Results 51 to 60 of about 1,252,032 (285)

Significance of tumor budding in colorectal carcinoma – A tertiary care center study

Asian Journal of Medical Sciences, 2022
Background: Colorectal carcinoma is one of the leading causes of mortality worldwide. Although the current TNM staging helps in prognostic stratification, these cancers are known to show heterogeneous behavior within the same stage.
Preeta Naik , Hemalatha J , Sowmya T S , Nagesha K R   +3 more
doaj   +1 more source

High tumor budding activity may predict poor prognosis in laryngeal squamous cell carcinomas

Indian Journal of Pathology and Microbiology, 2022
Background: Laryngeal squamous cell carcinoma (SCC) which is the most common carcinoma of the respiratory system after lung carcinomas is graded by the World Health Organization (WHO) into three groups as grades 1, 2, and 3.
Çiğdem öztürk, Hüsniye Esra Paşaoğlu, Funda Emre, Tülin Şentürk Ege, Ümit Seza Tetikkurt   +4 more
doaj   +1 more source

Use of a Combination of CEA and Tumor Budding to Identify High-risk Patients with Stage II Colon Cancer

The International Journal of Biological Markers, 2017
Background High-risk patients with stage II colon cancer may benefit from adjuvant chemotherapy, but identifying this patient population can be difficult.
Changzheng Du, Weicheng Xue, Fangyuan Dou, Yifan Peng, Yunfeng Yao, Jun Zhao, Jin Gu MD, FACS   +6 more
doaj   +1 more source

Tumor budding correlates with tumor invasiveness and predicts worse survival in pT1 non-muscle-invasive bladder cancer

Scientific Reports, 2021
Tumor budding is defined as a single cell or a cluster of up to 5 tumor cells at the invasion front. Due to the difficulty of identifying patients at high risk for pT1 non-muscle-invasive bladder cancer (NMIBC) and the difficulties in T1 substaging ...
Markus Eckstein, Charlotte Kimmel, Johannes Bruendl, Florian Weber, Stefan Denzinger, Michael Gierth, Maximilian Burger, Arndt Hartmann, Wolfgang Otto, Johannes Breyer   +9 more
doaj   +1 more source

Tumor budding in cervical carcinoma: Associations with some clinical and pathological factors [PDF]

Archive of Oncology, 2021
Background: Tumor budding is recognized as an important independent prognostic factor in colorectal carcinoma. The aim of this study was to evaluate the grade of tumor budding and association with other clinical and pathological features in patients with
Stanulović Nevena, Ivković-Kapicl Tatjana, Mandić Aljoša, Gutić Bojana   +3 more
doaj  

Active immunosurveillance in the tumor microenvironment of colorectal cancer is associated with low frequency tumor budding and improved outcome. [PDF]

, 2015
Tumor budding (single tumor cells or small tumor cell clusters) at the invasion front of colorectal cancer (CRC) is an adverse prognostic indicator linked to epithelial-mesenchymal transition.
Andersson, E, Koelzer, VH, Kölzer, Viktor, Masucci, Giuseppe V, Zlobec, Inti, Alessandro Lugli, Lugli, A, Karamitopoulou, E, Andersson, Emilia, Zlobec, I, Karamitopoulou, Evanthia, Giuseppe V. Masucci, Heather Dawson, Inti Zlobec, Dawson, H, Masucci, GV, Eva Karamitopoulou, Emilia Andersson, Lugli, Alessandro, Dawson, Heather, Viktor H. Koelzer   +20 more
core   +1 more source

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

Advanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz, Manuel P. Kainz, Niklas Haider, Theresa Rienmüller, Kerstin Lenk, Rupert Kargl, Michele Terzano, Gerhard Sommer, Gerhard A. Holzapfel, Julia Fuchs   +9 more
wiley   +1 more source

Establishment and Clinical Application of an Artificial Intelligence Diagnostic Platform for Identifying Rectal Cancer Tumor Budding

Frontiers in Oncology, 2021
Tumor budding is considered a sign of cancer cell activity and the first step of tumor metastasis. This study aimed to establish an automatic diagnostic platform for rectal cancer budding pathology by training a Faster region-based convolutional neural ...
Shanglong Liu, Yuejuan Zhang, Yiheng Ju, Ying Li, Xiaoning Kang, Xiaojuan Yang, Tianye Niu, Xiaoming Xing, Yun Lu   +8 more
doaj   +1 more source

Immunohistochemical analysis of tumor budding in stage II colon cancer: exploring zero budding as a prognostic marker. [PDF]

Tumor budding, a biomarker traditionally evaluated using hematoxylin and eosin (H&E) staining, has gained recognition as a prognostic biomarker for stage II colon cancer.
Timm, Signe, Korsgaard, Ulrik, Zlobec, Inti, Pihlmann Kristensen, Maria, Frøstrup Hansen, Torben, Hager, Henrik, Frøstrup Hansen, Torben; id_orcid, Kjær-Frifeldt, Sanne   +7 more
core   +2 more sources

How is Nanoarchitectonics Shaping Extracellular Vesicle Research?

Advanced Healthcare Materials, EarlyView.
The convergence of nanoarchitectonics and extracellular vesicle biology is reshaping next‐generation nanomedicine by enabling rationally designed nanostructures for enhanced EVs detection, engineering, and therapy. ABSTRACT Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell‐to‐cell communication, holding immense potential
Madushani Dahanayake, Md Shahriar A. Hossain, Chia‐Hung Liu, Carlos Salomon, Yusuke Yamauchi, Mostafa Kamal Masud   +5 more
wiley   +1 more source