Results 51 to 60 of about 206,114 (317)

Pneumocystis jirovecii pneumonia in a patient with Mycobacterium intracellulare pulmonary disease: a case report

open access: yesBMC Infectious Diseases
This report details the case of a 77-year-old female with Mycobacterium intracellulare pulmonary disease and history of bladder tumor surgery. The patient initially presented to our hospital with a one-day history of fever. After receiving antibiotic and
Xiaoni Zhou   +7 more
doaj   +1 more source

PULMONARY TUBERCULOSIS

open access: yesThe American Journal of the Medical Sciences, 1923
Mode of access: Internet.
openaire   +1 more source

Optimizing pathological diagnosis of tuberculosis: qPCR outperforms acid-fast staining in formalin-fixed paraffin-embedded tissues and enables resistance profiling

open access: yesFrontiers in Medicine
Background and ObjectiveAccurate detection of Mycobacterium tuberculosis (MTB) in formalin-fixed paraffin-embedded (FFPE) tissues remains a significant challenge in routine pathological practice.
Yan Hu   +4 more
doaj   +1 more source

Efficacy and safety of an innovative short-course regimen containing clofazimine for treatment of drug-susceptible tuberculosis: a clinical trial

open access: yesEmerging Microbes and Infections, 2023
In preclinical studies, a new antituberculosis drug regimen markedly reduced the time required to achieve relapse-free cure. This study aimed to preliminarily evaluate the efficacy and safety of this four-month regimen, consisting of clofazimine ...
Xubin Zheng   +18 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

open access: yesAdvanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa   +3 more
wiley   +1 more source

The granuloma in tuberculosis: dynamics of a host-pathogen collusion. [PDF]

open access: yes, 2012
A granuloma is defined as an inflammatory mononuclear cell infiltrate that, while capable of limiting growth of Mycobacterium tuberculosis, also provides a survival niche from which the bacteria may disseminate.
Ulrich E. Schaible   +5 more
core   +1 more source

Mycobacterium tuberculosis suppresses host antimicrobial peptides by dehydrogenating L-alanine

open access: yesNature Communications
Antimicrobial peptides (AMPs), ancient scavengers of bacteria, are very poorly induced in macrophages infected by Mycobacterium tuberculosis (M. tuberculosis), but the underlying mechanism remains unknown.
Cheng Peng   +21 more
doaj   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

open access: yesAdvanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao   +16 more
wiley   +1 more source

REST IN PULMONARY TUBERCULOSIS. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1906
I wish to make a plea addressed to the general practitioner for the routine employment of rest in the open air in all active or partially arrested cases of tuberculosis. In the vast majority of cases the general practitioner is the man who is called on to diagnose and to treat these patients, and as he has been lectured, criticized and cajoled into ...
openaire   +2 more sources

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