Results 171 to 180 of about 49,519 (255)

Implementability of Point‐of‐Care Ultrasound for Paediatric Tuberculosis Diagnosis in Resource‐Constrained Settings: Experiences and Perspectives From Uganda

Tropical Medicine &International Health, EarlyView.
ABSTRACT Introduction Childhood tuberculosis (TB) remains a significant global health challenge, with a substantial number of cases going undiagnosed, particularly among children under five. Early diagnosis and intervention are crucial to reduce TB‐associated morbidity and mortality.
Julia van den Brink, Martien Humblet, Emmanuel Nasinghe, Grace Paul Kisitu, Emmanual Tenywa, Rinn Song, Nora Engel, Francesca Wanda Basile, Else Margreet Bijker   +8 more
wiley   +1 more source

Interinstitutional collaboration to promote public health research in Ecuador: a story of success from the National Institute of Public Health in Ecuador. [PDF]

Front Public Health
Orlando SA, Bruno A, Franco-Sotomayor G, García-Bereguiain MA.   +3 more
europepmc   +1 more source

Patterns of Drug Resistance, Drug Resistance Conferring Mutations and Genomic DNA Methylation Revealed in Mycobacterium tuberculosis From South Africa

Tropical Medicine &International Health, EarlyView.
ABSTRACT Tuberculosis remains a major public health threat globally, with drug‐resistant strains undermining treatment efficacy. We analyzed 126 Mycobacterium tuberculosis (M. tuberculosis) isolates with diverse drug resistance spectra and selected 35 for whole genome sequencing (WGS) using Illumina NextSeq, SMRT PacBio Onso and SMRT PacBio Revio ...
Unarine Matodzi, Awelani Mutshembele, Eric Mensah, Dillon Muzondiwa, Ndivhuho A. Makhado, Oleg N. Reva   +5 more
wiley   +1 more source

Rapid Triage of Smear-Positive Tuberculosis Suspects with a Commercial DNA Microarray: A Real-World Experience from 1100 Sputum Specimens. [PDF]

Infect Drug Resist
Luo C, Zou G, Dai S, Su B, Zhu J, Li K.
europepmc   +1 more source

Histiocytes: Multifaceted Regulators of Health and Disease

Veterinary Clinical Pathology, EarlyView.
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley   +1 more source

Temperature and pH growth preferences predict the pathogenicity and environmental distributions of nontuberculous mycobacteria. [PDF]

mSystems
Gebert MJ, Hasan NA, Pill-Kastens MR, Grant L, Hoffert M, Epperson LE, Strong M, Fierer N.   +7 more
europepmc   +1 more source

Two Years of Ocrelizumab Treatment in Black and Hispanic People with Multiple Sclerosis in CHIMES: A Single‐Arm Clinical Trial

Annals of Neurology, Volume 100, Issue 4, Page 793-807, October 2026.
Objective To evaluate the effectiveness and safety of ocrelizumab in self‐identified black and Hispanic people with relapsing multiple sclerosis. Methods The Characterization of Ocrelizumab in Minorities with Multiple Sclerosis (CHIMES) trial, a prospective, open‐label, single‐arm, phase 4 study, intentionally recruited underrepresented populations in ...
Lilyana Amezcua, Anthony T. Reder, Evanthia Bernitsas, Nancy L. Monson, Timothy Vartanian, Gregory F. Wu, Mansoor Saleh, Annette Okai, Ahmed Z. Obeidat, Dilraj Sokhi, Rikisha Parekh, Jinglan Pei, Christopher Harp, David Clayton, Ibraheem Abioye, Mitzi J. Williams, for the CHIMES Study Group   +16 more
wiley   +1 more source

Editorial: Investigating lung biology, metabolism, and host susceptibility in mycobacterial infections. [PDF]

Front Cell Infect Microbiol
Chandra P, Roth AT, Ronacher K.
europepmc   +1 more source

Novel Pyrazole‐4‐Carbaldehyde Derivatives Having Potent COX‐2 Inhibition and Anti‐Tubercular Activity: Microwave‐Assisted Green Synthesis and Molecular Docking

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 10, October 2026.
ABSTRACT A series of 1‐(4‐Chorophenyl)‐3Aryl‐1‐H‐pyrazole‐4‐carbaldehyde derivatives were synthesized under the microwave irradiation (MW) technique. IR, 1H‐NMR, 13C‐NMR, and mass spectroscopic techniques were used to confirm the structure of the synthesized compounds.
Megha Kokane, Dnyandev Bhosale, Dattatraya Raut, Pushpa Hadimani, Ashwini Narale, Prafulla Choudhari, Anjana Lawand   +6 more
wiley   +1 more source

Comparative evaluation of three commercial real-time PCR kits for direct detection of <i>Mycobacterium tuberculosis</i> complex and non-tuberculous mycobacteria from pulmonary and extrapulmonary clinical samples: experiences from a low-income and high-burden setting. [PDF]

Microbiol Spectr
Rodríguez-Pazmiño ÁS, Carvajal E, Castro-Rodriguez B, Franco-Sotomayor G, Cardenas-Franco G, Uruchima S, Orlando SA, Garcia Bereguiain MA.   +7 more
europepmc   +1 more source