Results 11 to 20 of about 2,314,582 (300)

The action of ionizing irradiation alone or in combination with cisplatin on malignant cells: Investigations in vitro [PDF]

Archive of Oncology, 2003
The paper gives a brief review of the literature data based on in vitro investigations of cytotoxic action of cisplatin and irradiation, applied alone or in combination, to carcinoma cell lines and fresh tumor explants.
Juranić Zorica D., Čolaković Slobodanka, Sarić Milan, Čikarić Slobodan   +3 more
doaj   +1 more source

Lymphocytes in tumor-draining lymph nodes co-cultured with autologous tumor cells for adoptive cell therapy

Journal of Translational Medicine, 2022
Background Tumor-draining lymph nodes (TDLNs) are primary sites, where anti-tumor lymphocytes are primed to tumor-specific antigens and play pivotal roles in immune responses against tumors. Although adoptive cell therapy (ACT) using lymphocytes isolated
Kazumi Okamura, Satoshi Nagayama, Tomohiro Tate, Hiu Ting Chan, Kazuma Kiyotani, Yusuke Nakamura   +5 more
doaj   +1 more source

Photodynamic Efficacy of Cercosporin in 3D Tumor Cell Cultures [PDF]

Photochemistry and Photobiology, 2020
AbstractIn the present work, we study the photodynamic action of cercosporin (cerco), a naturally occurring photosensitizer, on human cancer multicellular spheroids. U87 spheroids exhibit double the uptake of cerco than T47D and T98G spheroids as shown by flow cytometry on the single cell level.
Theodossis A. Theodossiou, Mathilde Ménard, Maria Mastrangelopoulou, Ellen Skarpen, Kristian Berg, Asta Juzeniene, Mantas Grigalavicius, Delmon Arous, Delmon Arous   +8 more
openaire   +5 more sources

[Impact of neutron radiation on the viability of tumor cells cultured in the presence of boron-10 isotope].

Journal of radiology and nuclear medicine, 2016
Objective To investigate the impact of a neutron beam formed with the accelerator-based epithermal neutron source designed at the G.I. Budker Institute of Nuclear Physics (INP) on the viability of human and animal tumor cells cultured in the presence of ...
O. Volkova, L. Mechetina, A. Taranin, A. Zaboronok, K. Nakai, S. Lezhnin, S. Frolov, D. Kasatov, A. Makarov, I. Sorokin, T. Sycheva, I. Shchudlo, S. Taskaev   +12 more
semanticscholar   +1 more source

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha

Journal of Experimental Medicine, 1994
Using granulocyte/macrophage colony-stimulating factor (GM-CSF) and interleukin 4 we have established dendritic cell (DC) lines from blood mononuclear cells that maintain the antigen capturing and processing capacity characteristic of immature dendritic ...
F. Sallusto, A. Lanzavecchia
semanticscholar   +1 more source

Culture of Zollinger-Ellison Tumor Cells

Gastroenterology, 1975
We have successfully grown six Zollinger-Ellison tumors in vitro with use of a monlayer tissue culture technique. The initial gastrin concentration in the medium varied between 0 and 100 ng per ml. Many cytoplasmic secretory granules were seen in the cells of one culture population.
Edward Passaro, Graham J. Dockray, Lenard M. Lichtenberger, Juan Lechago   +3 more
openaire   +3 more sources

CAFs affect the proliferation and treatment response of head and neck cancer spheroids during co-culturing in a unique in vitro model

Cancer Cell International, 2020
Background Head and neck squamous cell carcinoma (HNSCC) is a heterogeneous group of tumors for which the overall survival rate worldwide is around 60%. The tumor microenvironment, including cancer-associated fibroblasts (CAFs), is believed to affect the
Mustafa Magan, Emilia Wiechec, Karin Roberg   +2 more
doaj   +1 more source

Development of an acellular tumor extracellular matrix as a three-dimensional scaffold for tumor engineering. [PDF]

PLoS ONE, 2014
Tumor engineering is defined as the construction of three-dimensional (3D) tumors in vitro with tissue engineering approaches. The present 3D scaffolds for tumor engineering have several limitations in terms of structure and function.
Wei-Dong Lü, Lei Zhang, Chun-Lin Wu, Zhi-Gang Liu, Guang-Yan Lei, Jia Liu, Wei Gao, Ye-Rong Hu   +7 more
doaj   +1 more source

Morphological Differences between Circulating Tumor Cells from Prostate Cancer Patients and Cultured Prostate Cancer Cells

PLoS ONE, 2014
Circulating tumor cell (CTC) enumeration promises to be an important predictor of clinical outcome for a range of cancers. Established CTC enumeration methods primarily rely on affinity capture of cell surface antigens, and have been criticized for ...
Sunyoung Park, Richard R Ang, S. Duffy, J. Bazov, K. Chi, P. Black, Hongshen Ma   +6 more
semanticscholar   +1 more source

Culture and application of conditionally reprogrammed primary tumor cells [PDF]

Gastroenterology Report, 2020
AbstractCancer is still a major public-health problem that threatens human life worldwide and further study needs to be carried out in the basic and preclinical areas. Although high-throughput sequencing technology and individualized precise therapy have made breakthroughs over the years, the high failure rate of clinical translational research has ...
Liwu Fu, Mengjun Zhong
openaire   +3 more sources