Results 61 to 70 of about 1,252,032 (285)

Correlation of tumor budding with a novel and other established prognostic parameters in patients with invasive breast carcinoma

Indian Journal of Pathology and Microbiology
Context: Breast cancer is the most common malignancy among women. Established prognostic markers in breast carcinomas include tumor size, histologic grade, nodal status, lymphovascular invasion, perineural invasion, hormone receptor status, HER-2 status,
Neha D. Borde, Yash M. Thesiya, Meera S. Mahajan, Chandrashekhar P. Bhale   +3 more
doaj   +1 more source

Immunophenotypic profile of tumor buds in breast cancer

Pathology - Research and Practice, 2018
Tumor buds are associated with lympho-vascular invasion and lymph node metastases leading to the assumption that they are involved in the early metastatic process. Hence, it would be important to know if tumor buds can be targeted with the most widely used targeted therapies in breast cancer (BC) and if changes in hormone and Her2 status occur. The aim
Laedrach C, Salhia B, Cihoric N, Zlobec I, Tapia C   +4 more
openaire   +3 more sources

From Cell‐Derived Vesicles to Hybrid Nanovectors: Biological Membranes as Functional Blueprints for Gene Delivery

Advanced Healthcare Materials, EarlyView.
Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari, Claudia Leone, Gabriella Leccese, Claudia De Stradis, Alessandra Invidia, Concetta Quintarelli, Biagio De Angelis, Franco Locatelli, Giuseppe Gigli, Gabriele Maiorano, Ilaria Elena Palamà   +10 more
wiley   +1 more source

Joint Tumor Bud–MMP/TIMP Count at the Invasive Front Improves the Prognostic Evaluation of Invasive Breast Carcinoma

Biomedicines, 2021
Background: Tumor budding is a histological phenomenon consisting of the formation of small clusters of one to five undifferentiated malignant cells detached from the main tumor mass which are observed in the tumor stroma.
Luis O. González, Noemi Eiro, María Fraile, Rosario Sánchez, Alejandro Andicoechea, Silvia Fernández-Francos, Jose Schneider, Francisco J. Vizoso   +7 more
doaj   +1 more source

Tumor Budding in Oral Squamous Cell Carcinoma

The Journal of Contemporary Dental Practice, 2017
How to cite this article Sarode GS, Sarode SC, Deshmukh R, Anand R, Patil S. Tumor Budding in Oral Squamous Cell Carcinoma. J Contemp Dent Pract 2017;18(9):743-744.
Gargi S, Sarode, Sachin C, Sarode, Revati, Deshmukh, Rahul, Anand, Shankargouda, Patil   +4 more
openaire   +2 more sources

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Functional Suppression of SCAP Triggers Endoplasmic Reticulum Stress‐Dependent Ferroptosis by Impairing Cholesterol Metabolism in Gastric Cancer

Advanced Science, EarlyView.
This study reveals a novel GC therapy targeting cholesterol homeostasis. Inhibiting the SCAP sterol‐sensing domain causes lethal ER stress via cholesterol accumulation, paradoxically forcing continuous synthesis that triggers ferroptosis. The findings link sterol sensing, metabolic dysregulation, and ferroptosis, establishing an anti‐cancer paradigm ...
Qianqian Xu, Guangzhao Pan, Lele Zhang, Xiangliu Chen, Kui Zhang, Yang Lu, Zibo Duan, Aiping Chen, Hailong Shen, Yuxi Zhang, Xiaowu Dong, Jinzhou Huang, Xing Huang, Kai Miao, Qian Hua, Fangfang Tao, Weidong Zhang, Jiang‐Jiang Qin   +17 more
wiley   +1 more source

Tumor Budding as an Independent Prognostic Histopathological Marker in Oral Squamous Cell Carcinoma - An Indian Tertiary Care Center Experience [PDF]

Türk Patoloji Dergisi
Objective: Oral squamous cell carcinoma is the most common head and neck malignancy reported worldwide. Tumor budding represents a histopathological feature characterized by the presence of isolated single/small clusters of cancer cells dispersed within ...
Anand Vijaya NARAYANAN, Krishnapriya UMASHANKAR, Sithara ARAVIND, Sangeetha. K. NAYANAR, Sandeep VIJAY   +4 more
doaj   +1 more source

Expression of the hyaluronan-mediated motility receptor RHAMM in tumor budding cells identifies aggressive colorectal cancers. [PDF]

, 2015
Expression of the hyaluronan-mediated motility receptor (RHAMM, CD168) predicts adverse clinicopathological features and decreased survival for colorectal cancer (CRC) patients. Using full tissue sections, we investigated the expression of RHAMM in tumor
Trippel, Mafalda, Kölzer, Viktor, Koelzer, Viktor H., Karamitopoulou, Eva, Lugli, Alessandro, Zlobec, Inti, Huber, Bettina, Mele, Valentina, Karamitopoulou, Evanthia, Iezzi, Giandomenica   +9 more
core   +1 more source

Relationship between Tumor Budding and Partial Epithelial–Mesenchymal Transition in Head and Neck Cancer

, 2023
Tumor budding (TB), a microscopic finding in the stroma ahead of the invasive fronts of tumors, has been well investigated and reported as a prognostic marker in head and neck squamous cell carcinoma (HNSCC). Epithelial–mesenchymal transition (EMT)
Souichi Yanamoto, Kohei Okuyama, Keiji Suzuki   +2 more
core   +1 more source