Results 121 to 130 of about 292,166 (345)

Writing and Reading the Tubulin Code*

Journal of Biological Chemistry, 2015
Microtubules give rise to intracellular structures with diverse morphologies and dynamics that are crucial for cell division, motility, and differentiation.
Ian Yu, C. P. Garnham, A. Roll-Mecak
semanticscholar   +1 more source

The extended tubulin superfamily

Journal of Cell Science, 2001
Although most eukaryotic cells can express multiple isotypes of αβ-tubulin, the significance of this diversity has not always been apparent. Recent data indicate that particular αβ-tubulin isotypes, both genome encoded and those derived by post-translational modification, can directly influence microtubule structure and function — thus validating ideas
McKean, Paul G., Vaughan, Sue, Gull, Keith   +2 more
openaire   +4 more sources

Controlled Magnesium Ion Delivery via Mg‐Sputtered Nerve Conduit for Enhancing Peripheral Nerve Regeneration

Advanced Healthcare Materials, EarlyView.
This study introduces a controllable degradation system for Mg‐based biomaterials using sputtering technology, marking a significant advancement in nerve regeneration research. The Mg‐sputtered nerve conduits demonstrate enhanced biocompatibility, biofunctionality, mechanical compatibility, and precise magnesium release, resulting in improved axonal ...
Hyewon Kim, Jieun Kwon, Hyeok Kim, Sunhee Lee, Seongchan Kim, Ji‐Young Lee, Khandoker Asiqur Rahaman, Taeyeon Kim, Hyojin Lee, Myoung‐Ryul Ok, Seok Chung, Hyung‐Seop Han, Yu‐Chan Kim   +12 more
wiley   +1 more source

α-Tubulin acetylation elevated in metastatic and basal-like breast cancer cells promotes microtentacle formation, adhesion, and invasive migration.

Cancer Research, 2015
Metastatic cases of breast cancer pose the primary challenge in clinical management of this disease, demanding the identification of effective therapeutic strategies that remain wanting.
A. Boggs, M. Vitolo, R. Whipple, Monica S. Charpentier, O. Goloubeva, O. Ioffe, K. Tuttle, Jana Slovic, Yiling Lu, G. Mills, Stuart S. Martin   +10 more
semanticscholar   +1 more source

Impact of Fiber Orientation in Electrospun PLA Scaffolds on Fluid Dynamics in a Custom Microfluidic Device

Advanced Healthcare Materials, EarlyView.
Fiber orientation in electrospun scaffolds affects permeability and fluid dynamics in microfluidic devices. Combining experimental data with computational fluid dynamic simulations, we show that aligned fibers enhance flow uniformity, reduce pressure and shear stress variability.
Elisa Capuana, Maria Testa, Chiara Di Marco, Francesco Lopresti, Vincenzo La Carrubba   +4 more
wiley   +1 more source

Membrane-bound tubulin: fact or artefact? [PDF]

, 1975
Mike Jacobs
openalex   +1 more source

NOCA-1 functions with γ-tubulin and in parallel to Patronin to assemble non-centrosomal microtubule arrays in C. elegans

eLife, 2015
Non-centrosomal microtubule arrays assemble in differentiated tissues to perform mechanical and transport-based functions. In this study, we identify Caenorhabditis elegans NOCA-1 as a protein with homology to vertebrate ninein. NOCA-1 contributes to the
Shaohe Wang, Di Wu, Sophie Quintin, R. Green, Dhanya K. Cheerambathur, Stacy D. Ochoa, A. Desai, K. Oegema   +7 more
semanticscholar   +1 more source

Microphysiological Systems for Comorbidity Studies: Chronic Kidney Disease and Osteoarthritis

Advanced Healthcare Materials, EarlyView.
This review highlights the potential of organ‐on‐a‐chip systems for studying comorbidities, using chronic kidney disease (CKD) and osteoarthritis (OA) as examples. It summarizes recent advances in kidney‐on‐a‐chip and joint‐on‐a‐chip models and discusses their current and potential application in investigating CKD, OA, and CKD‐OA comorbidity, aiming to
Mingying Han, Weiping Lin, Yuanxiong Cao, Patricia Murray, Bettina Wilm, Stephen J McWilliam, Jude Curran, Ruoxiao Xie   +7 more
wiley   +1 more source

Human chromosomes and centrioles as nucleating sites for the in vitro assembly of microtubules from bovine brain tubulin. [PDF]

, 1975
Manley McGill, B. R. Brinkley
openalex   +1 more source

γ-Tubulin complexes in microtubule nucleation and beyond

Molecular Biology of the Cell, 2015
Tremendous progress has been made in understanding the functions of γ-tubulin and, in particular, its role in microtubule nucleation since the publication of its discovery in 1989.
B. Oakley, V. Paolillo, Yixian Zheng
semanticscholar   +1 more source