Results 11 to 20 of about 2,710,879 (342)
DBCCR1 mediates death in cultured bladder tumor cells [PDF]
Oncogene, 2004 Chromosome 9, which is often partially or fully reduced to homozygosity in bladder cancer cells, harbors several tumor suppressor loci including deleted in bladder cancer chromosome region 1 (DBCCR1) at 9q32-33. To study DBCCR1 function, stable cell lines, inducible for DBCCR1 expression by tetracycline, were made, but the DBCCR1 protein was not ...
Kate O, Wright +2 more
openaire +3 more sources
Silencing of TGF-β1 in tumor cells impacts MMP-9 in tumor microenvironment
Scientific Reports, 2017 Transforming growth factor (TGF)-β1 contributes to autocrine and paracrine functions in the tumor microenvironment (TME). The present study examined the effects of TGF-β1 crosstalk in TME and its role in mediating tumor formation and progression by ...
Lakisha D. Moore-Smith +4 more
doaj +2 more sources
Journal of Translational Medicine, 2022 Background Tumor-draining lymph nodes (TDLNs) are primary sites, where anti-tumor lymphocytes are primed to tumor-specific antigens and play pivotal roles in immune responses against tumors. Although adoptive cell therapy (ACT) using lymphocytes isolated
Kazumi Okamura +5 more
doaj +1 more source
Journal of radiology and nuclear medicine, 2016 Objective To investigate the impact of a neutron beam formed with the accelerator-based epithermal neutron source designed at the G.I. Budker Institute of Nuclear Physics (INP) on the viability of human and animal tumor cells cultured in the presence of ...
O. Volkova +12 more
semanticscholar +1 more source
Tumor-induced senescent T cells promote the secretion of pro-inflammatory cytokines and angiogenic factors by human monocytes/macrophages through a mechanism that involves Tim-3 and CD40L [PDF]
, 2014 Solid tumors are infiltrated by immune cells where macrophages and senescent T cells are highly represented. Within the tumor microenvironment, a cross-talk between the infiltrating cells may occur conditioning the characteristic of the in situ immune ...
Acosta Rodriguez, Eva Virginia +8 more
core +2 more sources
Journal of Experimental Medicine, 1994 Using granulocyte/macrophage colony-stimulating factor (GM-CSF) and interleukin 4 we have established dendritic cell (DC) lines from blood mononuclear cells that maintain the antigen capturing and processing capacity characteristic of immature dendritic ...
F. Sallusto, A. Lanzavecchia
semanticscholar +1 more source
Cancer Cell International, 2020 Background Head and neck squamous cell carcinoma (HNSCC) is a heterogeneous group of tumors for which the overall survival rate worldwide is around 60%. The tumor microenvironment, including cancer-associated fibroblasts (CAFs), is believed to affect the
Mustafa Magan +2 more
doaj +1 more source
Development of an acellular tumor extracellular matrix as a three-dimensional scaffold for tumor engineering. [PDF]
PLoS ONE, 2014 Tumor engineering is defined as the construction of three-dimensional (3D) tumors in vitro with tissue engineering approaches. The present 3D scaffolds for tumor engineering have several limitations in terms of structure and function.
Wei-Dong Lü +7 more
doaj +1 more source
Culture of Zollinger-Ellison Tumor Cells
Gastroenterology, 1975 We have successfully grown six Zollinger-Ellison tumors in vitro with use of a monlayer tissue culture technique. The initial gastrin concentration in the medium varied between 0 and 100 ng per ml. Many cytoplasmic secretory granules were seen in the cells of one culture population.
L M, Lichtenberger +3 more
openaire +2 more sources
Tumor-reactive immune cells protect against metastatic tumor and induce immunoediting of indolent but not quiescent tumor cells [PDF]
, 2016 Two major barriers to cancer immunotherapy include tumor-induced immune suppression mediated by myeloid-derived suppressor cells and poor immunogenicity of the tumor-expressing self-antigens.
Bear, Harry D. +8 more
core +2 more sources