Results 91 to 100 of about 50,722 (204)

Bioengineered Interfaces for Peripheral Nerve Sensory Restoration

Advanced Materials, EarlyView.
Half of amputees abandon their prosthetics for lack of feeling. This review charts the full path from peripheral nerve injury to restored sensation, through surgical, regenerative, noninvasive, and implanted approaches, and shows how injury type and interface material properties determine which strategy can deliver naturalistic feedback, and why ...
Sydney Swedick, Salim El Hadwe, Kesi Liang, George G. Malliaras, Damiano G. Barone   +4 more
wiley   +1 more source

Isolation of functional tubulin dimers and of tubulin-associated proteins from mammalian cells

, 2016
The microtubule (MT) cytoskeleton forms a dynamic filamentous network that is essential for many processes, including mitosis, cell polarity and shape, neurite outgrowth and migration, and ciliogenesis [1, 2]. MTs are built up of α/β-tubulin heterodimers,
Signorile, L., Leslie, K., Ottema, Sophie, Lebbink, J., Lebbink, Joyce, Galjart, N., Smal, I., Ottema, S., Leslie, Kris, Demmers, Jeroen, Yuill, N., Yu, Nuo, Signorile, Luca, Galjart, Niels; id_orcid, Galjart, Niels, Dekkers, D., Smal, Ihor, Basu, S., Basu, Sreya, Demmers, J., Dekkers, Dick   +20 more
core   +1 more source

Synthesis and Characterization of Biocompatible Manganese‐Doped Titania Nanoparticles and Its Application to Single‐Cell Nanoencapsulation

Advanced Materials Interfaces, EarlyView.
Biocompatible Mn‐doped TiO2 nanozymes integrate TiO2 stability with Mn redox activity, enabling dopamine‐mediated cell‐surface polymerization and single‐cell nanoencapsulation while maintaining high colloidal stability, low ROS generation, and excellent cellular compatibility.
Filip Kozłowski, Nayoung Kim, Hyunwoo Choi, Geoffrey Daniel, Gulaim A. Seisenbaeva, Insung S. Choi, Vadim G. Kessler   +6 more
wiley   +1 more source

Resistance to microtubule-stabilising agents following point mutation of human βI-tubulin

, 2015
Marine environments represent a rich source of bioactive secondary metabolites that may be harnessed for use in a therapeutic context. Two novel compounds, peloruside A and laulimalide, isolated from the marine sponges Mycale hentsheli and Cacospongia ...
Rowe, Matthew R., Rowe, Matthew R. (11703470)   +1 more
core   +1 more source

Improved tools for efficient mapping of fission yeast genes:identification of microtubule nucleation modifier mod22-1 as an allele of chromatin- remodelling factor gene swr1 [PDF]

, 2008
Fission yeast genes identified in genetic screens are usually cloned by transformation of mutants with plasmid libraries. However, for some genes this can be difficult, and positional cloning approaches are required.
Sawin, Kenneth E, Watt, Stephen, Bähler, Jürg, Anders, Andreas   +3 more
core   +1 more source

A Whole‐Head Finite Element Model for Electrical Neuromodulation via Visual Brain‐Machine Interfaces

Advanced Science, EarlyView.
A multimodal, personalized head model is presented that integrates the entire visual pathway with surrounding tissues to simulate electrical stimulation of the optic nerve. In vivo validation in humans and goats, plus systematic component‐elimination analysis, demonstrates the high accuracy of the comprehensive model.
Shengjian Lu, Tonghe Yang, Yuan Geng, Huan Wu, Yangrui Huang, Te Zheng, Haodi Chen, Shurui Huang, Yi Cao, Jian Yang, Wentao Yan, Yikui Zhang, Wencan Wu   +12 more
wiley   +1 more source

The performance of anti-tubulin-α-1c antibodies and anti-endothelial cell antibodies in BD diagnosis.

, 2018
The performance of anti-tubulin-α-1c antibodies and anti-endothelial cell antibodies in BD diagnosis.
Cibo Huang (444680), Lei Zhu (16642), Xiaolin Sun (53844), Yuling Chen (438010), Yuhui Li (478816), Haiteng Deng (138991), Zhanguo Li (28423), Yongjing Cheng (444681), Rulin Jia (446574), Xiaozhen Zhao (4579963)   +9 more
core   +1 more source

Taurine is Covalently Incorporated into Alpha Tubulin [PDF]

, 2019
We use various methods of high resolution mass spectrometry to demonstrate that taurine is covalently attached to the carboxyl terminus of alpha Tubulin from avian erythrocytes.
Alfred L, Yergey, Matthew T, Olson, melissa, Pergande, Dan, Sackett, Stephanie, Cologna, susan, Bane, Kamalika, Mukherjee   +6 more
core   +1 more source

A Pentaradial and Bilateral Combined Photoreception System in the Sea Cucumber is Mediated by a Blue Light‐Sensitive R‐Opsin

Advanced Science, EarlyView.
The sea cucumber Holothuria leucospilota detects blue and adjacent wavelengths of light via an r‐opsin with a maximum absorption at 459 nm. In the oral tentacles, papillae, and tube feet, distinct light‐sensing structures with specialized morphologies are formed, constituting a unique pentaradial and bilateral combined photoreception system.
Jiasheng Huang, Chunhua Ren, Zhou Qin, Yimeng Cui, Bingbing Zhang, Peng Luo, Xuan Wang, Yaoqi Xie, Xin Zhang, Aifen Yan, Yang Zhang, Dingding Fan, Yang Liu, Wenjie Pan, Xiao Jiang, Lihong Yuan, Haipeng Qin, David M. Irwin, Chaoqun Hu, Yang Liu, Ting Chen   +20 more
wiley   +1 more source

Modulation of Phosducin-Like Protein 3 (PhLP3) Levels Promotes Cytoskeletal Remodelling in a MAPK and RhoA-Dependent Manner [PDF]

, 2011
Background Phosducin-like protein 3 (PhLP3) forms a ternary complex with the ATP-dependent molecular chaperone CCT and its folding client tubulin. In vitro studies suggest PhLP3 plays an inhibitory role in ?-tubulin folding while conversely in vivo ...
C Mark Smales, Nandini V. L. Hayes, Hayes, Nandini V. L., Hayes Nandini V. L., C. Mark Smales, Carden Martin J., Martin J. Carden, Smales, Christopher Mark, Nandini V L Hayes, Carden, Martin J., Lyne Jossé, Smales C. Mark, Jossé Lyne, Jossé, Lyne, Martin J Carden   +14 more
core   +2 more sources