Results 51 to 60 of about 975,760 (305)

Pneumocystis jirovecii pneumonia in a patient with Mycobacterium intracellulare pulmonary disease: a case report

BMC Infectious Diseases
This report details the case of a 77-year-old female with Mycobacterium intracellulare pulmonary disease and history of bladder tumor surgery. The patient initially presented to our hospital with a one-day history of fever. After receiving antibiotic and
Xiaoni Zhou, Xinhua Xiao, Yuying Wu, Jun Wang, Zhiyun Pan, Han Wang, Xiaohui Luo, Zhi Yao   +7 more
doaj   +1 more source

Optimizing pathological diagnosis of tuberculosis: qPCR outperforms acid-fast staining in formalin-fixed paraffin-embedded tissues and enables resistance profiling

Frontiers in Medicine
Background and ObjectiveAccurate detection of Mycobacterium tuberculosis (MTB) in formalin-fixed paraffin-embedded (FFPE) tissues remains a significant challenge in routine pathological practice.
Yan Hu, Peng Liu, Minhui Mei, Chao Quan, Qiliang Liu   +4 more
doaj   +1 more source

Targeting the NR1D1–IGF2BP2–V‐ATPase Axis With Hybrid Nanovesicles Restores Macrophage Rhythms to Reverse Sepsis‐Induced Immunosuppression

Advanced Science, EarlyView.
Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Lang Chen, Wenyi Lin, Lang Jiang, Xuehui Gao, Chenyan Yu, Jili Han, Zhenping Liu, Xuefeng Li, Mei He, Chang Li, Qilan Li, Chaoying Song, Jiqian Xu, You Shang   +13 more
wiley   +1 more source

Characteristics of tuberculosis contact of children with pulmonary tuberculosis [PDF]

, 2006
Background Children with tuberculosis (TB) are often asymptomatic, so that if TB is diagnosed in a child, an adult contact should be looked for. We realize the importance of TB control by breaking the chain of transmission, so identification of ...
Laila, Retno Murti, Sidhartani, Magdalena   +1 more
core   +1 more source

Efficacy of the Xpert Mycobacterium tuberculosis/rifampicin assay for diagnosing sputum-smear negative or sputum-scarce pulmonary tuberculosis in bronchoalveolar lavage fluid

International Journal of Infectious Diseases, 2021
Objective: To evaluate he diagnostic performance of the Xpert Mycobacterium tuberculosis/Rifampin (MTB/RIF) assay in bronchoalveolar lavage fluid (BALF).
Juan Yang, Yanheng Shen, Lei Wang, LiXia Ju, Xiaocui Wu, Peng Wang, Xiaohui Hao, Qin Sun, Fangyou Yu, Wei Sha   +9 more
doaj   +1 more source

REST IN PULMONARY TUBERCULOSIS. [PDF]

JAMA: The Journal of the American Medical Association, 1906
I wish to make a plea addressed to the general practitioner for the routine employment of rest in the open air in all active or partially arrested cases of tuberculosis. In the vast majority of cases the general practitioner is the man who is called on to diagnose and to treat these patients, and as he has been lectured, criticized and cajoled into ...
openaire   +2 more sources

Performance of the 2007 WHO Algorithm to diagnose Smear-negative Pulmonary Tuberculosis in a HIV prevalent setting [PDF]

, 2012
The 2007 WHO algorithm for diagnosis of smear-negative pulmonary tuberculosis (PTB) including Mycobacterium tuberculosis (MTB) culture was evaluated in a HIV prevalent area of ...
Maryline Bonnet, Helena Huerga, Bonnet, M., Elisa Ardizzoni, Jeremiah Chakaya (109546), Chakaya, J, Bonnet, M, Maryline Bonnet (89522), Mathieu Bastard, Mathieu Bastard (109538), Ardizzoni, E, Francis Varaine, Joseph Sitienei, Jeremiah Chakaya, Bastard, M., Eric Okwaro (109536), Okwaro, E., Sitienei, J., Varaine, F, Chakaya, J., Eric Okwaro, Francis Varaine (109532), Okwaro, E, Helena Huerga (109527), Sitienei, J, Huerga, H., Elisa Ardizzoni (109540), Bastard, M, Ardizzoni, E., Varaine, F., Huerga, H, Joseph Sitienei (109543), Chakaya Jeremiah, Sitienei Joseph, Huerga Helena, Okwaro Eric, Bastard Mathieu, Varaine Francis, Bonnet Maryline, Ardizzoni Elisa   +39 more
core   +2 more sources

OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD

Advanced Science, EarlyView.
This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li, Jingyue Song, Kaili Ma, Shunan Tang, Shuqian Wang, Wenya Ji, Chen Lu, Ting Zhang, Huaping Zheng, Xiaowei Zheng, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

Relationship between IFN-gamma and skin test responsiveness to Mycobacterium tuberculosis PPD in healthy, non-BCG-vaccinated young adults in Northern Malawi. [PDF]

, 2001
SETTING: Rural northern Malawi, where vaccination with BCG Glaxo (1077) provides protection against leprosy but not against pulmonary tuberculosis. OBJECTIVE: To evaluate the patterns of responsiveness to purified protein derivative of Mycobacterium ...
Fine PEM, Ngwira, B, Blackwell, JM, Sichali, L, Chaguluka, S, Jarman, E, Dockrell, HM, Black, GF, Mwaungulu, L, Warndorff, DK, Weir, RE, Bliss, L, Floyd, S   +12 more
core   +3 more sources

Mycobacterium tuberculosis suppresses host antimicrobial peptides by dehydrogenating L-alanine

Nature Communications
Antimicrobial peptides (AMPs), ancient scavengers of bacteria, are very poorly induced in macrophages infected by Mycobacterium tuberculosis (M. tuberculosis), but the underlying mechanism remains unknown.
Cheng Peng, Yuanna Cheng, Mingtong Ma, Qiu Chen, Yongjia Duan, Shanshan Liu, Hongyu Cheng, Hua Yang, Jingping Huang, Wenyi Bu, Chenyue Shi, Xiangyang Wu, Jianxia Chen, Ruijuan Zheng, Zhonghua Liu, Zhe Ji, Jie Wang, Xiaochen Huang, Peng Wang, Wei Sha, Baoxue Ge, Lin Wang   +21 more
doaj   +1 more source