Results 31 to 40 of about 149,015 (244)

THE DIAGNOSIS OF PULMONARY TUBERCULOSIS [PDF]

open access: yesBMJ, 1900
This may be a matter of considerable ease, or one of extreme difficulty, depending on the stage of the disease and the nature of the pathologic conditions. Let us first consider its diagnosis at an early stage. Tuberculosis is an infection, and as is the rule with infections, it occasions a rise of temperature even at its incipiency. Except very rarely,
openaire   +3 more sources

Mitochondrial Regulation of CD8⁺ T Cells: Mechanisms and Therapeutic Modulation

open access: yesAdvanced Science, EarlyView.
This article comprehensively explores the pivotal role of mitochondrial function in CD8⁺ T cell immunotherapy. It highlights how mitochondrial dynamics regulate T cell activation, differentiation, and persistence, and how mitochondrial dysfunction leads to immune exhaustion and impaired antitumor/antiviral responses.
Xu Chen   +7 more
wiley   +1 more source

Evaluation of Mycobacterium tuberculosis specific antigen-stimulated CD27−CD38+IFN-γ+CD4+ T cells for discrimination of active tuberculosis

open access: yesBMC Infectious Diseases, 2022
Background Active tuberculosis (ATB) originates from primary Mycobacterium tuberculosis (MTB) infection or reactivation of latent tuberculosis. Besides bacteriological examination, MTB-reactive immunocytes detection can be an alternative testing for ...
Yong Fang   +8 more
doaj   +1 more source

Comparison of the diagnostic yield of transbronchial lung biopsies by forceps and cryoprobe in diffuse parenchymal lung disease

open access: yesAfrican Journal of Thoracic and Critical Care Medicine, 2023
Background. Transbronchial lung cryobiopsy (TBLC) in the diagnosis of diffuse parenchymal lung disease (DPLD) has shown a promising yield in recent times, with low post-procedural mortality and morbidity. Objectives.
M S Khot   +6 more
doaj   +1 more source

A Novel nor@DHB Matrix for Direct Microbial Analysis in Lung Cancer Tissues

open access: yesAdvanced Science, EarlyView.
Integrated matrix‐assisted laser desorption/ionization mass spectrometry workflow quantifies intratumoral microbes in lung cancer through lipopolysaccharide/lipid A extraction from biopsies. The novel ionic matrix called norharmane conjugated to 2,5‐dihydroxybenzoic acid enhances lipid A ionization, enabling direct detection of bacterial genera ...
Liang Shan   +12 more
wiley   +1 more source

Mycobacterium tuberculosis suppresses host antimicrobial peptides by dehydrogenating L-alanine

open access: yesNature Communications
Antimicrobial peptides (AMPs), ancient scavengers of bacteria, are very poorly induced in macrophages infected by Mycobacterium tuberculosis (M. tuberculosis), but the underlying mechanism remains unknown.
Cheng Peng   +21 more
doaj   +1 more source

Host-directed therapy against mycobacterium tuberculosis infections with diabetes mellitus

open access: yesFrontiers in Immunology
Tuberculosis (TB) is caused by the bacterial pathogen Mycobacterium tuberculosis (MTB) and is one of the principal reasons for mortality and morbidity worldwide.
Li Zhao   +7 more
doaj   +1 more source

Performance of the MeltPro TB assay as initial test for diagnosis of pulmonary tuberculosis with drug-resistance detection

open access: yesMolecular Medicine, 2023
Background The MeltPro TB assay (MeltPro) is a molecular rapid diagnostic test designed for detecting resistance to antituberculosis drugs. However, the performance of MeltPro as an initial diagnostic test for simultaneously detecting the presence of ...
Zhi-bin Liu   +10 more
doaj   +1 more source

PULMONARY TUBERCULOSIS

open access: yesThe American Journal of the Medical Sciences, 1923
Mode of access: Internet.
openaire   +1 more source

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