Results 41 to 50 of about 288,465 (306)

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

THE CLASSIFICATION OF PULMONARY TUBERCULOSIS [PDF]

The Lancet, 1920
n ...
openaire   +3 more sources

Optical Detection of Volatile Organic Compounds: A Review of Methods and Functionalized Sensing Materials

Advanced Optical Materials, EarlyView.
The focus on volatile organic compounds (VOCs) detection is dictated by the increasing awareness of their impact on human health. In addition, VOCs are increasingly considered novel for early diagnosis of diseases. Among various types of VOC sensor devices, optical detectors play an essential role, offering excellent versatility, fast response time ...
Aleksandra Hernik, Jorid Smets, Zhe Wang, Yuliya Semenova, Jin‐Chong Tan, Rob Ameloot, Izabela Naydenova   +6 more
wiley   +1 more source

THE DIAGNOSIS OF PULMONARY TUBERCULOSIS [PDF]

BMJ, 1900
This may be a matter of considerable ease, or one of extreme difficulty, depending on the stage of the disease and the nature of the pathologic conditions. Let us first consider its diagnosis at an early stage. Tuberculosis is an infection, and as is the rule with infections, it occasions a rise of temperature even at its incipiency. Except very rarely,
openaire   +3 more sources

Cathepsin K Aggravates Pulmonary Fibrosis Through Promoting Fibroblast Glutamine Metabolism and Collagen Synthesis

Advanced Science, EarlyView.
CTSK plays a critical role in pulmonary fibrosis. Excessive CTSK accumulation interacts with SNX9 to enhance TGF‐β1‐induced SMAD3 activation and GLS1 expression in fibroblasts, driving glutamine metabolism for collagen biosynthesis and exacerbating pulmonary fibrosis.
Mengting Chen, Xiaoxiao Meng, Yong Zhu, Dapeng Wang, Mengmeng Wang, Ziyuan Wang, Xue Tian, Jiaxiang Zhang, Zhiying Yue, Zhengfeng Yang, Ruilan Wang   +10 more
wiley   +1 more source

The infectiousness of tuberculosis patients coinfected with HIV [PDF]

, 2008
The current understanding of airborne tuberculosis (TB) transmission is based on classic 1950s studies in which guinea pigs were exposed to air from a tuberculosis ward.
A. Roderick Escombe, Alland, Armando Gonzalez, Balasubramanian, Beggs, Behr, Bock, Bonnet, Borgdorff, Burgos, Calder, Capewell, Carlos Martínez, Carlton A Evans, Catanzaro, Catherine J Noakes, Caviedes, Caviedes, Cox, Cruciani, David A. J Moore, Desjardin, Eduardo Ticona, Escombe, Escombe, Escombe, Espinal, Fennelly, Fennelly, Gandhi, Garcí, Jindani, Jon S Friedland, Kamerbeek, Loudon, Luz Caviedes, Malasky, Marcos Navincopa, Nardell, Palmero, Patricia Sheen, Peter Wilson, Riley, Riley, Riley, Robert H Gilman, Rose, Rouillon, Shamputa, Snider, Sultan, Teixeira, van Soolingen, William Pan   +53 more
core   +7 more sources

Targeting Cystine Metabolism in the Lung Cancer Environment Enhances the Efficacy of Immune Checkpoint Inhibition

Advanced Science, EarlyView.
The tumor‐associated macrophages (TAMs) in lung cancer tissues exhibit active cystine metabolism. Restricting cystine concentration in macrophages induces M1 phenotypic polarization and upregulation of PD‐L1 expression through the GSH‐NF‐κB signaling pathway.
Yun Xu, Shumin Li, Jiaji Wu, Shumin Xu, Mo Shen, Chenyang Wang, Lundqvist Andreas, Jianghao Yu, Zhiyong Xu, Yueli Shi, Nana Liu, Yunke Yang, Jiangnan Zhao, Ying Yang, Pingli Wang, Peng Yi, Jin Cheng, Junhui Sun, Mengshu Li, Peng Xiao, Kai Wang   +20 more
wiley   +1 more source

Mycobacterium tuberculosis suppresses host antimicrobial peptides by dehydrogenating L-alanine

Nature Communications
Antimicrobial peptides (AMPs), ancient scavengers of bacteria, are very poorly induced in macrophages infected by Mycobacterium tuberculosis (M. tuberculosis), but the underlying mechanism remains unknown.
Cheng Peng, Yuanna Cheng, Mingtong Ma, Qiu Chen, Yongjia Duan, Shanshan Liu, Hongyu Cheng, Hua Yang, Jingping Huang, Wenyi Bu, Chenyue Shi, Xiangyang Wu, Jianxia Chen, Ruijuan Zheng, Zhonghua Liu, Zhe Ji, Jie Wang, Xiaochen Huang, Peng Wang, Wei Sha, Baoxue Ge, Lin Wang   +21 more
doaj   +1 more source

Current landscape of exosomes in tuberculosis development, diagnosis, and treatment applications

Frontiers in Immunology
Tuberculosis (TB), caused by the bacterial pathogen Mycobacterium tuberculosis (MTB), remains one of the most prevalent and deadly infectious diseases worldwide. Currently, there are complex interactions between host cells and pathogens in TB. The onset,
Xuezhi Sun, Wei Li, Li Zhao, Ke Fan, Fenfen Qin, Liwen Shi, Feng Gao, Chunlan Zheng   +7 more
doaj   +1 more source

PULMONARY TUBERCULOSIS

The American Journal of the Medical Sciences, 1923
Mode of access: Internet.
openaire   +1 more source