Results 81 to 90 of about 289,598 (269)
Improved tools for efficient mapping of fission yeast genes:identification of microtubule nucleation modifier mod22-1 as an allele of chromatin- remodelling factor gene swr1 [PDF]
, 2008 Fission yeast genes identified in genetic screens are usually cloned by transformation of mutants with plasmid libraries. However, for some genes this can be difficult, and positional cloning approaches are required.
Sawin, Kenneth E +3 more
core +1 more source
Frontiers in Oncology, 2017 The voltage-dependent anion channel (VDAC) is well known as the pathway for passive diffusion of anionic hydrophilic mitochondrial metabolites across the outer membrane, but a more complex functionality of the three isoforms of VDAC has emerged, as ...
John J. Lemasters, John J. Lemasters
doaj +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Advanced Biology, Volume 9, Issue 3, March 2025.Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
, 2019 Additional file 2: Figure S2. Alterations of mitotic spindle structure, cell cycle progression and apoptosis in SW620 cells. (A) SW620 cells were treated with 80 µM 3,4,4′-TMS for 2 h, fixed and stained with anti-α-tubulin and anti-γ-tubulin antibodies ...
Zulema Percario (6574118) +8 more
core +1 more source
Advanced Functional Materials, EarlyView.An intrinsic photoactive star‐shaped zinc phtalocyanine‐poly(L‐glutamic acid) (ZnPc‐PGA) nanoplatform for multimodal glioblastoma (GBM) therapy and brain‐targeted elivery. A ZnPc‐PGA‐based multifunctional theranostic nanocarrier platform enables image‐guided, multimodal GBM therapy. ZnPc‐PGA nanocarriers support the integration of fluorescence imaging,
Amina Benaicha‐Fernández +14 more
wiley +1 more source
Exploitation of the protein tubulin for controlling African trypanosomiasis
, 2005 This thesis presents the results of an investigation into the structural protein, tubulin, as a potential target for anti-trypanosomatid drug discovery and vaccine development.
Giles, Natalie
core
Tubulin Role in Cancer Development and Treatment [PDF]
, 2019 This review work is done to show a significance of tubulin in cancer development. Within last decades there are a lot of studies have performed in this area.
Dolhyi, V +3 more
core
Template-free 13-protofilament microtubule–MAP assembly visualized at 8 A resolution
, 2010 Microtubule-associated proteins (MAPs) are essential for regulating and organizing cellular microtubules (MTs). However, our mechanistic understanding of MAP function is limited by a lack of detailed structural information. Using cryo-electron microscopy
Houdusse, A. +25 more
core +1 more source
Advanced Functional Materials, EarlyView.A biomimetic hydrogel derived from neonatal spinal cord ECM (DNSCM) delivers LAMB2 protein and ISP peptide to remodel the inhibitory injury microenvironment. The system sustains drug release, upregulates pro‐regenerative LAMB2, downregulates inhibitory CSPG, and promotes axonal regeneration.
Shiyu Fu +8 more
wiley +1 more source
, 1990 Tubulin-G protein interaction: The dynamic role of tubulin in the regulation of the neuronal adenylyl ...
Nan. Wang (7984148)
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