Results 281 to 290 of about 1,198,187 (379)

Is Mycobacterial InhA a Suitable Target for Rational Drug Design?

ChemMedChem, Accepted Article.
InhA, an NAD‐dependent enoyl‐acyl carrier protein reductase, is involved in the biosynthesis of mycolic acids, specific lipids to mycobacteria. InhA is the target of isoniazid, a first‐line anti‐tuberculosis drug used since the 1950s. Isoniazid is a prodrug that needs to be activated by the catalase‐peroxidase KatG.
Julien Rizet, Laurent Maveyraud, David Rengel, Valérie Guillet, Gabriel Publicola, Frédéric Rodriguez, Christian Lherbet, Lionel Mourey   +7 more
wiley   +1 more source

Adequacy of recommendations for adverse event management in national and international treatment guidelines for rifampicin-susceptible tuberculosis: a systematic review. [PDF]

EClinicalMedicine
Burman W, Ellis J, Hale G, Hill K.
europepmc   +1 more source

THE FUNCTION OF THE SPLEEN IN THE EXPERIMENTAL INFECTION OF ALBINO MICE WITH BACILLUS TUBERCULOSIS [PDF]

, 1914
Paul A. Lewis, Arthur Georges Margot
openalex   +1 more source

Hybrid Molecules as Efficient Drugs against Multidrug‐Resistant Malaria Parasites

ChemMedChem, EarlyView.
Among hybrid molecules currently developed as antimalarial drug candidates, emoquine‐1 exhibits high activity against all the multidrug‐resistant Plasmodium strains tested up to now, including artemisinin‐resistant quiescent parasites, critical parameters for promising antimalarial drugs. It is also curative in mouse malaria.
Anne Robert, Lucie Paloque, Jean‐Michel Augereau, Flore Nardella, Michel Nguyen, Bernard Meunier, Françoise Benoit‐Vical   +6 more
wiley   +1 more source

Lived experiences of women suffering from Tuberculosis in Kashmir: an interpretative phenomenological study. [PDF]

Front Glob Womens Health
Akhter R, Zargar WA, Paul FA.
europepmc   +1 more source

Expanding the Horizons of Phototherapy: A Review on the Superior Performance of Chalcogen‐Based Photosensitizers and Photothermal Agents for Cancer Therapy

ChemPhotoChem, EarlyView.
This review summarizes recent progress in chalcogen (S, Se, Te)‐incorporated photosensitizers and photothermal agent design. It explores synthetic strategies, spectroscopic and computational characterization, and in vitro/in vivo evaluations, showcasing the potential of these compounds for photodynamic and photothermal therapies.
Subhrakant Jena, Pranay Mohanty, Laxmipriya Dash, Himansu S. Biswal   +3 more
wiley   +1 more source

Clinical characteristics of active tuberculosis with pulmonary thromboembolism. [PDF]

BMC Pulm Med
Jia Y, Bo H, Tang L, Li Z, Yu Z, Hou Z, Yu H, Wu Q.   +7 more
europepmc   +1 more source

A comparative study of clinical outcomes and risk factors of tuberculosis in kidney transplant recipients from deceased donors. [PDF]

Eur J Med Res
Zhang H, Zhong M, Hu S, Tan L, Peng L, Xie X, Lan G.   +6 more
europepmc   +1 more source

Itinerant curriculum theory: People's theory against the field's epistemicidal ethos

The Curriculum Journal, EarlyView.
Abstract The field of curriculum studies suffers from a glaring theoretical impasse. Much of this impasse has been rightly attributed to the triumphalism of the neoliberal wave that has massacred the educational hemisphere with policies and practices that reduce pedagogy to an instrumentalist praxis directly associated with the thirsty desires and ...
João M. Paraskeva
wiley   +1 more source

A rare case of tuberculous cystitis and pulmonary tuberculosis in a 60-year-old smoker: A case report. [PDF]

Radiol Case Rep
Azer H, Ganzoui I.
europepmc   +1 more source