Results 51 to 60 of about 70,730 (308)

Biosynthesis of mycobacterial arabinogalactan: identification of a novel (13)arabinofuranosyltransferase [PDF]

, 2008
The cell wall mycolyl-arabinogalactan-peptidoglycan complex is essential in mycobacterial species, such as Mycobacterium tuberculosis and is the target of several anti-tubercular drugs.
Alderwick, Luke J., Bai, Yu, Besra, Gurdyal S, Bhatt, Apoorva, Birch, Helen, Eggeling, Lothar, Krumbach, Karin, Lowary, Todd L., Rittmann, Doris, Singh, Albel   +9 more
core   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Comparison of Sputum-Culture Conversion for Mycobacterium bovis and M. tuberculosis

Emerging Infectious Diseases, 2017
Current US guidelines recommend longer treatment for tuberculosis (TB) caused by pyrazinamide-resistant organisms (e.g., Mycobacterium bovis) than for M. tuberculosis TB. We compared treatment response times for patients with M.
Colleen Scott, Joseph S. Cavanaugh, Benjamin J. Silk, Julia Ershova, Gerald H. Mazurek, Philip A. LoBue, Patrick K. Moonan   +6 more
doaj   +1 more source

Mycobacterial panniculitis caused by Mycobacterium thermoresistibile in a cat. [PDF]

, 2016
Case summaryA domestic shorthair cat was evaluated for chronic, bilateral, ulcerative dermatitis affecting the inguinal region and lateral aspects of both pelvic limbs.
Keel, M Kevin, Reagan, Krystle L, Sykes, Jane E, Vishkautsan, Polina   +3 more
core   +2 more sources

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

Gene cooption in Mycobacteria and search for virulence attributes: Comparative proteomic analyses of Mycobacterium tuberculosis, Mycobacterium indicus pranii and other mycobacteria

International Journal of Medical Microbiology, 2014
Tuberculosis (TB), caused by Mycobacterium tuberculosis, is a leading infectious disease taking one human life every 15s globally. Mycobacterium undergoes reductive evolution; the ancestors have bigger genome size and rich in metabolic pathways. Mycobacterium indicus pranii (MIP) is placed much above Mycobacterium tuberculosis (M.tb) in evolutionary ...
Yadvir, Singh, Sakshi, Kohli, Divya Tej, Sowpati, Syed Asad, Rahman, Anil K, Tyagi, Seyed E, Hasnain   +5 more
openaire   +2 more sources

The bacillary and macrophage response to hypoxia in tuberculosis and the consequences for T cell antigen recognition [PDF]

, 2016
M. tuberculosis is a facultative anaerobe and its characteristic pathological hallmark, the granuloma, exhibits hypoxia in humans and in most experimental models. Thus the host and bacillary adaptation to hypoxia is of central importance in understanding
Barry III, CE, Brandenburg, J, Prosser, G, Reiling, N, Wilkinson, KA, Wilkinson, RJ   +5 more
core   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

DNA probes for mycobacteria. I. Isolation of DNA probes for the identification of Mycobacterium tuberculosis complex and for mycobacteria other than tuberculosis (MOTT).

Molecular and cellular probes, 1988
Traditional methods used in identifying mycobacteria such as acid-fast bacillus stains and culture are often time-consuming, insensitive and non-specific. The isolation of DNA probes, coupled to a non-radioactive, e.g. biotin-based detection system, have the potential to foster the development of clinical assays for Mycobacterium tuberculosis and ...
Picken, R. N., Plotch, S. J., Wang, Z., Lin, B. C., Donegan, J. J., Yang, Huey-Lang   +5 more
openaire   +2 more sources

In Vitro Activity of a New Isothiazoloquinolone, ACH-702, against Mycobacterium tuberculosis and Other Mycobacteria [PDF]

Antimicrobial Agents and Chemotherapy, 2010
ABSTRACT In this work, we describe the activity of ACH-702 against clinical isolates of Mycobacterium tuberculosis and six different nontuberculous mycobacteria. The MIC 50 and MIC 90 of both susceptible and drug-resistant M. tuberculosis
Carmen A, Molina-Torres, Jorge, Ocampo-Candiani, Adrian, Rendón, Michael J, Pucci, Lucio, Vera-Cabrera   +4 more
openaire   +2 more sources