Results 121 to 130 of about 408,296 (185)

Editorial: Cytoskeleton Dynamics as Master Regulator of Organelle Reorganization and Intracellular Signaling for Cell-Cell Competition

Frontiers in Cell and Developmental Biology, 2021
Noa B. Martin-Cofreces, Noa B. Martin-Cofreces, Noa B. Martin-Cofreces, Francisco Sanchez-Madrid, Francisco Sanchez-Madrid, Francisco Sanchez-Madrid, Pedro Roda-Navarro, Pedro Roda-Navarro   +7 more
doaj   +1 more source

Functional genomics identifies five distinct molecular subtypes with clinical relevance and pathways for growth control in epithelial ovarian cancer

EMBO Molecular Medicine, 2013
Epithelial ovarian cancer (EOC) is hallmarked by a high degree of heterogeneity. To address this heterogeneity, a classification scheme was developed based on gene expression patterns of 1538 tumours. Five, biologically distinct subgroups — Epi‐A, Epi‐B,
Tuan Zea Tan, Qing Hao Miow, Ruby Yun‐Ju Huang, Meng Kang Wong, Jieru Ye, Jieying Amelia Lau, Meng Chu Wu, Luqman Hakim Bin Abdul Hadi, Richie Soong, Mahesh Choolani, Ben Davidson, Jahn M. Nesland, Ling‐Zhi Wang, Noriomi Matsumura, Masaki Mandai, Ikuo Konishi, Boon‐Cher Goh, Jeffrey T. Chang, Jean Paul Thiery, Seiichi Mori   +19 more
doaj   +1 more source

In vitro microtubule-nucleating activity of spindle pole bodies in fission yeast Schizosaccharomyces pombe: cell cycle-dependent activation in xenopus cell-free extracts. [PDF]

, 1992
The spindle pole body (SPB) is the equivalent of the centrosome in fission yeast. In vivo it nucleates microtubules (MTs) during mitosis, but, unlike animal centrosomes, does not act as a microtubule organizing center (MTOC) during interphase.
CANDE, W. Zacheus, Masuda, H, Sevik, M
core   +1 more source

Microtubule nucleation by γ-tubulin complexes

Nature reviews. Molecular cell biology, 2011
J. Kollman, A. Merdes, L. Mourey, D. Agard   +3 more
semanticscholar   +1 more source

Single-particle imaging reveals intraflagellar transport–independent transport and accumulation of EB1 in \u3cem\u3eChlamydomonas\u3c/em\u3e flagella [PDF]

, 2016
The microtubule (MT) plus-end tracking protein EB1 is present at the tips of cilia and flagella; end-binding protein 1 (EB1) remains at the tip during flagellar shortening and in the absence of intraflagellar transport (IFT), the predominant protein ...
Harris, J. Aaron, Kner, Peter, Lechtreck, Karl F., Liu, Yi, Yang, Pinfen   +4 more
core   +1 more source

On the Nature and Shape of Tubulin Trails: Implications on Microtubule Self-Organization

, 2012
Microtubules, major elements of the cell skeleton are, most of the time, well organized in vivo, but they can also show self-organizing behaviors in time and/or space in purified solutions in vitro. Theoretical studies and models based on the concepts of
Glade, Nicolas
core   +1 more source

The Centrosome Is a Selective Condensate that Nucleates Microtubules by Concentrating Tubulin

Cell, 2017
Jeffrey B. Woodruff, Beatriz Ferreira Gomes, P. Widlund, J. Mahamid, A. Honigmann, A. Hyman   +5 more
semanticscholar   +1 more source

3D-QSAR, molecular docking, ADMET, simulation dynamic, and retrosynthesis studies on new styrylquinolines derivatives against breast cancer

Open Chemistry
Breast cancer is the most common illness among women, accounting for 25% of all diagnoses, as stated by the American Cancer Society. Current research focuses on 43 compounds of styrylquinoline derivatives as potential inhibitors of tubulin to design a ...
EL-Mernissi Reda, Alaqarbeh Marwa, Khaldan Ayoub, Kara Mohammed, Al kamaly Omkulthom, Alnakhli Anwar M., Lakhlifi Tahar, Sbai Abdelouahid, Ajana Mohammed Aziz, Bouachrine Mohammed   +9 more
doaj   +1 more source

Peptide-mediated display of Tau-derived peptide for construction of microtubule superstructures. [PDF]

RSC Chem Biol
Inaba H, Kageyama D, Watari S, Tateishi M, Kakugo A, Matsuura K.   +5 more
europepmc   +1 more source

The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase.

Molecules and Cells, 2003
Brian J. North, Brett L Marshall, M. Borra, J. Denu, E. Verdin   +4 more
semanticscholar   +1 more source