Results 181 to 190 of about 273,523 (312)

Recent progress on nanotechnologies for enhancing blood‐brain barrier permeability

Smart Molecules, EarlyView.
In this review, we summarize innovative strategies for harnessing the power of nanotechnology to enhance blood‐brain barrier permeability, a key challenge for central nervous system (CNS) drug delivery. We overview structural innovation of nanocarriers, improvements in targeting strategies, and nanotechnology‐enhanced brain imaging.
Qibin Liu, Zhuoqian Chen, Anthony Guiseppi‐Elie, Fanling Meng, Liang Luo   +4 more
wiley   +1 more source

Single-cell transcriptome sequencing reveals altered peripheral blood immune cells in patients with severe tuberculosis

European Journal of Medical Research
Tuberculosis is a serious global health burden, resulting in millions of deaths each year. Several circulating cell subsets in the peripheral blood are known to modulate the host immune response to Mycobacterium tuberculosis (Mtb) infection in different ...
Li Wang, Ya He, Peng Wang, Hai Lou, Haipeng Liu, Wei Sha   +5 more
doaj   +1 more source

Astaxanthin Alleviates Lung Injury by Regulating Oxidative Stress, Inflammatory Response, P2X7 Receptor, NF‐κB, Bcl‐2, and Caspase‐3 in LPS‐Induced Endotoxemia

Environmental Toxicology, EarlyView.
ABSTRACT Sepsis remains the leading cause of multiple‐organ injury due to endotoxemia. Astaxanthin (ASTA), widely used in marine aquaculture, has an extraordinary potential for antioxidant and anti‐inflammatory activity. Purinergic receptor (e.g., P2X7R) activation is a powerful signaling in the modulation of inflammation.
Seckin Ozkanlar, Yunusemre Ozkanlar, Adem Kara, Elif Dalkilinc   +3 more
wiley   +1 more source

Evolution of Eligibility Criteria in Inflammatory Bowel Disease Clinical Trials: A Clinical Trial Databank Analysis

United European Gastroenterology Journal, EarlyView.
ABSTRACT Background Eligibility criteria in clinical trials have been criticised for being overly restrictive without clinical justification. Objective We aimed to investigate the types, evolution, and current status of eligibility criteria in clinical trials for inflammatory bowel diseases (IBD).
An Outtier, Rosanne Janssens, Liese Barbier, João Sabino, Bram Verstockt, Séverine Vermeire, Isabelle Huys, Marc Ferrante   +7 more
wiley   +1 more source

Bronchoalveolar lavage studies in pulmonary tuberculosis (editorial) [PDF]

, 1997
Bronchoalveolar lavage (BAL) studies are useful to assess the lower respiratory tract inflammation and to study the pathogenesis of various lung diseases (1). Even though potent chemotherapeutic regimens are available currently to treat patients with
Vijayan, V K
core  

Non-contact Lung Disease Classification via OFDM-based Passive 6G ISAC Sensing [PDF]

arXiv
This paper is the first to present a novel, non-contact method that utilizes orthogonal frequency division multiplexing (OFDM) signals (of frequency 5.23 GHz, emitted by a software defined radio) to radio-expose the pulmonary patients in order to differentiate between five prevalent respiratory diseases, i.e., Asthma, Chronic obstructive pulmonary ...
arxiv  

Delay in DOTS for new pulmonary tuberculosis patient from rural area of Wardha District, India [PDF]

, 2010
Vast majority of active tuberculosis patients seeks treatment, do so promptly, still many patients spend a great deal of time and money “shopping for health” and too often they do not receive either accurate diagnosis or effective treatment, despite ...
Bawankule, S, Gaidhane, A, Khatib , N, Quazi, SZ   +3 more
core   +1 more source

Avoiding early diagnosis

Journal of General and Family Medicine, EarlyView.
Takao Wakabayashi, Goh Keng Wee, Mikinosuke Ishibashi, Yoshiki Akiyama, Naoki Kanda, Tomoyuki Watanabe   +5 more
wiley   +1 more source

Proliferative and neoplastic aural pinna masses in a collection of African giant pouched rats (Cricetomys ansorgei)

Veterinary Record Case Reports, EarlyView.
Abstract This case series describes aural lesions occurring in five African giant pouched rats (Cricetomys ansorgei) residing at a single zoological institution in southern California. Age of onset ranged from 3 to 7 years. Lesions occurred as single or multiple masses on one or both ears. A single case also developed a nasal mass.
Amanda Burke, Alison Righton, Tess Rooney, Matt Marinkovich, Garrett Fraess   +4 more
wiley   +1 more source

CXCL9/CXCL10 as biomarkers the monitoring of treatment responses in Pulmonary TB patients: a systematic review and meta-analysis

BMC Infectious Diseases
Summary Background Tuberculosis (TB) remains a persistent threat to global public health and traditional treatment monitoring approaches are limited by their potential for contamination and need for timely evaluation.
Zeyou Wei, Yuanjin Chen, Pengyan Dong, Zhihui Liu, Xiaomin Lai, Nan Wang, Hua Li, Qi Wang, Lan Tao, Ning Su, Yu Yang, Fanrong Meng   +11 more
doaj   +1 more source