Results 91 to 100 of about 24,022 (284)

Immunoreactive human chorionic gonadotropin and its free ß-subunit in serum and ascites of patients with malignant tumors [PDF]

, 1992
Human chorionic gonadotropin (hCG) is a clinically relevant marker of trophoblastic and nontrophoblastic malignancies. In the present studies, in addition to determining serum hCG, we investigated the presence and properties of hCG immunoreactivity in ...
Mann, Klaus, Spöttl, Gerald, Jüngst, Dieter, Hörmann, Rudolf, Gerbes, Alexander L.   +4 more
core  

Tobacco Mosaic Virus as a New Carrier for Tumor Associated Carbohydrate Antigens

, 2016
Tumor-associated carbohydrate antigens (TACAs) are being actively studied as targets for antitumor vaccine development. One serious challenge was the low immunogenecity of these antigens.
Philip Bentley (1507624), Sudipa Chowdhury (1507618), Qian Wang (32718), Zhaojun Yin (1507615), Michael A. Bruckman (2054293), Adeline Miermont (2054296), Xuefei Huang (1261959), Jeffrey C. Gildersleeve (462109), Huong Giang Nguyen (2054299)   +8 more
core   +1 more source

Guillain-Barré Syndrome-related campylobacter jejuni in Bangladesh: ganglioside mimicry and cross-reactive antibodies [PDF]

, 2012
BACKGROUND: <br/> Campylobacter jejuni is the predominant antecedent infection in Guillain-Barré syndrome (GBS). Molecular mimicry and cross-reactive immune responses to C.
Klaij, K, Talukder, K.A. (Kaisar), Tio-Gillen, Anne P., Endtz Hubert P., Gilbert Michel, Klaij, K., Jianjun Li (139837), Anne P. Tio-Gillen (139842), Talukder, K.A., Gilbert, Michel, Klaij, Kevin, Kaisar A Talukder, Gillen, Anne, Islam, Zhahirul, Tio-Gillen Anne P., Quazi D Mohammad, Talukder, KA, Talukder, Kaisar A., Gilbert, M., van Rijs, W., Jacobs, Bart C., Alex van Belkum (38419), Hugh J Willison, Islam, Z. (Zhahirul), van Rijs, Wouter, Kevin Klaij, Jacobs Bart C., Willison, H.J. (Hugh), Quazi D. Mohammad (139834), Li, J. (Jianjun), Klaij Kevin, Talukder Kaisar A., Willison, HJ, Mohammad, Quazi D., Gilbert, M. (Michel), Klaij, K. (Kevin), Jacobs, B.C. (Bart), Bart C. Jacobs (139863), Endtz, Hubert, Jianjun Li, Bart C Jacobs, Li, J., Willison, Hugh J., Willison Hugh J., Kevin Klaij (139835), Rijs, Wouter, Zhahirul Islam, Tio-Gillen, A.P., Willison, H.J., Michel Gilbert (60775), Endtz, H.P., van Belkum Alex, Jacobs, B.C., Endtz, Hubert P., Mohammad, QD, van Belkum, Alex, Hugh J. Willison (139850), Mohammad Quazi D., van Rijs Wouter, Hubert P. Endtz (139857), Li, JJ, Michel Gilbert, Kaisar A. Talukder (139846), Mohammad, Q.D., Wouter van Rijs, Mohammad, Q.D. (Quazi), Zhahirul Islam (139833), Belkum, Alex, Hubert P Endtz, Gilbert, M, Belkum, A.F. (Alex) van, Islam Zhahirul, Islam, Z, Islam, Z., Tio-Gillen, A.P. (Anne), Endtz, H.P. (Hubert), Anne P Tio-Gillen, Wouter van Rijs (139839), Rijs, W. (Wouter) van, van Belkum, A., Li, Jianjun, Li Jianjun, Alex van Belkum   +82 more
core   +1 more source

Gut Health in Ostriches (Struthio camelus): Insights Into Intestinal Structure, Functions, Microbiome, and Improvement Strategies

Animal Research and One Health, EarlyView.
Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang, Fang‐Fang Guo, Wen‐Juan Du, Meng Li, Aftab Shaukat, Zhu‐Qing Jia, Shu‐Cheng Huang   +6 more
wiley   +1 more source

MGL‐Based Drug Conjugate: A Novel Glycan‐Targeting Strategy for Potential Precision Cancer Therapy

ChemistryEurope
Cancer remains a major cause of mortality, especially in advanced stages where current therapies are less effective. Antibody‐drug conjugates offer targeted treatment, but their efficacy is limited by on‐target/off‐tumor toxicity since most protein ...
Carlos D. L. Lima, Rafaela Abrantes, Victor Lorrain, Joana Gomes, Reyes Núñez‐Franco, João P. M. António, Catarina Gomes, Ana Gimeno, Benedita A. Pinheiro, Angelina S. Palma, Jesús Jiménez‐Barbero, Pedro M. P. Gois, Gonzalo Jiménez‐Osés, Sandra J. van Vliet, Celso A. Reis, Filipa Marcelo   +15 more
doaj   +1 more source

Improving cellular cancer vaccines

, 2010
Immunization with cancer cells is of great demand in anti-cancer therapy. However, current cellular vaccines are inefficient and there are questions regarding their overall safety. We report a simple and straightforward approach for improving of cellular
Petr Lokhov
core  

Modulation of Animal Gut Health by Milk Oligosaccharide

Animal Research and One Health, EarlyView.
This review summarizes the composition and structural characteristics of MOs across different mammalian species, and elucidates their roles and mechanisms in maintaining intestinal homeostasis by regulating gut microbiome and enhancing intestinal chemical, physical and immune barriers.
Ningtao Chen, Nana Jing, Shiyu Tao, Mingyue Fei, Wentao Lv, Hua Yang, Yingping Xiao, Haiqin Wu   +7 more
wiley   +1 more source

Abstract P6-10-06: Inducing immune responses to tumor associated carbohydrate antigens by a carbohydrate mimetic peptide vaccine: Clinical experience in phase I and phase II trials

, 2017
Active immunization of cancer patients to induce de novo functional anti-tumor immune responses is an alternative/complementary approach to chemotherapy.
LF Hutchins, PD Emanuel, F Jousheghany, T Kieber-Emmons, A Pennisi, BM Karbassi, E Siegel, I Makhoul   +7 more
core   +1 more source

T cells, the Next Big Target in Axial Spondyloarthritis?

Arthritis &Rheumatology, EarlyView.
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease characterized by complex immune dysregulation, with T cells playing a central role in its pathogenesis. In this review, we synthesize current knowledge on diverse T cell subsets in axSpA, their pathogenic mechanisms, and emerging therapeutic strategies targeting these cells. We highlight
Mansi K. Aparnathi, Nigil Haroon
wiley   +1 more source

Pharmacogenomic profiling of the efficacy of gemcitabine monotherapy in metastatic pancreatic cancer: Subgroup analysis of the GENESECT study

British Journal of Clinical Pharmacology, EarlyView.
Aim In the GENESECT study, no significant gemcitabine (GEM) metabolism‐related germline genetic polymorphisms (GPs) were identified because approximately 70% of patients received combination therapy with nab‐paclitaxel, which has metabolic pathways different from GEM.
Takashi Yokokawa, Daiki Tsuji, Masahiro Hatori, Kazuyoshi Kawakami, Masahiko Nakao, Takuya Yano, Yuichiro Arakawa, Keisuke Matsuo, Yasukata Ohashi, Masato Ozaka, Naoki Sasahira, Yasuhiko Sakata, Yuki Kogure, Shinya Tamaki, Atsushi Wada, Yusuke Taki, Wataru Suzuki, Kazuo Kobayashi, Hiroshi Ishii, Kunihiko Itoh, Masakazu Yamaguchi, Kenichi Suzuki   +21 more
wiley   +1 more source