Results 51 to 60 of about 1,739,773 (346)

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

The diagnostic performance of endobronchial ultrasound with Xpert MTB/RIF Ultra in smear-negative pulmonary tuberculosis

BMC Infectious Diseases, 2023
Objective This study investigated the diagnostic performance of endobronchial ultrasound with Xpert MTB/RIF Ultra (Ultra) for detecting smear-negative pulmonary tuberculosis (TB).
Lan Yao, Shanhao Chen, Wei Sha, Ye Gu
doaj   +1 more source

Efficacy and safety of an innovative short-course regimen containing clofazimine for treatment of drug-susceptible tuberculosis: a clinical trial

Emerging Microbes and Infections, 2023
In preclinical studies, a new antituberculosis drug regimen markedly reduced the time required to achieve relapse-free cure. This study aimed to preliminarily evaluate the efficacy and safety of this four-month regimen, consisting of clofazimine ...
Xubin Zheng, Xuwei Gui, Lan Yao, Jun Ma, Yifan He, Hai Lou, Jin Gu, Ruoyan Ying, Liping Chen, Qin Sun, Yidian Liu, Chih-Ming Ho, Bai-Yu Lee, Daniel L. Clemens, Marcus A. Horwitz, Xianting Ding, Xiaohui Hao, Hua Yang, Wei Sha   +18 more
doaj   +1 more source

Use of Xpert MTB/RIF in Decentralized Public Health Settings and Its Effect on Pulmonary TB and DR-TB Case Finding in India [PDF]

, 2015
Background Xpert MTB/RIF, the first automated molecular test for tuberculosis, is transforming the diagnostic landscape in high-burden settings. This study assessed the impact of up-front Xpert MTB/RIF testing on detection of pulmonary tuberculosis (PTB)
Alavadi, U, Arinaminpathy, N, Babre, A, Boehme, C, Denkinger, C, Dewan, PK, Ghedia, M, Gray, C, Gupta, RS, Kulsange, S, Paramasivan, CN, Parmar, M, Raizada, N, Ramachandran, R, Sachdeva, KS, Sreenivas, A, Thakur, R, Vadera, B, Van den Hof, S, Van't Hoog, AH   +19 more
core   +1 more source

Development and Validation of a Deep Learning–based Automatic Detection Algorithm for Active Pulmonary Tuberculosis on Chest Radiographs

Clinical Infectious Diseases, 2018
Background Detection of active pulmonary tuberculosis on chest radiographs (CRs) is critical for the diagnosis and screening of tuberculosis. An automated system may help streamline the tuberculosis screening process and improve diagnostic performance ...
Eui Jin Hwang, Sunggyun Park, K. Jin, Jung Im Kim, So Young Choi, Jong Hyuk Lee, J. Goo, Jaehong Aum, J. Yim, C. Park, Dong Hyeon Woo Choi In Pyung Yong Sub Lim Kim Jae Yeon Kim Woo Choi Hwang Song Lim Kim Wi Oh Kang, Dong Hyeon Kim, Woo Woo, C. Choi, I. Hwang, Y. Song, Lim Lim, K. Kim, J. Wi, Su Suk Oh, Mi-Jin Kang   +20 more
semanticscholar   +1 more source

Clinical Outcomes of Patients Within the Rheumatoid Arthritis Care Pathway Cohort at a Tertiary Care Integrated Delivery Network: A Comparison to Usual Care

Arthritis Care &Research, EarlyView.
Objective We aimed to compare clinical outcomes between patients in the Allegheny Health Network rheumatoid arthritis (RA) care pathway and patients receiving usual care. Methods The care pathway initiative implements guideline‐based best practice alongside multidisciplinary team‐based care.
Tarun Sharma, Tyson S. Barrett, Teigan Dwyer, Nancy Campbell, Jessica Heintzinger, Ellen Kraemer, Adam Dore, Susan Manzi   +7 more
wiley   +1 more source

The regulation and potential role of interleukin-32 in tuberculous pleural effusion

Frontiers in Immunology
The possible protective effect of interleukin-32 (IL-32) in Mycobacterium tuberculosis (Mtb) infection has been indicated. However, few studies have been focused on IL-32 in tuberculosis patients.
Xuan Wang, Chengqing Yang, Chao Quan, Jun Li, Yan Hu, Peng Liu, Lulu Guan, Li Li, Li Li   +8 more
doaj   +1 more source

Model of Empowerment to Improve Autonomy Directly Observed Treatment (DOT) Tuberculosis Patients [PDF]

, 2016
Empowerment as not yet optimal health promotion efforts done to enhance the autonomy of Directly Observed Treatment (DOT), which affect the success of the recovery of patients with pulmonary tuberculosis.
Abdullah, E. (Endang), Hamidah, H. (Hamidah), Khariroh, S. (Syamilatul), Soedirham, O. (Oedojo)   +3 more
core   +2 more sources

Cell Calcification Models and Their Implications for Medicine and Biomaterial Research

Advanced Healthcare Materials, EarlyView.
Calcification, is the process by which the tissues containing minerals are formed, occurring during normal physiological processes, or in pathological conditions. Here, it is aimed to give a comprehensive overview of the range of cell models available, and the approaches taken by these models, highlighting when and how methodological divergences arise,
Luke Hunter, Caterina Vanelli Coralli, Robert Dzhanaev, Aaron Morgan, Willi Jahnen‐Dechent, Sergio Bertazzo   +5 more
wiley   +1 more source

Pneumocystis jirovecii pneumonia in a patient with Mycobacterium intracellulare pulmonary disease: a case report

BMC Infectious Diseases
This report details the case of a 77-year-old female with Mycobacterium intracellulare pulmonary disease and history of bladder tumor surgery. The patient initially presented to our hospital with a one-day history of fever. After receiving antibiotic and
Xiaoni Zhou, Xinhua Xiao, Yuying Wu, Jun Wang, Zhiyun Pan, Han Wang, Xiaohui Luo, Zhi Yao   +7 more
doaj   +1 more source