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Immunofluorescent studies of cultured canine tumor cells
International Journal of Cancer, 1972AbstractThe indirect immunofluorescent (IF) test was used in an immunological survey of 17 sera from tumor‐bearing and normal dogs. These sera were reacted against 33 cultured canine tumor and normal cells. A high percentage (70%) of IF positive reactions were seen in cells derived from sarcomatous tumors while only 4% of the cultures from tumor types ...
Wilna A. Woods+5 more
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Antibody transport in cultured tumor cell layers
Journal of Controlled Release, 1998This review summarizes our recent in vitro studies of the factors affecting the tumor penetration of immunoconjugates. The studies were designed to probe the mechanisms of diffusion and convection, using a cultured layer of mouse melanoma cells as a model tumor cell layer and an antibody to the murine transferrin receptor as a model ligand.
P. A. Kitos+4 more
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Confrontation responses of normal and tumorous cells in culture
Experimental Cell Research, 1970Abstract 1. 1. A line of normal rat fibroblasts (NRF) was established and a diploid clone was obtained (NRF-C-1). NRF-C-1 cells grew in parallel array as monolayers in tissue culture and did not form tumors on inoculation into isologous newborn rats. 2. 2.
Catherine Armstrong Reznikoff+1 more
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GROWTH OF EHRLICH ASCITES TUMOR CELLS IN TISSUE CULTURE
Canadian Journal of Biochemistry and Physiology, 1960Null
Jackson, P W, Giuffre, N, Perlman, D
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Effect of a hypoxic tumor cell cytotoxic disulfide on the membrane and DNA of tumor cells in culture
Anti-Cancer Drugs, 1992A disulfide, n-butyl 2-imidazolyl disulfide (III-2), recently reported to be more toxic to EMT6 tumor cells under hypoxia has also been shown to be preferentially toxic to KHT/iv cells under hypoxia with an IC90 value 3-fold lower versus that measured in air. The IC90 values for both cell lines were markedly affected when the pHe was decreased.
Kirkpatrick Dl+5 more
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1995
Publisher Summary This chapter describes generally successful methods for culture initiation of tumor cells from multiple human and animal source tissues. The success rate of 80-90% for the initiation of viable primary cultures with the propensity to maintain the ability to divide and differentiate for at least two to three subcultures (which is 4-10
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Publisher Summary This chapter describes generally successful methods for culture initiation of tumor cells from multiple human and animal source tissues. The success rate of 80-90% for the initiation of viable primary cultures with the propensity to maintain the ability to divide and differentiate for at least two to three subcultures (which is 4-10
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Transformation of Cells in Human Bone Tumor Cultures
2015Two cell lines from tumors of 16 patients with osteosarcoma and two cell lines from 5 patients with giant cell tumor of bone showed conversion of cell type after 2 to 13 months in culture. Transformed cells of epithelial like morphology appeared in small focal areas and rapidly overgrew nontransformed cells.
Wilbur+4 more
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On the growth and stability of cell cultures and solid tumors
Journal of Theoretical Biology, 1976A theory is formulated to describe the growth and movement of certain cell cultures and solid tumors in response to an arbitrary distribution of nutrient. Conditions are established for the unstable development of a colony in which internal pressure forces overcome surface tension and adhesion.
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Study of the motility and contractility of cultured brain-tumor cells [PDF]
✓ The motility of cultured cells and contractility of their cytoplasmic microfilament system were studied in benign compared with malignant brain-tumor cells. Motility of cultured cells was continuously monitored in a perfusion chamber by a computerized microscope system equipped with an autotracking device.
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Influence of interferon on adriamycin uptake of cultured tumor cells
International Journal of Cancer, 1989AbstractEffect of human interferon β (IFNβ) or interferon γ (IFNγ) on cellular uptake of adriamycin (ADM) was measured in 3 in vitro‐cultured human tumor cell lines. Pre‐incubation of tumor cells with 100 lU/ml of IFNβ or γ for 6 hr resulted in an increased intracellular ADM concentration, but ADM efflux was not affected by the IFNs.
Tetsuya Yamamoto+2 more
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