Results 31 to 40 of about 135,956 (230)
Research progress and future perspectives of tumor organoid [PDF]
Zhongguo aizheng zazhiTumor organoids, derived from tumor tissues, are three-dimensional structures created in vitro to mimic in vivo tumor growth. They possess comparable genetic lineage and pathological characteristics to the original tumor, making them a promising research
XIAO Yi, WU Ming, YAO Gang
doaj +3 more sources
27 Defining elite macrophages from tumor-on-a-chip
Journal for ImmunoTherapy of Cancer, 2023 Yang Xiang, Xiaohan Feng
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Tumor-on-a-chip for integrating a 3D tumor microenvironment: chemical and mechanical factors. [PDF]
Lab Chip, 2020 Tumor progression is significantly influenced by factors such as mechanical force, shear stress, chemotaxis, and hypoxia. Here, we reviewed recent achievements and presented potential directions for tumor-on-a-chip systems in the future.
Wan L, Neumann CA, LeDuc PR.
europepmc +4 more sources
Applications of Microfluidics and Organ-on-a-Chip in Cancer Research
Biosensors, 2022 Taking the life of nearly 10 million people annually, cancer has become one of the major causes of mortality worldwide and a hot topic for researchers to find innovative approaches to demystify the disease and drug development.
Sagar Regmi +3 more
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Chemotaxis-driven assembly of endothelial barrier in a tumor-on-a-chip platform [PDF]
Lab on a Chip, 2016 Chemotaxis-driven assembly of an endothelial barrier around tumor cells within a microfluidics device.
Aereas, Aung +3 more
openaire +2 more sources
3D Tumor Models and Their Use for the Testing of Immunotherapies
Frontiers in Immunology, 2020 Over the past decade, immunotherapy has become a powerful and evident tool in the fight against cancers. Notably, the rise of checkpoint blockade using monoclonal antibodies (anti-CTLA4, anti-PD1) to avoid interaction between inhibitory molecules allowed
Nicolas Boucherit +2 more
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Advances in analytical microfluidic workflows for differential cancer diagnosis
Nano Select, 2023 Early detection and functional analysis of circulating tumor cells (CTCs) in liquid biopsy rather than counting them offer great promise as physicians can improve differential diagnosis for second‐ or third‐line treatment beyond today's genotype ...
Morteza Hasanzadeh Kafshgari +1 more
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A Tumor-on-a-Chip System with Bioprinted Blood and Lymphatic Vessel Pair. [PDF]
Adv Funct Mater, 2019 AbstractCurrent in vitro antitumor drug screening strategies insufficiently mimic biological systems. They tend to lack true perfusion and draining microcirculation systems, which may post significant limitations in explicitly reproducing the transport kinetics of cancer therapeutics.
Cao X +9 more
europepmc +4 more sources
eLife, 2020 Programmed cell death protein-1 (PD-1) checkpoint immunotherapy efficacy remains unpredictable in glioblastoma (GBM) patients due to the genetic heterogeneity and immunosuppressive tumor microenvironments.
Xin Cui +18 more
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Frontiers in Cell and Developmental Biology, 2021 Pancreatic Ductal Adenocarcinoma (PDAC), the most common pancreatic cancer type, is believed to become the second leading cause of cancer-related deaths by 2030 with mortality rates of up to 93%.
Marlene Geyer, Karla Queiroz
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