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Tumor-infiltrating Lymphocytes and Prognosis of Hepatocellular Carcinoma
Japanese Journal of Clinical Oncology, 1992Tumor-infiltrating lymphocytes (TIL) were isolated from 17 human hepatocellular carcinomas (HCC). The proliferation of TIL cultured with recombinant interleukin-2 (rIL-2) was evaluated. We also examined prognosis in relation to TIL. Successful expansion of TIL was achieved in 16 of the 17 lesions.
Hiroshi Kobayashi +4 more
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Separation and Characteristics of Tumor-Infiltrating Lymphocytes in Man
1980During the initial phase of tumor immunology, when experiments were conducted with syngeneic systems, without the involvement of reactivities against histocompatibility antigens, the accumulation of important information was explosive. As usual with accumulating knowledge, the number of unanswered questions increased.
M. Fopp +4 more
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Tumor-Infiltrating Lymphocytes and Their Significance in Melanoma Prognosis
2013The role of the tumor-infiltrating lymphocyte (TIL) and its relationship to prognosis has been most extensively studied in malignant melanoma. The purpose of this chapter is to discuss in depth the immunobiology and molecular aspects of lymphocyte function in general and particularly TIL function in the context of antimelanoma immunity.
John F. Thompson +3 more
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Overexpression of caltractin gene in tumor-infiltrating lymphocytes.
International Journal of Oncology, 1998Differential display is a technique which relies on the polymerase chain reaction to identify messenger RNA differences between related tissue samples. We have employed an improved differential display technique, called fluorescent differential display (FDD), to identify the genes that are differentially expressed in normal and malignant mammary ...
Teruyo Sakakura +5 more
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The Prognostic Significance of Tumor-Infiltrating Lymphocytes
2010Tumors have been known to contain variable numbers of lymphocytes, referred to as tumor infiltrating lymphocytes (TILs). The degree of the lymphocytic infiltrate has been shown to correlate with positive outcome in some types of cancers. However, there are conflicting reports regarding the prognosis value of TIL even with the same types of cancers ...
Yang-Xin Fu, Ping Yu
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TUMOR INFILTRATING LYMPHOCYTES*
Annals of the New York Academy of Sciences, 1976Eva Klein +4 more
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Tumor-infiltrating lymphocytes
Critical Reviews in Oncology/Hematology, 1992Theresa L. Whiteside +2 more
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Tumor-Infiltrating Lymphocyte Therapy
The Cancer Journal, 2015Autologous adoptive T-cell therapies have made tremendous strides over the last few years with excitement currently being generated by technologies that can reprogram T-cell specificities toward any desired antigen including chimeric antigen receptors and recombinant T-cell receptors.
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Tumor-Infiltrating Lymphocyte Therapy in Advanced Melanoma
New England Journal of Medicine, 2023Maartje W, Rohaan +2 more
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