Results 11 to 20 of about 651,598 (267)

CAFs affect the proliferation and treatment response of head and neck cancer spheroids during co-culturing in a unique in vitro model

open access: yesCancer Cell International, 2020
Background Head and neck squamous cell carcinoma (HNSCC) is a heterogeneous group of tumors for which the overall survival rate worldwide is around 60%. The tumor microenvironment, including cancer-associated fibroblasts (CAFs), is believed to affect the
Mustafa Magan   +2 more
doaj   +1 more source

Culture of Zollinger-Ellison Tumor Cells

open access: yesGastroenterology, 1975
We have successfully grown six Zollinger-Ellison tumors in vitro with use of a monlayer tissue culture technique. The initial gastrin concentration in the medium varied between 0 and 100 ng per ml. Many cytoplasmic secretory granules were seen in the cells of one culture population.
L M, Lichtenberger   +3 more
openaire   +2 more sources

Photodynamic Efficacy of Cercosporin in 3D Tumor Cell Cultures [PDF]

open access: yesPhotochemistry and Photobiology, 2020
AbstractIn the present work, we study the photodynamic action of cercosporin (cerco), a naturally occurring photosensitizer, on human cancer multicellular spheroids. U87 spheroids exhibit double the uptake of cerco than T47D and T98G spheroids as shown by flow cytometry on the single cell level.
Grigalavicius, Mantas   +7 more
openaire   +4 more sources

Development of an acellular tumor extracellular matrix as a three-dimensional scaffold for tumor engineering. [PDF]

open access: yesPLoS ONE, 2014
Tumor engineering is defined as the construction of three-dimensional (3D) tumors in vitro with tissue engineering approaches. The present 3D scaffolds for tumor engineering have several limitations in terms of structure and function.
Wei-Dong Lü   +7 more
doaj   +1 more source

3,3'-Diindolylmethane Enhances Tumor Regression After Radiation Through Protecting Normal Cells to Modulate Antitumor Immunity

open access: yesAdvances in Radiation Oncology, 2021
Purpose: Preclinical and clinical data indicate that radiation therapy acts as an immune modifier, having both immune-stimulatory and immunosuppressive effects on the tumor-immune microenvironment (TIME).
Lijun Li, MD   +5 more
doaj   +1 more source

The action of ionizing irradiation alone or in combination with cisplatin on malignant cells: Investigations in vitro [PDF]

open access: yesArchive of Oncology, 2003
The paper gives a brief review of the literature data based on in vitro investigations of cytotoxic action of cisplatin and irradiation, applied alone or in combination, to carcinoma cell lines and fresh tumor explants.
Juranić Zorica D.   +3 more
doaj   +1 more source

Wnt Inhibition Sensitizes PD-L1 Blockade Therapy by Overcoming Bone Marrow-Derived Myofibroblasts-Mediated Immune Resistance in Tumors

open access: yesFrontiers in Immunology, 2021
Cancer-associated fibroblasts (CAFs) has been recognized as one cause of tumor resistance to immune checkpoint blockade therapy, but the underlying mechanisms still remain elusive.
Tinglei Huang   +9 more
doaj   +1 more source

Isolation of Tumor Cell Colonies in Tissue Culture.

open access: yesExperimental Biology and Medicine, 1958
SummaryA procedure is described for isolation of colonies of mammalian cells in tissue culture. Cell lines of a mouse ependymoma obtained in this way differed in growth characteristics, in capacity to grow, in vivo, and in susceptibility to Theiler's GDVII virus.
H E, PEARSON, D L, LAGERBORG
openaire   +2 more sources

Macrophage induces anti-cancer drug resistance in canine mammary gland tumor spheroid

open access: yesScientific Reports, 2023
Tumor-associated macrophages (TAMs) play an important role in the tumor microenvironment by producing cytokines and growth factors. Furthermore, TAMs play multifunctional roles in tumor progression, immune regulation, metastasis, angiogenesis, and ...
Ga-Hyun Lim   +6 more
doaj   +1 more source

Schwann cells promote the migration and invasion of colorectal cancer cells via the activated NF-κB/IL-8 axis in the tumor microenvironment

open access: yesFrontiers in Oncology, 2022
BackgroundEvidence has shown neurons and glial cells were closely related to tumor progression. As the predominant glial cells in the external innervated nerves of the gastrointestinal, the role of Schwann cells (SCs) in colorectal cancer (CRC) has not ...
Shuhai Chen, Mingyou Chen
doaj   +1 more source

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