Results 241 to 250 of about 5,932,486 (309)

Protocol for short-term in vitro propagation of patient-derived group 4 medulloblastoma MBT375 tumor cells. [PDF]

STAR Protoc
Custers S, Venugopal C, Singh SK.
europepmc   +1 more source

A U‐shaped Microfluidic Platform for Culturing Vascularized Colorectal Cancer Spheroids Reveals Tumor–Endothelial Crosstalk and Invasion‐Associated Remodeling

Advanced Materials Technologies, EarlyView.
A closed U‐shaped microfluidic platform symmetrically embeds a single, size‐controlled HT29 colorectal cancer spheroid within a GFP‐HUVEC‐laden fibrin matrix. HT29 spheroids are associated with hyper‐branched endothelial network remodeling, while vascularized co‐culture is accompanied by anisotropic protrusive growth and EMT‐like marker changes in the ...
G. Cretti, M. Ballerini, A. Mantegazza, P. Occhetta, M. Rasponi   +4 more
wiley   +1 more source

CTHRC1⁺ cancer associated-fibroblasts promotes malignant progression of bladder cancer cells via inducing an immunosuppressive tumor microenvironment. [PDF]

Front Immunol
Wang M, Lin M, Wang Y.
europepmc   +1 more source

In‐House Manufacturing of 3D ECM Culture Chips via Vacuum Thermoforming for Enhanced Imaging Applications

Advanced Materials Technologies, EarlyView.
Desktop vacuum thermoforming enables rapid, low‐cost fabrication of 96‐channel polystyrene culture chips with very thin imaging interfaces. The resulting platform supports cell lines, primary cells, and patient‐derived organoids, and enables high‐resolution confocal microscopy and single‐cell visualization, providing an accessible approach for advanced
Aleksandra Fomina, Adam Tam, Jennifer Lam, Nila C. Wu, Nancy T. Li, Alison P. McGuigan   +5 more
wiley   +1 more source

The microenvironment dictates glyco-immune surveillance via HSF1-mediated metabolism. [PDF]

Sci Adv
Tharp KM, Park S, Timblin GA, Richards AL, Berg JA, Twells NM, Riley NM, Alvarez K, Lee A, Peltan EL, Shon DJ, Stevenson E, Tsui K, Palomba F, Lefebvre AEYT, Soens RW, Thangaraj JL, Ayad NME, Rhodenhiser JA, Ten Hoeve J, Healy K, Digman M, Dillin A, Krogan NJ, Bertozzi CR, Kaufman DS, Sinha S, Swaney DL, Mahal LK, Cantor JR, Paszek MJ, Weaver VM.   +31 more
europepmc   +1 more source

TGFβ Blockade by Inhibition of Enolase-1-Mediated Plasmin Targets Tumor-Associated Macrophages in Pancreatic Ductal Adenocarcinoma. [PDF]

Oncol Res
Chen ML, Chung IC, Huang KC, Chao KSC, Yuan TT.   +4 more
europepmc   +1 more source

Targeting FAM64A: a promising strategy to halt liver cancer angiogenesis and enhance immunity. [PDF]

Am J Cancer Res
Bai L, Yang X, Bai L, Ren Z, Gong H, Zhang Y, Chen H, Ma Z.   +7 more
europepmc   +1 more source

CHST1 Drives Immunotherapy Resistance in Triple-Negative Breast Cancer by Orchestrating an Immunosuppressive Microenvironment via the NKRF-CCL20-Macrophage Axis. [PDF]

Adv Sci (Weinh)
Jiang SH, Ying XH, Wang RQ, Zhang Q, Chen L, Shao ZM, Li JJ.   +6 more
europepmc   +1 more source

Spatiotemporally Ultrasound-Controlled Nanoparticles Reprogramming Immunostimulatory Antigen-Presenting Cancer-Associated Fibroblasts to Enhance Cancer Immunotherapy. [PDF]

Adv Sci (Weinh)
Ai C, Sun W, Zhao Y, Sun D, Meng T, Qi Y, Jiang F, Sun J, Gao Z, Yu D.   +9 more
europepmc   +1 more source

Vitamin C enhances cytotoxicity of CAR-and εTRuC-engineered γδ T cells and modulates Ca²⁺, NFAT, NF-κB and ERK signaling in human γδ T cells. [PDF]

Front Immunol
Zarobkiewicz M, Ma L, Juraske C, Cierna L, Kouakanou L, Krißmer SM, Fiala GJ, Peters C, Schamel WW, Kabelitz D.   +9 more
europepmc   +1 more source