Results 241 to 250 of about 852,943 (301)

Activation of the integrated stress response and loss of cFLIP_L under glutamine limitation induce IL-8 gene expression and secretion in glutamine-dependent tumor cells. [PDF]

Cell Death Discov
Mora-Molina R, Fernández-Farrán FJ, López-Rivas A, Palacios C.   +3 more
europepmc   +1 more source

Double Cross‐Linked Hydrogel for Intra‐articular Injection as Modality for Macrophages Metabolic Reprogramming and Therapy of Rheumatoid Arthritis

Advanced Functional Materials, EarlyView.
A hydrogel for intra‐articular injection for the treatment of rheumatoid arthritis (RA) is formulated and comprehensively studied. After administration, the hydrogel induces a metabolic reprogramming of immunometabolism of macrophages to trigger fatty acid oxidation subsequently inducing polarization of anti‐inflammatory M2 macrophages. This results in
Yutong Song, Valentin A. Milichko, Ziqiao Ding, Wen Li, Bei Kang, Yunsheng Dou, Sona Krizkova, Zbynek Heger, Nan Li   +8 more
wiley   +1 more source

Chemoresistant tumor cell secretome potentiates immune suppression in triple negative breast cancer. [PDF]

Breast Cancer Res
Skourti E, Seip K, Mensali N, Jabeen S, Juell S, Øynebråten I, Pettersen S, Engebraaten O, Corthay A, Inderberg EM, Dolznig H, Mælandsmo GM, Egeland EV, Prasmickaite L.   +13 more
europepmc   +1 more source

Evolving Platinum‐Copper Nanostructures for Enhanced Photothermal Therapy and Controlled Copper Release in Cancer Therapy

Advanced Functional Materials, EarlyView.
Platinum‐Copper bimetallic nanoparticles may evolve depending on their synthesis under tumor microenvironment conditions and play a dual role as chemotherapeutic agents after releasing Cu ions and as near infrared photothermal agents with the Pt‐rich remaining frames.
Jose I. Garcia‐Peiro, María Sancho‐Albero, Silvia Miguel, Andrea Mosseri, Felipe Hornos, Rafael Contreras‐Montoya, Jose L. Hueso, Jesus Santamaria   +7 more
wiley   +1 more source

Autophagy inhibition potentiates anti-cancer activity of Sunitinib in kidney cancer cells. [PDF]

Biol Direct
Patergnani S, Zampieri P, Bianchi N, Ippolito C, Gafà R, Lanza G, Wieckowski MR, Pinton P, Aguiari G.   +8 more
europepmc   +1 more source

Ultrasoft Iontronics: Stretchable Diodes Enabled by Ionically Conductive Bottlebrush Elastomers

Advanced Functional Materials, EarlyView.
This work introduces a solvent‐free, ultrasoft, and stretchable ionic diode based on oppositely charged bottlebrush elastomers (BBEs). The BBE diode exhibits an ultralow Young's modulus (<23 kPa), a high rectification ratio of 46, and stretchability over 400%.
Xia Wu, Pengfei Xu, Zefang Zhang, Qi Yang, Xi Huang, Peng Pan, Xinyu Liu   +6 more
wiley   +1 more source

Therapeutic Efficacy of CD34-Derived Allogeneic Dendritic Cells Engineered to Express CD93, CD40L, and CXCL13 in Humanized Mouse Models of Pancreatic Cancer. [PDF]

Vaccines (Basel)
Huerta-Yepez S, Gonzalez JD, Sheik N, Beraki S, Kathirvel E, Rodriguez-Frandsen A, Chen PC, Sargsyan T, Mahammad S, Dybul MR, Chen L, Binette F, Jewett A.   +12 more
europepmc   +1 more source

Rosmarinic acid potentiates gefitinib in lung adenocarcinoma by modulating interactions between cancer cells and cancer-associated fibroblasts. [PDF]

Sci Rep
Li D, Lv Y, Hu L, Sun A, Sun L.
europepmc   +1 more source

Development of tetraculture spheroids as a versatile 3D model for personalized breast cancer research. [PDF]

Sci Rep
Piwocka O, Sterzyńska K, Malińska A, Suchorska WM, Kulcenty K.   +4 more
europepmc   +1 more source

ARNTL-mediated INO80-DHX15 axis reprograms the glycolytic metabolism and augments the progression of endometrial carcinoma. [PDF]

Cell Death Dis
Ye L, Jiang G, Sun Y, Li B.
europepmc   +1 more source