A semiconductor‐fabricated nanowell biosensor enables rapid, scalable, and highly reproducible detection of SARS‐CoV‐2 antigens from nasal swabs within ∼10 minutes. Clinical validation in 249 retrospective and 243 prospective patient samples demonstrates high sensitivity and specificity, minimal cross‐reactivity, and robust batch‐to‐batch ...
Yoo Min Park +11 more
wiley +1 more source
Metabolomics and Artificial Intelligence (AI) assisted metabolomics in the diagnosis of non-tuberculous mycobacterial infections: progress and challenges. [PDF]
Murthy MK, Gupta VK, Maurya AP.
europepmc +1 more source
Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function
This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang +10 more
wiley +1 more source
Metabolism‐Based Biomarkers for Rapid Phenotypic Antibiotic Susceptibility Testing
Metabolic differences emerging after antibiotic exposure provide rapid phenotypic signals of susceptibility and resistance. This review summarizes metabolic biomarkers for rapid phenotypic AST, associated with nutrient uptake, respiratory activity, metabolic reprogramming, and enzymatic function. ABSTRACT The accelerating global crisis of antimicrobial
Sha Yu +7 more
wiley +1 more source
Clinical Characteristics, Molecular Diagnosis, and Drug Resistance Profiles of Nontuberculous Mycobacteria Infections: A Retrospective Analysis Using PCR Melting Curve Technology. [PDF]
Wang K, Xu D, Gao Y, Zhao W, Ma K.
europepmc +1 more source
A hybrid deep learning framework integrating VGG16, ResNet50, and DenseNet121 is proposed for automated tuberculosis detection from chest X‐ray images. Feature‐level fusion enhances robustness and generalization, achieving 97.4% accuracy across multiple public datasets, supporting reliable clinical decision‐making in resource‐limited healthcare ...
Md. Tahmid Hossain +2 more
wiley +1 more source
Non-tuberculous mycobacterial infective endocarditis in a tuberculosis-endemic region after recent cardiovascular procedures: a case series. [PDF]
Arafat SM +5 more
europepmc +1 more source
Intraosseous sarcoidosis imitating peri‐implantitis: A case study
Abstract Background Sarcoidosis is a multisystem granulomatous disorder of unknown cause, typically affecting the lungs and lymph nodes, but it can also involve the eyes, skin, heart, bones, and other organs. The exact cause is unclear, but genetic factors and environmental triggers like infections, chemicals, or dust may play a role.
Magdalena Orlowska +2 more
wiley +1 more source
Analysis of nontuberculous mycobacteria laboratory detection data from a designated hospital in Henan Province, China. [PDF]
Tan J +8 more
europepmc +1 more source

