Results 91 to 100 of about 93,268 (298)

Tumor Infiltrating T Lymphocyte and Macrophage Count Associations with Obesity Status reported as median counts (interquartile range) unless otherwise specified.

, 2016
Tumor Infiltrating T Lymphocyte and Macrophage Count Associations with Obesity Status reported as median counts (interquartile range) unless otherwise specified.
Michael Feldman (244700), Charnita Zeigler-Johnson (3143766), Knashawn H. Morales (3143769), Priti Lal (531803)   +3 more
core   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity

Advanced Science, EarlyView.
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu, Xinyu Sun, Wanxia Ma, Jianming Yang, Xuan Sun, Lisong Zhang, Yumeng Liu, Tianshu Ren, Qi Wang, Jingyu Wang, Xiao Li, Xianping Peng, Liu Yang, Junqiang Lv, Zhi Yao, Zhi‐Song Zhang, Quan Wang   +16 more
wiley   +1 more source

Advances in tumor-infiltrating B lymphocytes

Central European Journal of Immunology
In the landscape of tumor immunotherapy, T cell-mediated immune responses have consistently captured the attention, while the contributions of B cells have been neglected. Nevertheless, growing evidence underscores the pivotal role of tumor-infiltrating B cells and plasma cells, collectively termed tumor-infiltrating B lymphocytes (TIL-B), in cancer ...
Zhang, Yule, Huang, Ming, Chen, Jinxiu, Cao, Chunyu, Wu, Hongyan   +4 more
openaire   +3 more sources

CD20+ Tumor Infiltrating B Lymphocyte in Oral Squamous Cell Carcinoma: Correlation with Clinicopathologic Characteristics and Heat Shock Protein 70 Expression

, 2018
Objective. B lymphocyte infiltration in the tumor microenvironment has been proposed to play pivotal roles in tumor progression. Heat shock protein 70 (HSP70) expressed by tumor cells can induce antitumor immune response.
Nasim Taghavi, Alireza Akbarzadeh Baghban, Alireza Arjomandkhah, Zhaleh Mohsenifar   +3 more
core   +1 more source

Non-classic properties of human cytolytic lymphocytes. basic and clinical aspects [PDF]

, 2008
The immune system comprises a complex network of specialized cells and organs that function together to recognize and remove potentially harmful "non-self", i.e. pathogens, malignant cells and –by extension– also transplanted allogeneic cells.
Zenhäusern, Gabriela
core   +1 more source

Pharmacologic Modulation of ARID3A with Rimegepant Reactivates Type I Interferon Signaling and Sensitizes Triple‐Negative Breast Cancer to PD‐1 Blockade

Advanced Science, EarlyView.
This study identifies ARID3A as a key immunosuppressive transcription factor in TNBC. Its inhibition activates the type I IFN pathway, boosting CD8+ T cell infiltration and sensitizing tumors to anti‐PD‐1. The FDA‐approved migraine drug Rimegepant targets ARID3A, enhances immunotherapy efficacy in preclinical models, and establishes a druggable axis to
Teng Zhou, Yifei Zhu, Cheng Zeng, Jinlu Han, Huiying Huang, Doudou Li, Mingxi Lin, Yizi Jin, Qin Guo, Yuxin Yan, Xinhui Mao, Yifei Zhou, Jian Zhang   +12 more
wiley   +1 more source

Dual role of interleukin-2 in tumor-infiltrating lymphocyte therapy

Clinical Cancer Bulletin
Tumor-infiltrating lymphocyte (TIL) therapy has become a promising immunotherapy for the treatment of solid tumors and has shown substantial therapeutic potential in recent years, offering new options for patients with cancer.
Lili Lu, Wenjia Zhuang, Wei Li, Chen Huang, Shuxiu Xiao, Shilong Zhang, Zhou Lu, Jinjin Bai, Zhi Pang, Huajun Jin, Yuhong Zhou, Jianying Gu   +11 more
doaj   +1 more source

Enhancing CAR‐T Cell Efficacy in Solid Tumors by Inhibiting CCL5/VEGF‐Mediated Angiogenesis

Advanced Science, EarlyView.
This study reveals that CAR‐T cells in solid tumors produce CCL5, which paradoxically induces VEGF and angiogenesis to promote tumor growth. Blocking CCL5/VEGF signaling—through gene knockout, or the CCR5 inhibitor maraviroc—significantly enhances the antitumor efficacy of CAR‑T therapy (the diagram was created in Biorender).
Shishuo Sun, Qihong Li, Bixi Wang, Gang Wang, Ying Xue, Yibing Liang, Chenhe Hu, Zhenyu Wang, Xiaoge Gao, Haiheng Xu, Jun Song, Hailong Li, Liantao Li, Xiaoxiao Liu, Patrick Ming‐Kuen Tang, Qing Zhang   +15 more
wiley   +1 more source

Tumor-infiltrating lymphocyte as a prognostic biomarker in stage IV colorectal cancer should take into account the metastatic status and operation modality

, 2018
Qian-Kun Xie,1,* Wen-Zhuo He,1,* Wan-Ming Hu,2–4 Lin Yang,1 Chang Jiang,1 Peng-Fei Kong,1 Yuan-Zhong Yang,2 Qiong Yang,1,5 Hui-Zhong Zhang,2 Bei Zhang,1 Liang-Ping Xia1 1VIP Region, State Key Laboratory of Oncology in South China, Collaborative ...
He WZ, Kong PF, Zhang HZ, Yang L, Hu WM, Xie QK, Jiang C, Xia LP, Yang Q, Zhang B, Yang YZ   +10 more
core