Results 11 to 20 of about 913,938 (308)

Assessing Various Control Samples for Microarray Gene Expression Profiling of Laryngeal Squamous Cell Carcinoma

Biomolecules, 2021
Selection of optimal control samples is crucial in expression profiling tumor samples. To address this issue, we performed microarray expression profiling of control samples routinely used in head and neck squamous cell carcinoma studies: human bronchial
Adam Ustaszewski, Magdalena Kostrzewska-Poczekaj, Joanna Janiszewska, Malgorzata Jarmuz-Szymczak, Malgorzata Wierzbicka, Joanna Marszal, Reidar Grénman, Maciej Giefing   +7 more
doaj   +1 more source

Lymphocytes in tumor-draining lymph nodes co-cultured with autologous tumor cells for adoptive cell therapy

Journal of Translational Medicine, 2022
Background Tumor-draining lymph nodes (TDLNs) are primary sites, where anti-tumor lymphocytes are primed to tumor-specific antigens and play pivotal roles in immune responses against tumors. Although adoptive cell therapy (ACT) using lymphocytes isolated
Kazumi Okamura, Satoshi Nagayama, Tomohiro Tate, Hiu Ting Chan, Kazuma Kiyotani, Yusuke Nakamura   +5 more
doaj   +1 more source

HDAC inhibition potentiates immunotherapy in triple negative breast cancer. [PDF]

, 2017
Triple-negative breast cancer (TNBC) represents a more aggressive and difficult subtype of breast cancer where responses to chemotherapy occur, but toxicity is significant and resistance often follows. Immunotherapy has shown promising results in various
Ali, Niwa, Budillon, Alfredo, Krings, Gregor, Munster, Pamela N, Park, Jeenah, Pawlowska, Nela, Rosenblum, Michael D, Terranova-Barberio, Manuela, Thomas, Scott   +8 more
core   +1 more source

CAFs affect the proliferation and treatment response of head and neck cancer spheroids during co-culturing in a unique in vitro model

Cancer Cell International, 2020
Background Head and neck squamous cell carcinoma (HNSCC) is a heterogeneous group of tumors for which the overall survival rate worldwide is around 60%. The tumor microenvironment, including cancer-associated fibroblasts (CAFs), is believed to affect the
Mustafa Magan, Emilia Wiechec, Karin Roberg   +2 more
doaj   +1 more source

Somatic gene therapy for cancer. The utility of transferrinfection in generating ‘tumor vaccines’ [PDF]

, 1993
The last few years have seen the development of a branch of somatic gene therapy which aims at strengthening the immune surveillance of the body, leading to eradication of disseminated cancer tumor cells and occult micrometastases after surgical removal ...
Aoki, Asher, Blankenstein, Bohle, Bubenik, Chen, Cloudman, Colombo, Cotten, Curiel, Dorsch, Dranoff, Ernst Wagner, Esumi, Fearon, Fearon, Gansbacher, Gansbacher, Georg Stingl, Golumbek, Groen, Hock, Hock, Itaya, Ito, Janeway, Kenne, Kurt Zatloukal, Kushtai, Lake, Lake, Lehner, Ley, Liebrich, Lindenmann, Linsley, Lurquin, Maraguchi, Matthew Cotten, Max L. Birnstiel, Nossal, Ohe, Ostrand-Rosenberg, Pardoll, Plaksin, Porgador, Restifo, Rollins, Roth, Russell, Schwartz, Tepper, Tepper, Townsend, Van der Bruggen, Van Pel, Wagner, Wallack, Walter Schmidt, Watanabe, Zatloukal   +60 more
core   +1 more source

Development of an acellular tumor extracellular matrix as a three-dimensional scaffold for tumor engineering. [PDF]

PLoS ONE, 2014
Tumor engineering is defined as the construction of three-dimensional (3D) tumors in vitro with tissue engineering approaches. The present 3D scaffolds for tumor engineering have several limitations in terms of structure and function.
Wei-Dong Lü, Lei Zhang, Chun-Lin Wu, Zhi-Gang Liu, Guang-Yan Lei, Jia Liu, Wei Gao, Ye-Rong Hu   +7 more
doaj   +1 more source

Specific antigen of tumor cell transformed by DNA extracted from SV-40 virus [PDF]

, 1967
In the immunofluorescent study it has been revealed that rabbit sera immunized with transformed cells induced by SV-40 DNA, produce circulating antibody capable of re:lcting with intranuclear antigens synthesized by SV-40 complyte virus transforming ...
Grace, James T., Hayashi, Kenj, Kimoto, Tetsuo, Okada, Shigeru, Shigehisa, Morio, Sogabe, Koichi   +5 more
core   +1 more source

Culture of Zollinger-Ellison Tumor Cells

Gastroenterology, 1975
We have successfully grown six Zollinger-Ellison tumors in vitro with use of a monlayer tissue culture technique. The initial gastrin concentration in the medium varied between 0 and 100 ng per ml. Many cytoplasmic secretory granules were seen in the cells of one culture population.
L M, Lichtenberger, J, Lechago, G J, Dockray, E, Passaro   +3 more
openaire   +2 more sources

DBCCR1 mediates death in cultured bladder tumor cells [PDF]

Oncogene, 2004
Chromosome 9, which is often partially or fully reduced to homozygosity in bladder cancer cells, harbors several tumor suppressor loci including deleted in bladder cancer chromosome region 1 (DBCCR1) at 9q32-33. To study DBCCR1 function, stable cell lines, inducible for DBCCR1 expression by tetracycline, were made, but the DBCCR1 protein was not ...
Kate O, Wright, Edward M, Messing, Jay E, Reeder   +2 more
openaire   +2 more sources

Docosahexaenoic acid (DHA) promotes immunogenic apoptosis in human multiple myeloma cells, induces autophagy and inhibits STAT3 in both tumor and dendritic cells [PDF]

, 2017
Docosahexaenoic acid (DHA), a ω-3 polyunsaturated fatty acid found in fish oil, is a multi-target agent and exerts anti-inflammatory and anticancer activities alone or in combination with chemotherapies.
D'Eliseo, Donatella, DI RENZO, Livia Maria, Santoni, Angela, Velotti, Francesca   +3 more
core   +1 more source