Results 271 to 280 of about 159,317 (346)

A Dynamic Contrast‐Enhanced MRI‐Based Vision Transformer Model for Distinguishing HER2‐Zero, ‐Low, and ‐Positive Expression in Breast Cancer and Exploring Model Interpretability

Advanced Science, EarlyView.
This study develops a Vision Transformer‐based DCE‐MRI model for the non‐invasive classification of HER2 expression in breast cancer, demonstrating robust performance across multicenter cohorts. By integrating transcriptomic analysis, the model reveals immune‐related pathway differences among distinct HER2 expression levels.
Xu Zhang, Yi‐Yuan Shen, Guan‐Hua Su, Yuan Guo, Ren‐Cheng Zheng, Si‐Yao Du, Si‐Yi Chen, Yi Xiao, Zhi‐Ming Shao, Li‐Na Zhang, He Wang, Yi‐Zhou Jiang, Ya‐Jia Gu, Chao You   +13 more
wiley   +1 more source

Tumor-infiltrating lymphocytes in HER2-positive breast cancer: potential impact and challenges. [PDF]

ESMO Open
Schlam I, Loi S, Salgado R, Swain SM.
europepmc   +1 more source

Faculty Opinions recommendation of Programmed cell death 1 ligand 1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancer.

, 2007
Glenn Dranoff
openalex   +2 more sources

In Situ Programming of the Tumor Microenvironment to Alleviate Immunosuppression for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
cmExoaCD11b induced the repolarization of immunosuppressive M2 macrophages into pro‐inflammatory M1 phenotype, thereby promoting the proliferation and activation of CD8+ T cells and reversing the immunosuppressive state of the tumor microenvironment.
Man Sun, Huan Zhang, Yarui Ma, Simiao Wang, Jiayi Chen, Yaxin Cui, Yun Zhang, Siyuan Hu, Dan Zhou, Pengchen Zhang, Yahui Liu, Betty Y.S. Kim, Wen Jiang, Xiaobing Wang, Zhaogang Yang   +14 more
wiley   +1 more source

Tumor-infiltrating lymphocytes in melanoma: from prognostic assessment to therapeutic applications. [PDF]

Front Immunol
Bida M, Miya TV, Hull R, Dlamini Z.
europepmc   +1 more source

An Off‐the‐Shelf Artificial Blood Clot Hydrogel Neutralizing Multiple Proinflammatory Mediators for Pro‐Regenerative Periodontitis Treatment

Advanced Science, EarlyView.
CCS‐RSF@PRP hydrogel is engineered to structurally and functionally mimic the blood clot by integrating PPR, CCS, and RSF nanofibers through in situ activation of PRP. In a rat periodontitis model, CCS‐RSF@PRP hydrogel effectively promotes periodontal tissue repair, attributing to neutralizing the multiple proinflammatory mediators, thus rebuilding a ...
Yini Huangfu, Zhezhe Zhao, Xiang Liu, Jingrong Wang, Yufeng Zhang, Tingting Lan, Yonglan Wang, Chenxuan Wu, Ju Zhang, Pingsheng Huang, Chuangnian Zhang, Anjie Dong, Zujian Feng, Deling Kong, Weiwei Wang   +14 more
wiley   +1 more source

Prediction and analysis of tumor infiltrating lymphocytes across 28 cancers by TILScout using deep learning. [PDF]

NPJ Precis Oncol
Zhang H, Chen L, Li L, Liu Y, Das B, Zhai S, Tan J, Jiang Y, Turco S, Yao Y, Frishman D.   +10 more
europepmc   +1 more source

Bacterial Foreignization Nanosystem Elicits Multi‐Phenotypic T Cells for Antitumor Immunity

Advanced Science, EarlyView.
In this study, a comprehensive strategy for tumor immunogenicity reshaping is implemented, in which all adjuvanticity, antigenicity, and reactogenicity of tumor cells are highly improved by an engineered bacterial nanosystem through a selective membrane fusion process. The resulting foreignized tumor cells evoke potent innate immune responses, inducing
Wan‐Ru Zhuang, Wen‐Chi Xue, Chao Liang, Pan Liu, Yao Lei, Jiaqi He, Ran Cheng, Weidong Nie, Jianxiong Wang, Jie Tang, Hai‐Yan Xie   +10 more
wiley   +1 more source

LGALS3BP antibody-drug conjugate enhances tumor-infiltrating lymphocytes and synergizes with immunotherapy to restrain neuroblastoma growth. [PDF]

J Transl Med
Cela I, Capone E, Pece A, Lovato G, Simeone P, Colasante M, Lamolinara A, Piro A, Iezzi M, Lanuti P, De Laurenzi V, Ippoliti R, Iacobelli S, Sala G.   +13 more
europepmc   +1 more source

Clinical significance of tumor-infiltrating lymphocytes in neoplastic progression and lymph node metastasis of human breast cancer

, 2008
Bor‐Ching Sheu, Wen‐Hung Kuo, Ruey‐Jien Chen, Su‐Cheng Huang, King‐Jen Chang, Song‐Nan Chow   +5 more
openalex   +1 more source