Results 21 to 30 of about 651,598 (267)
Versican modulates tumor-associated macrophage properties to stimulate mesothelioma growth
OncoImmunology, 2019 Versican promotes experimental tumor growth through cell- and non cell-autonomous mechanisms. Its role in mesothelioma progression has not been investigated so far.
Apostolos G. Pappas +8 more
doaj +1 more source
Effect of IL-10-producing B cells in peripheral blood and tumor tissue on gastric cancer
Cell Communication and Signaling, 2023 Background Interleukin (IL)-10-producing B (B10) cells are generated in response to signals from the tumor microenvironment and promote tumor growth by interacting with B10 cells.
Yoon Ju Jung +9 more
doaj +1 more source
Human macrophage-engineered vesicles for utilization in ovarian cancer treatment
Frontiers in Oncology, 2023 BackgroundOvarian cancer is a deadly female malignancy with a high rate of recurrent and chemotherapy-resistant disease. Tumor-associated macrophages (TAMs) are a significant component of the tumor microenvironment and include high levels of M2-protumor ...
David Schweer +12 more
doaj +1 more source
Effect of Podophyllin on Tumor Cells in Tissue Culture.
Experimental Biology and Medicine, 1947 Conclusions1. Podophyllin exerts a selective damaging effect on mouse tumor cells in tissue culture over the concentration range 0.08-20.0 mg/1. 2. This damaging effect is more easilv reversible in normal than in tumor cells. 3. Podophyllotoxin is not as effective as podophyllin in causing selective tumor damage. 4.
R A, ORMSBEE, I, CORNMAN, R E, BERGER
openaire +2 more sources
Brazilian Journal of Medical and Biological Research, 1998 Macrophages are important components of natural immunity involved in inhibition of tumor growth and destruction of tumor cells. It is known that these cells can be activated for tumoricidal activity by lymphokines and bacterial products.
F. Ribeiro-Dias +5 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
BMC Cancer, 2005 Background The purpose of this study was to test the hypothesis that mast cells that are present in fibrotic regions of cancer can suppress the growth of tumor cells through an indirect mechanism involving peri-tumoral fibroblasts.
Kanakubo Emi +2 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
AIP Advances, 2019 Understanding the mechanisms of cancer development and metastasis requires comprehensive analyses of interactions between normal and tumor cells and the extracellular matrix (ECM) in hypoxic tumor microenvironments.
Daisuke Yoshino, Kenichi Funamoto
doaj +1 more source
M2 macrophage inhibits the antitumor effects of Lenvatinib on intrahepatic cholangiocarcinoma
Frontiers in Immunology, 2023 Background and objectivesThe relationship between the tumor microenvironment and the network of key signaling pathways in cancer plays a key role in the occurrence and development of tumors.
Long Yang +11 more
doaj +1 more source