Results 61 to 70 of about 206,114 (317)

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

Spatio-temporal distribution of Mycobacterium tuberculosis complex strains in Ghana [PDF]

, 2016
BACKGROUND: There is a perception that genomic differences in the species/lineages of the nine species making the Mycobacterium tuberculosis complex (MTBC) may affect the efficacy of distinct control tools in certain geographical areas.
Yeboah-Manu, Dorothy, K. A. Koram (3088575), Asante-Poku, A., S. Osei-Wusu (3088569), I. D. Otchere (3088587), Forson, A., Dorothy Yeboah-Manu (120059), Osei-Wusu, S., Gagneux, Sebastien, Danso, E., A. Forson (3088581), A. Asante-Poku (3088584), I D Otchere, E. Danso (3088578), A Asante-Poku, Asare, P., P Asare, Koram, K. A., S Osei-Wusu, E Danso, Sebastien Gagneux (149824), A Forson, K A Koram, Sebastien Gagneux, P. Asare (3088572), Dorothy Yeboah-Manu, Otchere, I. D.   +26 more
core   +1 more source

Current landscape of exosomes in tuberculosis development, diagnosis, and treatment applications

Frontiers in Immunology
Tuberculosis (TB), caused by the bacterial pathogen Mycobacterium tuberculosis (MTB), remains one of the most prevalent and deadly infectious diseases worldwide. Currently, there are complex interactions between host cells and pathogens in TB. The onset,
Xuezhi Sun, Wei Li, Li Zhao, Ke Fan, Fenfen Qin, Liwen Shi, Feng Gao, Chunlan Zheng   +7 more
doaj   +1 more source

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

Optimized anti-tuberculosis duration for drug-susceptible pulmonary tuberculosis-diabetes mellitus comorbidities: study protocol for a multicenter randomized controlled trial

BMC Pulmonary Medicine
Background The coexistence of tuberculosis (TB) and type 2 diabetes mellitus (DM) presents unique challenges in treatment optimization and management, given the mutual exacerbation of disease processes.
Peize Zhang, Huaifang Shi, Yongping Xie, Jiemei Liang, Qiumeng Hu, Liang Fu, Yuxiang Wang, Jie Tan, Senlin Zhan, Hongjuan Qin, Guanghui Xu, Guofang Deng   +11 more
doaj   +1 more source

Host-directed therapy against mycobacterium tuberculosis infections with diabetes mellitus

Frontiers in Immunology
Tuberculosis (TB) is caused by the bacterial pathogen Mycobacterium tuberculosis (MTB) and is one of the principal reasons for mortality and morbidity worldwide.
Li Zhao, Ke Fan, Xuezhi Sun, Wei Li, Fenfen Qin, Liwen Shi, Feng Gao, Chunlan Zheng   +7 more
doaj   +1 more source

SERS Facemask for Rapid and Portable Sensing Mycobacterium Tuberculosis Antigens for TB Screening

Advanced Science, EarlyView.
Our study introduced an Au─Ag embedded covalent organic framework (U@COF) ‐mediated facemask for sensing TB antigen ESAT‐6/CFP‐10 complex in clinical droplet samples toward TB screening. Practical analysis of clinical samples demonstrated the availability of our facemask, which is capable of identifying the TB subjects (N = 17) from healthy candidates (
Lingzhi Chen, Jiaqi Yu, Jing Xu, Lingqi Chen, Ninghao Zhang, Wenrui Li, Runmin Zeng, Xiaomin Luo, Yiqun Chang, Jiayin Lai, Wenshi Huang, Xiaochen Liang, Ting Zhao, Shanze Chen, Huaihong Cai, Yanguang Cong, Pinghua Sun, Jiang Pi, Xueqin Huang, Haibo Zhou, Junxia Zheng   +20 more
wiley   +1 more source

Tuberculosis diagnostics and biomarkers: needs, challenges, recent advances, and opportunities

, 2012
Tuberculosis is unique among the major infectious diseases in that it lacks accurate rapid point-of-care diagnostic tests. Failure to control the spread of tuberculosis is largely due to our inability to detect and treat all infectious cases of pulmonary
Grobusch, Martin P., Pletschette, Michel, Mchugh, Timothy D., Schwank, Samana, Zumla, A, McNerney, R., Squire, S. Bertel, Ford, Nathan, Kim, P.S., Marais, B, Squire, S B, Migliori, Giovanni Batista, Bates, M, McHugh, Timothy D, Grobusch, M.P., McNerney, R, Migliori, G-B, Migliori, Giovanni-Batista, Squire, Bertie, Lawn, S, O'Grady, J, Chakaya, J., Lawn, Steve, Mwaba, Peter, Harari, Alexandre, Memish, Z, Harari, A., Cox, Helen, Abubakar, I, Ford, N, Hoelscher, Michael, Chakaya, J, Kim, Peter, Zijenah, L, Casenghi, M., Grobusch, M P, Casenghi, Martina, McHugh, T D, Marais, B., Weyer, K., Pantaleo, Giuseppe, Schito, Marco, Pletschette, M, Abubakar, Ibrahim, Atun, Rifat, Weyer, K, Mchugh, Timothy, O'Grady, J., Schwank, S, Mwaba, P., Grobusch, Martin P, Mwaba, P, Casenghi, M, Lawn, S., Squire, S, Zijenah, L., Ditui, Lucica, Cox, H., Pantaleo, G, Kim, P S, Schito, M, Weyer, Karin, O'Grady, Justin, Atun, R, Kim, Peter S, Harari, A, Grobusch, Martin, Abubakar, I., Zijenah, Lynn, Bates, Matthew, Memish, Ziad, Cox, H, Pletschette, M., Memish, Z., Schwank, S., Squire, S Bertel, Migliori, G.B., Ditui, L., McNerney, Ruth, Hoelscher, M., McHugh, T.D., Bates, M., Swaminathan, Soumya, Marais, Ben, Maeurer, Markus, Pantaleo, G., Zumla, A., Maeurer, M, Swaminathan, S, Kim, Peter S., Ditui, L, Hoelscher, M, Squire, S.B., Chakaya, Jeremiah, Ford, N., Zumla, Alimuddin, Schito, M., Maeurer, M., Swaminathan, S., Atun, R.   +99 more
core   +1 more source

Bilateral SERS‐Microneedle Patch for Co‐Diagnosis of Diabetes Mellitus and Tuberculosis Comorbidity

Advanced Science, EarlyView.
Our study introduced a U@mP@Au‐mediated bilateral SERS‐microneedle patch for analyzing glucose levels from ISF and sensitively detecting TB biomarkers from sputum, respectively. This integrated dual‐analyte detecting platform can be used for co‐diagnosis of diabetes mellitus (DM) and tuberculosis (TB) comorbidity, which was demonstrated in ex vivo ...
Xueqin Huang, Lingzhi Chen, Jing Xu, Jiaqi Yu, Shanze Chen, Huaihong Cai, Yanguang Cong, Pinghua Sun, Jiang Pi, Lang Rao, Jierong Chen, Junxia Zheng, Haibo Zhou   +12 more
wiley   +1 more source

Improved recovery of Mycobacterium tuberculosis from children using the microscopic observation drug susceptibility method.

, 2006
OBJECTIVE: The diagnosis of pulmonary tuberculosis presents challenges in children, because symptoms are nonspecific, sputa are not accessible, and Mycobacterium tuberculosis cultures and smears often are negative.
Luz Caviedes, Oberhelman, Richard A, Gilman, Robert H, Giselle Soto-Castellares, Carlton Evans, Castillo, Maria E, Robert H. Gilman, Moore, David AJ, David A.J. Moore, Maria E. Castillo, Patricia Kissinger, Richard A. Oberhelman, Caviedes, Luz, Evans, Carlton, Soto-Castellares, Giselle, Kissinger, Patricia   +15 more
core   +1 more source