Results 51 to 60 of about 136,566 (147)

Digital Image Analysis of Heterogeneous Tuberculosis Pulmonary Pathology in Non-Clinical Animal Models using Deep Convolutional Neural Networks. [PDF]

open access: yesSci Rep, 2020
Asay BC   +12 more
europepmc   +1 more source

Real‐world safety and effectiveness of guselkumab in patients with psoriasis: A post‐marketing surveillance study through up to week 52 in Japan

open access: yesThe Journal of Dermatology, EarlyView.
Abstract Guselkumab is a monoclonal antibody that binds to the p19 subunit of interleukin‐23 and inhibits its downstream signaling. The safety profile of guselkumab and its superior efficacy over placebo and adalimumab for the treatment of patients with moderate‐to‐severe psoriasis were reported in phase 3 studies conducted within and outside Japan. To
Yayoi Tada   +6 more
wiley   +1 more source

Patient–Provider Race Concordance and Primary Care Suicide Risk Screening in the Veterans Health Administration

open access: yesHealth Services Research, EarlyView.
ABSTRACT Objective To evaluate the association between patient–provider race concordance and the likelihood of being screened for suicide risk in Veterans Health Administration (VA) primary care settings. Study Setting and Design In November 2020, the VA expanded its national suicide risk identification strategy to include an annual universal suicide ...
Linda Diem Tran   +4 more
wiley   +1 more source

Radiological Insights Into the Pericardium: A Comprehensive Review

open access: yesJournal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT The pericardium is not simply a two‐layered membrane surrounding the heart and great vessels. Pericardial effusion is the most common manifestation of various pathological conditions involving the pericardium. Therefore, we are tempted to think of the pericardium as a virtual space containing only fluid, but it can also contain solid and ...
Felipe Aluja‐Jaramillo   +4 more
wiley   +1 more source

The 15‐Year Survival Advantage: Immune Resilience as a Salutogenic Force in Healthy Aging

open access: yesAging Cell, EarlyView.
Human aging shows puzzling diversity: similar aging rates yet vastly different health outcomes. Our study of ~17,500 people revealed a health‐promoting trait (more common in women) linked to strong immune resilience and high expression of TCF7, a key immune gene. This trait enables individuals to fight infections like COVID‐19 more effectively, respond
Muthu Saravanan Manoharan   +176 more
wiley   +1 more source

Integrated Efficacy and Safety Analysis of Abrocitinib in Adolescents With Moderate‐to‐Severe Atopic Dermatitis

open access: yesAllergy, EarlyView.
Data were included from adolescents with moderate‐to‐severe AD treated with the JAK1 inhibitor abrocitinib (200 mg/100 mg) across JADE clinical trials. Improvements in skin clearance (per EASI‐75) and itch (per PP‐NRS4) were maintained for up to 112 weeks with both abrocitinib doses.
Amy S. Paller   +13 more
wiley   +1 more source

Total Neoadjuvant Therapy Versus Conventional Neoadjuvant Therapy for Rectal Cancer: Cost Analysis in a Public Healthcare System

open access: yesANZ Journal of Surgery, EarlyView.
Costs of neoadjuvant therapy. ABSTRACT Purpose Total neoadjuvant therapy (TNT) has become the standard of care in locally advanced rectal cancer, but its economic impact is unclear. This study compares the cost of TNT with conventional neoadjuvant therapy (CNT), consisting of either short‐course radiotherapy or long‐course chemoradiotherapy, within a ...
Ishraq Murshed   +6 more
wiley   +1 more source

Perioperative Mechanical Circulatory Support for Cardiac Assistance in Thoracic Surgery: A Scoping Review

open access: yesArtificial Organs, EarlyView.
High‐risk cardiac patients may benefit from timely temporary mechanical circulatory support (tMCS) implantation to provide perioperative hemodynamic stabilization and circulatory support, thus enabling them to undergo life‐saving thoracic surgery. CPB: cardiopulmonary bypass; IABP: intra‐aortic balloon pump; tMCS: temporary mechanical circulatory ...
Viviana Teresa Agosta   +4 more
wiley   +1 more source

Generic Health‐Related Quality of Life of Children With Severe Peanut or Tree Nut Allergy

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim Food allergies may decrease health‐related quality of life. We assessed health‐related quality of life in Finnish children at risk of a severe peanut or tree nut allergy and their parents. Methods Study included children aged 3–15 years referred to Tampere University Hospital for suspected severe nut allergy.
Lasse Saarimäki   +8 more
wiley   +1 more source

Wound, pressure ulcer, and burn guidelines (2023)―4: Guidelines for the management of connective tissue disease/vasculitis‐associated skin ulcers, third edition

open access: yes
The Journal of Dermatology, EarlyView.
Yoshihide Asano   +27 more
wiley   +1 more source

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