Results 161 to 170 of about 1,198,187 (379)
Angewandte Chemie, EarlyView.Gromomycins represent a novel class of pentacyclic triterpene antibiotics with a unique biosynthetic pathway independent of the squalene route. These compounds exhibit potent activity against drug‐resistant Gram‐positive pathogens, including MRSA, and their unprecedented cyclization mechanism provides new insight into bacterial triterpene biosynthesis.
Stepan Tistechok +11 more
wiley +2 more sources
Complications leading to hospitalization due to consumption of anti-TB drugs in patients with tuberculosis in Gorgan, Iran (2007-12) [PDF]
, 2015 Background and Objective: Anti tuberculosis drugs therapy is the most effective method for controling the tuberculosis (TB). Early detection and appropriate treatment can prevent the TB-drug resistance.
Abbasi, A. +4 more
core
Pulmonary Tuberculosis Edge Diagnosis System Based on MindSpore Framework: Low-cost and High-precision Implementation with Ascend 310 Chip [PDF]
arXivPulmonary Tuberculosis (PTB) remains a major challenge for global health, especially in areas with poor medical resources, where access to specialized medical knowledge and diagnostic tools is limited. This paper presents an auxiliary diagnosis system for pulmonary tuberculosis based on Huawei MindSpore framework and Ascend310 edge computing chip ...
arxiv
An Evaluation of Tuberculosis Detection by Chest X-Ray Surveys [PDF]
, 1954 Robert J. Anderson +3 more
openalex +1 more source
Animal Models and Experimental Medicine, EarlyView.We collected the clinical isolates from all patients with pulmonary TB in Beijing from January 2016 to December 2021, A total of 8,512 clinical isolates were collected, and 261 RR‐TB strains were screened. We conducted the drug sensitivity tests and sequencing for LFX and MFX. The MICs of the strains were mainly distributed at 0.25 μg/mL for both drugs,
Wang Nenhan +7 more
wiley +1 more source
Efficient and Accurate Tuberculosis Diagnosis: Attention Residual U-Net and Vision Transformer Based Detection Framework [PDF]
arXivTuberculosis (TB), an infectious disease caused by Mycobacterium tuberculosis, continues to be a major global health threat despite being preventable and curable. This burden is particularly high in low and middle income countries. Microscopy remains essential for diagnosing TB by enabling direct visualization of Mycobacterium tuberculosis in sputum ...
arxiv
Animal Models and Experimental Medicine, EarlyView.The study successfully developed and validated a granulomatous liver injury model using a high‐dose BCG vaccine, simulating hepatic tuberculosis and autoimmune granulomatous liver diseases. Pharmacokinetic analysis examined the metabolic behavior of first‐line antitubercular drugs (isoniazid and rifampicin) and their main metabolites under conditions ...
Swati Sharma +8 more
wiley +1 more source
Tuberculosis in Malta and the school BCG vaccination programme [PDF]
, 2009 Background: Malta has one of the lowest incidence rates of tuberculosis in Europe and a comprehensive free-of-charge health care system. Objective: To investigate whether Malta satisfies the criteria recommended by the International Union Against ...
Cacciottolo, Joseph +2 more
core
Animal Models and Experimental Medicine, EarlyView.Cannabidiol (CBD) has numerous therapeutic properties, and is used to treat neurological conditions, such as neuroinflammation. However, the optimal dose of CBD to penetrate the brain requires further investigation. The primary aim of this study was to use a mouse model and the intrabuccal route for CBD administration to determine the optimal dose at ...
Oluwadara Pelumi Omotayo +4 more
wiley +1 more source