancer Management and Research
Yuxiang Xu,1,* Kaixue Zhuang,1,* Weijian Liu,1 Peize Zhang,1 Hongjuan Qin,1 Taosheng Ye1,21Department of Pulmonary Medicine and Tuberculosis, The Third People’s Hospital of Shenzhen, Southern University of Science and Technology, Shenzhen,
Xu Y, Zhuang K, Liu W, Zhang P, Qin H, Ye T   +5 more
doaj  

Pharmacokinetic Bioequivalence and Safety Assessment of Two Venlafaxine Hydrochloride Extended-Release Capsules in Healthy Chinese Subjects Under Fed Conditions: A Randomized, Open-Label, Single-Dose, Crossover Study

Drugs in R&D
Background and Objective Venlafaxine hydrochloride extended-release (ER) capsules are commonly used to treat depression and anxiety disorders. Evaluation of the bioequivalence of generic formulations with reference products is essential to ensure ...
Yingxia He, Jie Wang, Fang Yao, Pan Lu, Yafang Xie, Xiuwen Li, Qiangwei Liu, Yang Liu, Dan Cao, Jun Liang, Dan Tian, Guan Liu   +11 more
doaj   +1 more source

Associated factors for treatment delay in pulmonary tuberculosis in HIV-infected individuals: a nested case-control study. [PDF]

, 2012
BACKGROUND: The delay in initiating treatment for tuberculosis (TB) in HIV-infected individuals may lead to the development of a more severe form of the disease, with higher rates of morbidity, mortality and transmissibility. The aim of the present study
Laura Cunha Rodrigues, Líbia Vilela Moura, Miranda-Filho, Demócrito de Barros, Maruza Magda, Ricardo Arraes de Alencar Ximenes, Rodrigues Laura, Ximenes Ricardo Arraes de Alencar, Moura Líbia, Heloísa Ramos Lacerda, Lacerda, Heloísa Ramos, George Tadeu Nunes Diniz, Diniz George Tadeu, Miranda-Filho Demócrito de, Lacerda Heloísa, Maria de Fátima Pessoa Militão-Albuquerque, Magda Maruza, Moura, Líbia Vilela, Isabella Coimbra, Coimbra, Isabella, Coimbra Isabella, Militão-Albuquerque, Maria de Fátima Pessoa, Diniz, George Tadeu Nunes, Demócrito de Barros Miranda-Filho, Maruza, Magda, Militão-Albuquerque Maria de Fátima Pessoa, Rodrigues, Laura Cunha, Ximenes, Ricardo Arraes de Alencar   +26 more
core   +2 more sources

Population pharmacokinetics of levofloxacin in breastmilk in patients with rifampicin‐resistant tuberculosis

British Journal of Clinical Pharmacology, EarlyView.
Levofloxacin is a widely used antibiotic included in rifampicin‐resistant tuberculosis (RR‐TB) treatment. Data describing levofloxacin concentrations in breastmilk and infant exposure are limited. We analysed data from two South African studies of breastfeeding women receiving levofloxacin (750–1000 mg daily) for RR‐TB.
Sharon Sawe, Lufina Tsirizani, Buyisile Mkhize, Lubbe Wiesner, Gary Maartens, Francesca Conradie, Richard Court, Marian Loveday, Catriona Waitt, Paolo Denti   +9 more
wiley   +1 more source

Critical role of molecular test in early diagnosis of gastric tuberculosis: a rare case report and review of literature

BMC Infectious Diseases, 2019
Backgroud Early diagnosis of gastric tuberculosis is often challenging because the disease is very rare and its clinical manifestation is nonspecific and misleading. To raise the awareness and emphasize early diagnosis of gastric tuberculosis, we present
Jun Ma, Hongyun Yin, Huikang Xie
doaj   +1 more source

Pulmonary Tuberculosis [PDF]

Pulmonary Medicine, 2013
Anete Trajman, José R. Lapa e Silva, Margareth Dalcolmo, Jonathan E. Golub   +3 more
openaire   +3 more sources

Plasma drug activity assay for treatment optimization in tuberculosis patients [PDF]

, 2011
Item does not contain fulltextLow antituberculosis (TB) drug levels are common, but their clinical significance remains unclear, and methods of measurement are resource intensive.
Scott K. Heysell, Mpagama, S., Kibiki, Gibson S, Houpt, Eric R, Mwaigwisya, S., Heysell, Scott K, Ndusilo, Norah, Pholwat, Suporn, Mwaigwisya, Solomon, Kibiki, G.S., Solomon Mwaigwisya, Suporn Pholwat, Jean Gratz, Mtabho, C., Aarnoutse, R.E., Stellah Mpagama, Heysell, S.K., Rob E. Aarnoutse, Charles Mtabho, Gratz, J., Mpagama, Stellah, Norah Ndusilo, Gratz, Jean, Houpt, E.R., Gibson S. Kibiki, Eric R. Houpt, Mtabho, Charles, Aarnoutse, Rob E, Ndusilo, N., Pholwat, S.   +29 more
core   +1 more source