Results 111 to 120 of about 408,296 (185)
The tubulin code and its role in controlling microtubule properties and functions
Nature reviews. Molecular cell biology, 2020 C. Janke, M. Magiera
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eLife, 2015 Non-centrosomal microtubule arrays assemble in differentiated tissues to perform mechanical and transport-based functions. In this study, we identify Caenorhabditis elegans NOCA-1 as a protein with homology to vertebrate ninein. NOCA-1 contributes to the
Shaohe Wang +7 more
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γ-Tubulin complexes in microtubule nucleation and beyond
Molecular Biology of the Cell, 2015 Tremendous progress has been made in understanding the functions of γ-tubulin and, in particular, its role in microtubule nucleation since the publication of its discovery in 1989.
B. Oakley, V. Paolillo, Yixian Zheng
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Posttranslational modifications of α-tubulin in alzheimer disease
Translational Neurodegeneration, 2015 In Alzheimer disease (AD), hyperphosphorylation of tau proteins results in microtubule destabilization and cytoskeletal abnormalities. Our prior ultra-morphometric studies documented a clear reduction in microtubules in pyramidal neurons in AD compared ...
Fan Zhang +8 more
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Balancing act: tubulin glutamylation and microtubule dynamics in Toxoplasma gondii [PDF]
The success of Toxoplasma gondii (intracellular parasite) host cell invasion relies on the apical complex, a specialized microtubule cytoskeleton structure associated with secretory organelles.
Basto, Afonso P. +7 more
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Cancer Research, 2015 βIII-tubulin (encoded by TUBB3) expression is associated with therapeutic resistance and aggressive disease in non-small cell lung cancer (NSCLC), but the basis for its pathogenic influence is not understood.
J. McCarroll +12 more
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Surface plasmon resonance study of the actin-myosin sarcomeric complex and tubulin dimers
, 2003 Biosensors based on the principle of surface plasmon resonance (SPR) detection were used to measure biomolecular interactions in sarcomeres and changes of the dielectric constant of tubulin samples with varying concentration.
Alexander A. Kolomenskii +8 more
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Biological Research, 2003 Trypanosoma cruzi epimastigotes were extracted under various conditions in order to examine the role of divalent cations in the solubilization of microtubule proteins.
GRACIELA UZCANGA +3 more
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Biological Research, 2008 HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is characterized by axonal degeneration of the corticospinal tracts. The specific requirements for transport of proteins and organelles to the distal part of the long axon are crucial in
HORACIO MALDONADO +11 more
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Intraflagellar transport delivers tubulin isotypes to sensory cilium middle and distal segments. [PDF]
, 2011 Sensory cilia are assembled and maintained by kinesin-2-dependent intraflagellar transport (IFT). We investigated whether two Caenorhabditis elegans α- and β-tubulin isotypes, identified through mutants that lack their cilium distal segments, are ...
Acar, Seyda +8 more
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