Photodynamic Efficacy of Cercosporin in 3D Tumor Cell Cultures [PDF]
Photochemistry and Photobiology, 2020 AbstractIn the present work, we study the photodynamic action of cercosporin (cerco), a naturally occurring photosensitizer, on human cancer multicellular spheroids. U87 spheroids exhibit double the uptake of cerco than T47D and T98G spheroids as shown by flow cytometry on the single cell level.
Grigalavicius, Mantas +7 more
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Advances in Radiation Oncology, 2021 Purpose: Preclinical and clinical data indicate that radiation therapy acts as an immune modifier, having both immune-stimulatory and immunosuppressive effects on the tumor-immune microenvironment (TIME).
Lijun Li, MD +5 more
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Resistance to cytotoxicity and sustained release of interleukin-6 and interleukin-8 in the presence of decreased interferon-γ after differentiation of glioblastoma by human natural killer cells. [PDF]
, 2016 Natural killer (NK) cells are functionally suppressed in the glioblastoma multiforme (GBM) tumor microenvironment. We have recently shown that survival and differentiation of cancer stem-like cells (CSCs)/poorly differentiated tumors are controlled ...
Bui, Vickie T +8 more
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Tissue culture of human thyroid cancer [PDF]
, 1968 Human thyroid cancer cells in the pleural effusion were serially cultivated in vitro. Three kinds of cell lines were established from the same primary culture and were designated as PS, TS and TR lines, respectively.
Hirose, Masaharu
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The action of ionizing irradiation alone or in combination with cisplatin on malignant cells: Investigations in vitro [PDF]
Archive of Oncology, 2003 The paper gives a brief review of the literature data based on in vitro investigations of cytotoxic action of cisplatin and irradiation, applied alone or in combination, to carcinoma cell lines and fresh tumor explants.
Juranić Zorica D. +3 more
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A cell line derived from BBN (N-butyl-N-[4-hydroxybutyl]-nitrosamine)-induced rat bladder cancer: establishment and scanning electron microscopic cell surface characteristics [PDF]
, 1978 This research was performed to establish a cell line from experimental bladder tumor and to discuss the biological characteristics of the cell line so established. Tissue cultures of epithelial cells were derived from a rat bladder cancer induced by BBN.
Nishi, Mitsuo
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Frontiers in Immunology, 2021 Cancer-associated fibroblasts (CAFs) has been recognized as one cause of tumor resistance to immune checkpoint blockade therapy, but the underlying mechanisms still remain elusive.
Tinglei Huang +9 more
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Protective effect of stromal Dickkopf-3 in prostate cancer: opposing roles for TGFBI and ECM-1 [PDF]
, 2018 Aberrant transforming growth factor–β (TGF-β) signaling is a hallmark of the stromal microenvironment in cancer. Dickkopf-3 (Dkk-3), shown to inhibit TGF-β signaling, is downregulated in prostate cancer and upregulated in the stroma in benign prostatic ...
A Dutta +65 more
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Macrophage induces anti-cancer drug resistance in canine mammary gland tumor spheroid
Scientific Reports, 2023 Tumor-associated macrophages (TAMs) play an important role in the tumor microenvironment by producing cytokines and growth factors. Furthermore, TAMs play multifunctional roles in tumor progression, immune regulation, metastasis, angiogenesis, and ...
Ga-Hyun Lim +6 more
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Frontiers in Oncology, 2022 BackgroundEvidence has shown neurons and glial cells were closely related to tumor progression. As the predominant glial cells in the external innervated nerves of the gastrointestinal, the role of Schwann cells (SCs) in colorectal cancer (CRC) has not ...
Shuhai Chen, Mingyou Chen
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