Results 71 to 80 of about 337,127 (342)

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Tumor-infiltrating B lymphocytes as an efficient source of highly specific immunoglobulins recognizing tumor cells-7

, 2011
Copyright information:Taken from "Tumor-infiltrating B lymphocytes as an efficient source of highly specific immunoglobulins recognizing tumor cells"http://www.biomedcentral.com/1472-6750/7/70BMC Biotechnology 2007;7():70-70.Published online 18 Oct ...
Daniela Santapaola (59975), Fiorella Petronzelli (58573), Angela Pelliccia (58576), Rita De Santis (58578), Olga Minenkova (5454), Giorgia Monteriù (5445), Valeria D'Alessio (58575), Emiliano Pavoni (5442), Anna Maria Anastasi (58574)   +8 more
core   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Efficacy of Adoptive Therapy with Tumor-infiltrating Lymphocytes and Recombinant Interleukin-2 in Advanced Cutaneous Melanoma: A Systematic Review and Meta-analysis.

Annals of Oncology, 2019
BACKGROUND Adoptive cell therapy (ACT) using autologous tumor-infiltrating lymphocytes (TIL) has been tested in advanced melanoma patients at various centers. We conducted a systematic review and meta-analysis to assess its efficacy on previously treated
U. Dafni, U. Dafni, O. Michielin, S. M. Lluesma, S. M. Lluesma, Z. Tsourti, V. Polydoropoulou, D. Karlis, M. Besser, M. Besser, J. Haanen, I. Svane, Pamela S Ohashi, U. Kammula, A. Orcurto, Stefan Zimmermann, Lionel Trueb, C. A. Klebanoff, C. A. Klebanoff, M. T. Lotze, L. Kandalaft, L. Kandalaft, G. Coukos, G. Coukos   +23 more
semanticscholar   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Tumor-infiltrating B lymphocytes as an efficient source of highly specific immunoglobulins recognizing tumor cells-3

, 2011
Copyright information:Taken from "Tumor-infiltrating B lymphocytes as an efficient source of highly specific immunoglobulins recognizing tumor cells"http://www.biomedcentral.com/1472-6750/7/70BMC Biotechnology 2007;7():70-70.Published online 18 Oct ...
Daniela Santapaola (59975), Fiorella Petronzelli (58573), Angela Pelliccia (58576), Rita De Santis (58578), Olga Minenkova (5454), Giorgia Monteriù (5445), Valeria D'Alessio (58575), Emiliano Pavoni (5442), Anna Maria Anastasi (58574)   +8 more
core   +1 more source

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi, Mohammed Dibas, Patricia Tai, Ala Dibas, Osama Souied, Suhair Al‐Ghabeesh   +5 more
wiley   +1 more source

Generating CAR T cells from tumor-infiltrating lymphocytes

Therapeutic Advances in Vaccines and Immunotherapy, 2021
Background: Tumor-infiltrating lymphocytes (TILs) and chimeric antigen receptor (CAR) T-cell therapies have demonstrated promising, though limited, efficacy against melanoma.
Jane K. Mills, Melissa A. Henderson, Lauren Giuffrida, Pasquale Petrone, Jennifer A. Westwood, Phillip K. Darcy, Paul J. Neeson, Michael H. Kershaw, David E. Gyorki   +8 more
doaj   +1 more source

Tumor-Infiltrating Lymphocytes Help Rein In NSCLC [PDF]

Cancer Discovery, 2020
Abstract In a phase I clinical trial, tumor-infiltrating lymphocyte therapy combined with the anti–PD-1 drug nivolumab was considered safe and tolerable—and exhibited preliminary signs of efficacy—in patients with stage IV or recurrent non–small cell lung cancer.
openaire   +2 more sources

Human Pegivirus Encephalitis With Brain Detection and Response to Sofosbuvir Ledipasvir

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Human pegivirus (HPgV‐1) has been associated with severe encephalomyelitis in immunocompromised patients. Its neurological spectrum remains poorly defined. We report a slowly progressive encephalitis in a person living with well‐controlled HIV, characterized by white matter abnormalities and inflammatory cerebrospinal fluid (CSF). HPgV RNA was
Antoine Moulignier, Françoise Heran, Francis Lallemand, Pierre Bourdillon   +3 more
wiley   +1 more source